GO:0005515
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protein binding
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Interacting selectively and non-covalently with any protein or protein complex (a complex of two or more proteins that may include other nonprotein molecules). |
GO:0003677
|
DNA binding
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Any molecular function by which a gene product interacts selectively and non-covalently with DNA (deoxyribonucleic acid). |
GO:0005524
|
ATP binding
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Interacting selectively and non-covalently with ATP, adenosine 5'-triphosphate, a universally important coenzyme and enzyme regulator. |
GO:0009058
|
biosynthetic process
|
The chemical reactions and pathways resulting in the formation of substances; typically the energy-requiring part of metabolism in which simpler substances are transformed into more complex ones. |
GO:0005783
|
endoplasmic reticulum
|
The irregular network of unit membranes, visible only by electron microscopy, that occurs in the cytoplasm of many eukaryotic cells. The membranes form a complex meshwork of tubular channels, which are often expanded into slitlike cavities called cisternae. The ER takes two forms, rough (or granular), with ribosomes adhering to the outer surface, and smooth (with no ribosomes attached). |
GO:0006457
|
protein folding
|
The process of assisting in the covalent and noncovalent assembly of single chain polypeptides or multisubunit complexes into the correct tertiary structure. |
GO:0051082
|
unfolded protein binding
|
Interacting selectively and non-covalently with an unfolded protein. |
GO:0005509
|
calcium ion binding
|
Interacting selectively and non-covalently with calcium ions (Ca2+). |
GO:0003918
|
DNA topoisomerase type II (ATP-hydrolyzing) activity
|
Catalysis of a DNA topological transformation by transiently cleaving a pair of complementary DNA strands to form a gate through which a second double-stranded DNA segment is passed, after which the severed strands in the first DNA segment are rejoined; product release is coupled to ATP binding and hydrolysis; changes the linking number in multiples of 2. |
GO:0006265
|
DNA topological change
|
The process in which a transformation is induced in the topological structure of a double-stranded DNA helix, resulting in a change in linking number. |
GO:0016851
|
magnesium chelatase activity
|
Catalysis of the reaction: ATP + H(2)O + Mg(2+) + protoporphyrin IX = ADP + 2 H(+) + magnesium protoporphyrin IX + phosphate. |