Protein : Qrob_P0042900.2 Q. robur
Protein Identifier  ? Qrob_P0042900.2 Organism . Name  Quercus robur
Score  0.0 Score Type  egn
Protein Description  (M=7) PTHR10169:SF38 - DNA TOPOISOMERASE 2 (PTHR10169:SF38) Code Enzyme  EC:5.99.1.3
Gene Prediction Quality  validated Protein length 

Sequence

Length: 417  
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0 Synonyms

4 GO Terms

Identifier Name Description
GO:0003677 DNA binding Any molecular function by which a gene product interacts selectively and non-covalently with DNA (deoxyribonucleic acid).
GO:0005524 ATP binding Interacting selectively and non-covalently with ATP, adenosine 5'-triphosphate, a universally important coenzyme and enzyme regulator.
GO:0003918 DNA topoisomerase type II (ATP-hydrolyzing) activity Catalysis of a DNA topological transformation by transiently cleaving a pair of complementary DNA strands to form a gate through which a second double-stranded DNA segment is passed, after which the severed strands in the first DNA segment are rejoined; product release is coupled to ATP binding and hydrolysis; changes the linking number in multiples of 2.
GO:0006265 DNA topological change The process in which a transformation is induced in the topological structure of a double-stranded DNA helix, resulting in a change in linking number.

33 Blast

Analysis Hit Start End Strand Length Note Hit Coverage Hit Length Hit Pident E Val Hit Description
blastp_kegg lcl|rcu:RCOM_0966810 1 407 + 407 Gaps:48 36.72 1212 55.28 6e-122 DNA topoisomerase II putative (EC:1.3.1.74)
blastp_kegg lcl|tcc:TCM_042757 1 401 + 401 Gaps:50 29.94 1473 55.33 2e-110 DNA topoisomerase 2 isoform 1
blastp_kegg lcl|vvi:100253371 10 401 + 392 Gaps:56 29.55 1489 54.09 1e-104 DNA topoisomerase 2-like
blastp_kegg lcl|pop:POPTR_0009s06380g 8 408 + 401 Gaps:69 29.01 1482 53.95 1e-104 POPTRDRAFT_557797 DNA topoisomerase family protein
blastp_kegg lcl|mdm:103438420 8 415 + 408 Gaps:51 28.80 1462 55.34 8e-103 DNA topoisomerase 2-like
blastp_kegg lcl|pxb:103945915 10 415 + 406 Gaps:74 28.90 1467 54.25 1e-102 DNA topoisomerase 2-like
blastp_kegg lcl|pxb:103945911 10 415 + 406 Gaps:74 28.90 1467 54.25 1e-102 DNA topoisomerase 2-like
blastp_kegg lcl|pop:POPTR_0001s27120g 8 416 + 409 Gaps:57 28.96 1485 51.86 3e-100 POPTRDRAFT_706393 DNA topoisomerase family protein
blastp_kegg lcl|cit:102610705 10 401 + 392 Gaps:56 28.43 1456 52.66 2e-98 DNA topoisomerase 2-like
blastp_kegg lcl|cic:CICLE_v10030505mg 10 401 + 392 Gaps:55 28.38 1455 52.54 4e-98 hypothetical protein
blastp_pdb 3qx3_B 5 143 + 139 Gaps:4 17.06 803 35.04 4e-15 mol:protein length:803 DNA topoisomerase 2-beta
blastp_pdb 3qx3_A 5 143 + 139 Gaps:4 17.06 803 35.04 4e-15 mol:protein length:803 DNA topoisomerase 2-beta
blastp_pdb 2rgr_A 5 132 + 128 Gaps:20 18.71 759 30.99 2e-07 mol:protein length:759 DNA topoisomerase 2
blastp_pdb 1bjt_A 5 132 + 128 Gaps:20 17.91 793 30.99 2e-07 mol:protein length:793 TOPOISOMERASE II
blastp_pdb 1bgw_A 5 132 + 128 Gaps:20 17.91 793 30.99 2e-07 mol:protein length:793 TOPOISOMERASE
blastp_pdb 3l4k_A 5 132 + 128 Gaps:20 18.76 757 30.99 2e-07 mol:protein length:757 DNA topoisomerase 2
blastp_pdb 3l4j_A 5 132 + 128 Gaps:20 18.76 757 30.99 2e-07 mol:protein length:757 DNA topoisomerase 2
blastp_uniprot_sprot sp|O24308|TOP2_PEA 2 392 + 391 Gaps:63 30.10 1462 39.77 8e-59 DNA topoisomerase 2 OS Pisum sativum GN TOP2 PE 2 SV 1
blastp_uniprot_sprot sp|P30182|TOP2_ARATH 3 196 + 194 Gaps:23 14.73 1473 44.24 1e-38 DNA topoisomerase 2 OS Arabidopsis thaliana GN TOP2 PE 2 SV 2
blastp_uniprot_sprot sp|P08096|TOP2_SCHPO 5 138 + 134 Gaps:10 8.75 1485 39.23 2e-17 DNA topoisomerase 2 OS Schizosaccharomyces pombe (strain 972 / ATCC 24843) GN top2 PE 1 SV 2
blastp_uniprot_sprot sp|Q02880|TOP2B_HUMAN 5 193 + 189 Gaps:4 11.50 1626 32.09 5e-15 DNA topoisomerase 2-beta OS Homo sapiens GN TOP2B PE 1 SV 3
blastp_uniprot_sprot sp|Q64399|TOP2B_CRILO 5 195 + 191 Gaps:4 11.72 1612 31.22 5e-15 DNA topoisomerase 2-beta OS Cricetulus longicaudatus GN TOP2B PE 2 SV 1
blastp_uniprot_sprot sp|Q64511|TOP2B_MOUSE 5 195 + 191 Gaps:4 11.72 1612 30.69 1e-14 DNA topoisomerase 2-beta OS Mus musculus GN Top2b PE 1 SV 2
blastp_uniprot_sprot sp|Q55BP5|TOP2_DICDI 5 136 + 132 Gaps:8 9.20 1521 35.71 2e-12 Probable DNA topoisomerase 2 OS Dictyostelium discoideum GN top2 PE 3 SV 1
blastp_uniprot_sprot sp|Q01879|TOP2_PICGU 3 205 + 203 Gaps:21 15.29 1400 29.91 1e-11 DNA topoisomerase 2 OS Meyerozyma guilliermondii (strain ATCC 6260 / CBS 566 / DSM 6381 / JCM 1539 / NBRC 10279 / NRRL Y-324) GN TOP2 PE 3 SV 3
blastp_uniprot_sprot sp|Q9Y8G8|TOP2_PENCH 3 129 + 127 Gaps:5 7.69 1587 36.89 2e-11 DNA topoisomerase 2 OS Penicillium chrysogenum GN TOP2 PE 3 SV 1
blastp_uniprot_sprot sp|P41001|TOP2_PLAFK 6 139 + 134 Gaps:11 9.51 1398 34.59 9e-11 DNA topoisomerase 2 OS Plasmodium falciparum (isolate K1 / Thailand) GN TOP2 PE 3 SV 1
rpsblast_cdd gnl|CDD|178775 3 411 + 409 Gaps:43 29.49 1465 55.79 1e-102 PLN03237 PLN03237 DNA topoisomerase 2 Provisional.
rpsblast_cdd gnl|CDD|178674 3 136 + 134 Gaps:5 11.37 1135 54.26 2e-34 PLN03128 PLN03128 DNA topoisomerase 2 Provisional.
rpsblast_cdd gnl|CDD|185451 1 416 + 416 Gaps:49 27.16 1388 25.73 4e-32 PTZ00108 PTZ00108 DNA topoisomerase 2-like protein Provisional.

6 Domain Motifs

Analysis Begin End Length Domain Identifier Cross Ref Description Inter Pro
PANTHER 3 288 286 PTHR10169 none none none
Pfam 4 129 126 PF00521 none DNA gyrase/topoisomerase IV, subunit A IPR002205
Coils 98 119 22 Coil none none none
SUPERFAMILY 4 139 136 SSF56719 none none IPR013760
Gene3D 4 141 138 G3DSA:1.10.268.10 none none IPR013757
PANTHER 3 288 286 PTHR10169:SF38 none none none

0 Localization

5 Qtllist

Qtl Name Chromosome Name Linkage Group Prox Marker Dist Marker Position QTL Pos One Pos Two Test Type Test Value R 2
Bourran2_2014_vSeqBC_3P Qrob_Chr10 10 s_1A6CK6_610 v_7092_29 4,28 0 23,27 lod 2,8619 7
Bourran2_2015_nEpis_3P Qrob_Chr12 12 s_1AOES6_1466 s_1B0DDG_1094 28,97 28,55 30,1 lod 3.6 8.4
Bourran2_2014_nFork*_3P Qrob_Chr06 6 v_12930_125 s_1AMZEI_909 34,28 7,43 41,48 lod 2,4044 5,5
Bourran2_2015_nSeqBC_3P Qrob_Chr11 11 s_1DG9PM_867 s_1BZ083_1312 26,06 25,47 27,72 lod 3.6 7.1
Bourran2_2015_nP_3P Qrob_Chr12 12 v_10140_295 v_838_303 16 14,69 18,01 lod 5.1 13.7

0 Targeting