Protein : Qrob_P0035440.2 Q. robur
Protein Identifier  ? Qrob_P0035440.2 Organism . Name  Quercus robur
Score  100.0 Score Type  egn
Protein Description  (M=1) K09651 - rhomboid domain-containing protein 1 [EC:3.4.21.-] Code Enzyme  EC:3.4.21.105
Gene Prediction Quality  validated Protein length 

Sequence

Length: 331  
Kegg Orthology  K09651
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0 Synonyms

3 GO Terms

Identifier Name Description
GO:0008270 zinc ion binding Interacting selectively and non-covalently with zinc (Zn) ions.
GO:0016021 integral component of membrane The component of a membrane consisting of the gene products and protein complexes having at least some part of their peptide sequence embedded in the hydrophobic region of the membrane.
GO:0004252 serine-type endopeptidase activity Catalysis of the hydrolysis of internal, alpha-peptide bonds in a polypeptide chain by a catalytic mechanism that involves a catalytic triad consisting of a serine nucleophile that is activated by a proton relay involving an acidic residue (e.g. aspartate or glutamate) and a basic residue (usually histidine).

20 Blast

Analysis Hit Start End Strand Length Note Hit Coverage Hit Length Hit Pident E Val Hit Description
blastp_kegg lcl|cit:102612667 1 329 + 329 Gaps:14 100.00 329 74.16 3e-165 uncharacterized LOC102612667
blastp_kegg lcl|cic:CICLE_v10021112mg 1 329 + 329 Gaps:13 100.00 328 73.48 1e-163 hypothetical protein
blastp_kegg lcl|fve:101292109 1 330 + 330 Gaps:8 100.00 332 68.07 4e-156 uncharacterized protein At3g17611-like
blastp_kegg lcl|pop:POPTR_0010s00720g 8 329 + 322 Gaps:4 96.95 328 72.01 1e-155 POPTRDRAFT_657794 rhomboid family protein
blastp_kegg lcl|vvi:100244285 1 330 + 330 Gaps:10 100.00 328 74.39 1e-154 uncharacterized LOC100244285
blastp_kegg lcl|tcc:TCM_036040 4 329 + 326 Gaps:10 98.19 332 69.63 7e-153 RHOMBOID-like protein 14 isoform 1
blastp_kegg lcl|rcu:RCOM_1004220 1 295 + 295 Gaps:6 91.38 325 76.77 9e-152 hypothetical protein
blastp_kegg lcl|gmx:100794217 8 329 + 322 Gaps:17 92.47 332 69.06 5e-149 uncharacterized LOC100794217
blastp_kegg lcl|atr:s00045p00154580 8 330 + 323 Gaps:1 96.70 333 63.98 1e-147 AMTR_s00045p00154580 hypothetical protein
blastp_kegg lcl|pmum:103322200 8 314 + 307 Gaps:5 91.62 334 67.32 1e-147 uncharacterized protein At3g17611
blastp_uniprot_sprot sp|Q8RXW0|Y3761_ARATH 3 328 + 326 Gaps:5 97.31 334 65.54 5e-139 Uncharacterized protein At3g17611 OS Arabidopsis thaliana GN At3g17611 PE 2 SV 1
blastp_uniprot_sprot sp|Q8TEB9|RHBL4_HUMAN 27 235 + 209 Gaps:18 61.90 315 41.03 1e-34 Rhomboid-related protein 4 OS Homo sapiens GN RHBDD1 PE 1 SV 1
blastp_uniprot_sprot sp|Q4V8F3|RHBL4_RAT 3 328 + 326 Gaps:52 98.10 316 35.16 2e-33 Rhomboid-related protein 4 OS Rattus norvegicus GN Rhbdd1 PE 2 SV 1
blastp_uniprot_sprot sp|Q8BHC7|RHBL4_MOUSE 3 212 + 210 Gaps:18 64.76 315 40.20 8e-33 Rhomboid-related protein 4 OS Mus musculus GN Rhbdd1 PE 1 SV 1
blastp_uniprot_sprot sp|Q5RBS4|RHBL4_PONAB 3 232 + 230 Gaps:18 67.92 318 37.96 4e-32 Rhomboid-related protein 4 OS Pongo abelii GN RHBDD1 PE 2 SV 1
blastp_uniprot_sprot sp|Q8LB17|Y3846_ARATH 56 316 + 261 Gaps:25 64.02 403 32.17 4e-17 Uncharacterized protein At3g58460 OS Arabidopsis thaliana GN At3g58460 PE 1 SV 2
blastp_uniprot_sprot sp|Q5UQ86|RHBDL_MIMIV 67 213 + 147 Gaps:18 76.61 171 37.40 6e-06 Putative rhomboid protein L523 OS Acanthamoeba polyphaga mimivirus GN MIMI_L523 PE 3 SV 1
rpsblast_cdd gnl|CDD|201925 64 218 + 155 Gaps:20 99.32 146 28.97 8e-14 pfam01694 Rhomboid Rhomboid family. This family contains integral membrane proteins that are related to Drosophila rhomboid protein. Members of this family are found in bacteria and eukaryotes. Rhomboid promotes the cleavage of the membrane-anchored TGF-alpha-like growth factor Spitz allowing it to activate the Drosophila EGF receptor. Analysis has shown that Rhomboid-1 is an intramembrane serine protease (EC:3.4.21.105). Parasite-encoded rhomboid enzymes are also important for invasion of host cells by Toxoplasma and the malaria parasite.
rpsblast_cdd gnl|CDD|31049 18 213 + 196 Gaps:27 88.16 228 27.86 1e-08 COG0705 GlpG Uncharacterized membrane protein (homolog of Drosophila rhomboid) [General function prediction only].
rpsblast_kog gnl|CDD|37843 27 283 + 257 Gaps:12 96.51 258 34.14 7e-45 KOG2632 KOG2632 KOG2632 Rhomboid family proteins [Function unknown].

16 Domain Motifs

Analysis Begin End Length Domain Identifier Cross Ref Description Inter Pro
SUPERFAMILY 25 212 188 SSF144091 none none none
Phobius 129 139 11 CYTOPLASMIC_DOMAIN none Region of a membrane-bound protein predicted to be outside the membrane, in the cytoplasm. none
Phobius 96 106 11 NON_CYTOPLASMIC_DOMAIN none Region of a membrane-bound protein predicted to be outside the membrane, in the extracellular region. none
Phobius 1 72 72 CYTOPLASMIC_DOMAIN none Region of a membrane-bound protein predicted to be outside the membrane, in the cytoplasm. none
Gene3D 25 211 187 G3DSA:1.20.1540.10 none none IPR022764
Phobius 161 179 19 NON_CYTOPLASMIC_DOMAIN none Region of a membrane-bound protein predicted to be outside the membrane, in the extracellular region. none
ProSitePatterns 273 292 20 PS01358 none Zinc finger RanBP2-type signature. IPR001876
PANTHER 2 325 324 PTHR22790:SF7 none none none
Phobius 107 128 22 TRANSMEMBRANE none Region of a membrane-bound protein predicted to be embedded in the membrane. none
Phobius 140 160 21 TRANSMEMBRANE none Region of a membrane-bound protein predicted to be embedded in the membrane. none
Phobius 180 211 32 TRANSMEMBRANE none Region of a membrane-bound protein predicted to be embedded in the membrane. none
SUPERFAMILY 269 296 28 SSF90209 none none none
Phobius 212 330 119 CYTOPLASMIC_DOMAIN none Region of a membrane-bound protein predicted to be outside the membrane, in the cytoplasm. none
PANTHER 2 325 324 PTHR22790 none none none
Pfam 67 212 146 PF01694 none Rhomboid family IPR022764
Phobius 73 95 23 TRANSMEMBRANE none Region of a membrane-bound protein predicted to be embedded in the membrane. none

4 Localization

Analysis Start End Length
TMHMM 73 95 22
TMHMM 145 167 22
TMHMM 110 132 22
TMHMM 187 209 22

18 Qtllist

Qtl Name Chromosome Name Linkage Group Prox Marker Dist Marker Position QTL Pos One Pos Two Test Type Test Value R 2
Champenoux_2015_nPriLBD_3P Qrob_Chr10 10 v_15000_157 v_15000_310 15,68 15,9 15,91 lod 2.4 5.5
Bourran2_2014_nSecLBD_3P Qrob_Chr08 8 s_1BN2OD_551 s_1B5AYF_599 17,17 0 43,51 lod 1,9229 4,4
Bourran2_2014_nLBD*_3P Qrob_Chr08 8 v_5216_549 v_11837_70 12,25 0 35,55 lod 2,5951 6
Bourran2_2014_nP*_3P Qrob_Chr08 8 v_5216_549 v_11837_70 12,19 0 31,97 lod 2,8472 6
Bourran2_2002_QTL11_peak_Bud_burst_A4 Qrob_Chr06 6 s_1C41PA_791 s_1AM1AV_1141 19,17 0 34,57 lod 2,3 2,9
Bourran2_2014_aSeqBC_3P Qrob_Chr06 6 v_506_189 v_686_77 30,72 13,58 43,48 lod 2,2746 6,3
Bourran2_2014_aSeqBC*_A4 Qrob_Chr06 6 s_2F5MK3_712 v_444_355 27,13 14,86 39,46 lod 3,7847 9,8
Bourran2_2014_nEpis*_3P Qrob_Chr08 8 s_1DA4QW_688 s_1DNI7D_820 17,96 0 37,75 lod 2,9745 7,5
Bourran2_2014_nEpis*_A4 Qrob_Chr07 7 v_12400_446 s_1BPEBU_1211 6,93 0 15,13 lod 4,7411 11
Bourran2_2014_nFork*_3P Qrob_Chr06 6 v_12930_125 s_1AMZEI_909 34,28 7,43 41,48 lod 2,4044 5,5
Bourran2_2014_nLBD_A4 Qrob_Chr06 6 v_12930_125 s_1AMZEI_909 37,41 9,8 50,1 lod 1,9524 4,1
Bourran2_2014_nPriBD_A4 Qrob_Chr06 6 v_12930_125 s_1AMZEI_909 34,51 3,36 51,86 lod 1,6747 3,9
Bourran2_2014_nPriLBD*_3P Qrob_Chr11 11 v_12066_307 s_1B15GJ_447 3,37 0,57 16,17 lod 3,4299 6,9
Bourran2_2014_nSecLBD_A4 Qrob_Chr07 7 v_8327_222 s_1A4WGY_363 16,04 0 44,69 lod 2,6373 6,5
Bourran2_2014_vEpiBC_A4 Qrob_Chr06 6 v_12930_125 s_1AMZEI_909 37,55 14,41 50,01 lod 1,7882 4,8
Champenoux_2015_nEpis_3P Qrob_Chr11 11 s_1DG9PM_867 s_1BZ083_1312 26,53 25,47 27,72 lod 4.4 8.9
Champenoux_2015_nP_3P Qrob_Chr06 6 s_1A386O_228 s_1AYZFS_603 27,03 26,47 27,34 lod 2.8 7.2
Bourran2_2014_nPriBD*_3P Qrob_Chr06 6 s_1B6WLL_980 v_10064_133 11,49 0 31,52 lod 4,1208 9,1

1 Targeting

Analysis Start End Length Location Reliability Signal Peptide Cut Off Mitochondrion Cut Off Network Signal Peptide Length
TargetP 1 81   Mitochondrion 4 0.351 0.714 NON-PLANT 81