Protein : Qrob_P0033410.2 Q. robur
Protein Identifier  ? Qrob_P0033410.2 Organism . Name  Quercus robur
Score  100.0 Score Type  egn
Protein Description  (M=3) 1.5.1.5 - Methylenetetrahydrofolate dehydrogenase (NADP(+)). Code Enzyme  EC:3.5.4.9, EC:1.5.1.5
Gene Prediction Quality  validated Protein length 

Sequence

Length: 370  
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0 Synonyms

4 GO Terms

Identifier Name Description
GO:0055114 oxidation-reduction process A metabolic process that results in the removal or addition of one or more electrons to or from a substance, with or without the concomitant removal or addition of a proton or protons.
GO:0003824 catalytic activity Catalysis of a biochemical reaction at physiological temperatures. In biologically catalyzed reactions, the reactants are known as substrates, and the catalysts are naturally occurring macromolecular substances known as enzymes. Enzymes possess specific binding sites for substrates, and are usually composed wholly or largely of protein, but RNA that has catalytic activity (ribozyme) is often also regarded as enzymatic.
GO:0004488 methylenetetrahydrofolate dehydrogenase (NADP+) activity Catalysis of the reaction: 5,10-methylenetetrahydrofolate + NADP(+) = 5,10-methenyltetrahydrofolate + NADPH.
GO:0009396 folic acid-containing compound biosynthetic process The chemical reactions and pathways resulting in the formation of folic acid and its derivatives.

42 Blast

Analysis Hit Start End Strand Length Note Hit Coverage Hit Length Hit Pident E Val Hit Description
blastp_kegg lcl|pper:PRUPE_ppa007647mg 14 369 + 356 Gaps:10 97.22 360 84.00 0.0 hypothetical protein
blastp_kegg lcl|pmum:103331884 14 369 + 356 Gaps:10 97.22 360 84.29 0.0 bifunctional protein FolD 4 chloroplastic
blastp_kegg lcl|cic:CICLE_v10020642mg 14 369 + 356 Gaps:10 96.50 371 81.56 0.0 hypothetical protein
blastp_kegg lcl|pop:POPTR_0002s15850g 14 369 + 356 Gaps:1 97.28 367 78.71 0.0 POPTRDRAFT_552147 hypothetical protein
blastp_kegg lcl|cit:102612232 14 369 + 356 Gaps:14 96.53 375 80.94 0.0 bifunctional protein FolD 4 chloroplastic-like
blastp_kegg lcl|tcc:TCM_005379 12 369 + 358 Gaps:10 97.79 362 80.51 0.0 Amino acid dehydrogenase family protein
blastp_kegg lcl|rcu:RCOM_0333230 14 369 + 356 none 97.27 366 78.65 0.0 methylenetetrahydrofolate dehydrogenase putative (EC:3.5.4.9)
blastp_kegg lcl|csv:101230915 15 369 + 355 Gaps:4 96.69 363 78.92 0.0 bifunctional protein FolD-like
blastp_kegg lcl|csv:101213328 15 369 + 355 Gaps:4 96.69 363 78.92 0.0 bifunctional protein FolD-like
blastp_kegg lcl|cmo:103483291 15 369 + 355 Gaps:4 96.69 363 78.06 0.0 bifunctional protein FolD 4 chloroplastic
blastp_pdb 4a26_B 77 363 + 287 Gaps:5 96.67 300 55.17 3e-103 mol:protein length:300 PUTATIVE C-1-TETRAHYDROFOLATE SYNTHASE CYTOP
blastp_pdb 4a26_A 77 363 + 287 Gaps:5 96.67 300 55.17 3e-103 mol:protein length:300 PUTATIVE C-1-TETRAHYDROFOLATE SYNTHASE CYTOP
blastp_pdb 1a4i_B 78 365 + 288 Gaps:3 96.68 301 50.52 7e-98 mol:protein length:301 METHYLENETETRAHYDROFOLATE DEHYDROGENASE / MET
blastp_pdb 1a4i_A 78 365 + 288 Gaps:3 96.68 301 50.52 7e-98 mol:protein length:301 METHYLENETETRAHYDROFOLATE DEHYDROGENASE / MET
blastp_pdb 1dig_B 78 365 + 288 Gaps:3 95.10 306 50.52 8e-98 mol:protein length:306 METHYLENETETRAHYDROFOLATE DEHYDROGENASE / CYC
blastp_pdb 1dig_A 78 365 + 288 Gaps:3 95.10 306 50.52 8e-98 mol:protein length:306 METHYLENETETRAHYDROFOLATE DEHYDROGENASE / CYC
blastp_pdb 1dib_B 78 365 + 288 Gaps:3 95.10 306 50.52 8e-98 mol:protein length:306 METHYLENETETRAHYDROFOLATE DEHYDROGENASE/CYCLO
blastp_pdb 1dib_A 78 365 + 288 Gaps:3 95.10 306 50.52 8e-98 mol:protein length:306 METHYLENETETRAHYDROFOLATE DEHYDROGENASE/CYCLO
blastp_pdb 1dia_B 78 365 + 288 Gaps:3 95.10 306 50.52 8e-98 mol:protein length:306 METHYLENETETRAHYDROFOLATE DEHYDROGENASE/CYCLO
blastp_pdb 1dia_A 78 365 + 288 Gaps:3 95.10 306 50.52 8e-98 mol:protein length:306 METHYLENETETRAHYDROFOLATE DEHYDROGENASE/CYCLO
blastp_uniprot_sprot sp|O65271|FOLD4_ARATH 14 369 + 356 Gaps:6 97.22 360 78.29 0.0 Bifunctional protein FolD 4 chloroplastic OS Arabidopsis thaliana GN FOLD4 PE 1 SV 1
blastp_uniprot_sprot sp|O65269|FOLD3_ARATH 14 369 + 356 Gaps:60 98.06 310 74.01 4e-146 Bifunctional protein FolD 3 chloroplastic OS Arabidopsis thaliana GN FOLD3 PE 3 SV 1
blastp_uniprot_sprot sp|A2RVV7|FOLD1_ARATH 62 365 + 304 none 86.36 352 65.79 4e-143 Bifunctional protein FolD 1 mitochondrial OS Arabidopsis thaliana GN FOLD1 PE 1 SV 1
blastp_uniprot_sprot sp|Q9LHH7|FOLD2_ARATH 73 365 + 293 none 97.99 299 63.82 5e-137 Bifunctional protein FolD 2 OS Arabidopsis thaliana GN FOLD2 PE 1 SV 1
blastp_uniprot_sprot sp|B9M769|FOLD_GEODF 78 364 + 287 Gaps:9 99.29 280 57.91 5e-105 Bifunctional protein FolD OS Geobacter daltonii (strain DSM 22248 / JCM 15807 / FRC-32) GN folD PE 3 SV 1
blastp_uniprot_sprot sp|A0LE04|FOLD_MAGSM 78 368 + 291 Gaps:8 99.30 285 57.95 2e-104 Bifunctional protein FolD OS Magnetococcus sp. (strain MC-1) GN folD PE 3 SV 1
blastp_uniprot_sprot sp|A5GAM5|FOLD_GEOUR 78 364 + 287 Gaps:9 99.29 280 56.12 5e-102 Bifunctional protein FolD OS Geobacter uraniireducens (strain Rf4) GN folD PE 3 SV 1
blastp_uniprot_sprot sp|Q2RIB4|FOLD_MOOTA 78 364 + 287 Gaps:9 99.29 280 56.47 7e-102 Bifunctional protein FolD OS Moorella thermoacetica (strain ATCC 39073) GN folD PE 3 SV 1
blastp_uniprot_sprot sp|Q73RS2|FOLD_TREDE 77 369 + 293 Gaps:5 99.66 293 52.40 2e-100 Bifunctional protein FolD OS Treponema denticola (strain ATCC 35405 / CIP 103919 / DSM 14222) GN folD PE 3 SV 1
blastp_uniprot_sprot sp|Q3ASI0|FOLD_CHLCH 80 368 + 289 Gaps:4 99.32 295 51.88 1e-99 Bifunctional protein FolD OS Chlorobium chlorochromatii (strain CaD3) GN folD PE 3 SV 1

15 Domain Motifs

Analysis Begin End Length Domain Identifier Cross Ref Description Inter Pro
Gene3D 217 347 131 G3DSA:3.40.50.720 none none IPR016040
PRINTS 322 338 17 PR00085 "KEGG:00670+1.5.1.5+3.5.4.9","KEGG:00720+1.5.1.5+3.5.4.9","MetaCyc:PWY-1722","MetaCyc:PWY-2201","MetaCyc:PWY-3841","MetaCyc:PWY-5030","MetaCyc:PWY-5497","MetaCyc:PWY-6613","UniPathway:UPA00193" Tetrahydrofolate dehydrogenase/cyclohydrolase family signature IPR000672
PRINTS 150 177 28 PR00085 "KEGG:00670+1.5.1.5+3.5.4.9","KEGG:00720+1.5.1.5+3.5.4.9","MetaCyc:PWY-1722","MetaCyc:PWY-2201","MetaCyc:PWY-3841","MetaCyc:PWY-5030","MetaCyc:PWY-5497","MetaCyc:PWY-6613","UniPathway:UPA00193" Tetrahydrofolate dehydrogenase/cyclohydrolase family signature IPR000672
PRINTS 232 252 21 PR00085 "KEGG:00670+1.5.1.5+3.5.4.9","KEGG:00720+1.5.1.5+3.5.4.9","MetaCyc:PWY-1722","MetaCyc:PWY-2201","MetaCyc:PWY-3841","MetaCyc:PWY-5030","MetaCyc:PWY-5497","MetaCyc:PWY-6613","UniPathway:UPA00193" Tetrahydrofolate dehydrogenase/cyclohydrolase family signature IPR000672
PRINTS 185 206 22 PR00085 "KEGG:00670+1.5.1.5+3.5.4.9","KEGG:00720+1.5.1.5+3.5.4.9","MetaCyc:PWY-1722","MetaCyc:PWY-2201","MetaCyc:PWY-3841","MetaCyc:PWY-5030","MetaCyc:PWY-5497","MetaCyc:PWY-6613","UniPathway:UPA00193" Tetrahydrofolate dehydrogenase/cyclohydrolase family signature IPR000672
PRINTS 109 131 23 PR00085 "KEGG:00670+1.5.1.5+3.5.4.9","KEGG:00720+1.5.1.5+3.5.4.9","MetaCyc:PWY-1722","MetaCyc:PWY-2201","MetaCyc:PWY-3841","MetaCyc:PWY-5030","MetaCyc:PWY-5497","MetaCyc:PWY-6613","UniPathway:UPA00193" Tetrahydrofolate dehydrogenase/cyclohydrolase family signature IPR000672
PRINTS 339 357 19 PR00085 "KEGG:00670+1.5.1.5+3.5.4.9","KEGG:00720+1.5.1.5+3.5.4.9","MetaCyc:PWY-1722","MetaCyc:PWY-2201","MetaCyc:PWY-3841","MetaCyc:PWY-5030","MetaCyc:PWY-5497","MetaCyc:PWY-6613","UniPathway:UPA00193" Tetrahydrofolate dehydrogenase/cyclohydrolase family signature IPR000672
PRINTS 281 310 30 PR00085 "KEGG:00670+1.5.1.5+3.5.4.9","KEGG:00720+1.5.1.5+3.5.4.9","MetaCyc:PWY-1722","MetaCyc:PWY-2201","MetaCyc:PWY-3841","MetaCyc:PWY-5030","MetaCyc:PWY-5497","MetaCyc:PWY-6613","UniPathway:UPA00193" Tetrahydrofolate dehydrogenase/cyclohydrolase family signature IPR000672
SUPERFAMILY 198 363 166 SSF51735 none none none
ProSitePatterns 343 351 9 PS00767 "KEGG:00670+1.5.1.5+3.5.4.9","KEGG:00720+1.5.1.5+3.5.4.9","MetaCyc:PWY-1722","MetaCyc:PWY-2201","MetaCyc:PWY-3841","MetaCyc:PWY-5030","MetaCyc:PWY-5497","MetaCyc:PWY-6613","UniPathway:UPA00193" Tetrahydrofolate dehydrogenase/cyclohydrolase signature 2. IPR020867
Pfam 79 196 118 PF00763 "KEGG:00670+1.5.1.5+3.5.4.9","KEGG:00720+1.5.1.5+3.5.4.9","MetaCyc:PWY-1722","MetaCyc:PWY-2201","MetaCyc:PWY-3841","MetaCyc:PWY-5030","MetaCyc:PWY-5497","MetaCyc:PWY-6613","UniPathway:UPA00193" Tetrahydrofolate dehydrogenase/cyclohydrolase, catalytic domain IPR020630
SUPERFAMILY 78 197 120 SSF53223 none none none
PANTHER 50 369 320 PTHR10025 none none none
Pfam 199 364 166 PF02882 "KEGG:00670+1.5.1.5+3.5.4.9","KEGG:00720+1.5.1.5+3.5.4.9","MetaCyc:PWY-1722","MetaCyc:PWY-2201","MetaCyc:PWY-3841","MetaCyc:PWY-5030","MetaCyc:PWY-5497","MetaCyc:PWY-6613","UniPathway:UPA00193" Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain IPR020631
Gene3D 82 216 135 G3DSA:3.40.192.10 none none none

0 Localization

11 Qtllist

Qtl Name Chromosome Name Linkage Group Prox Marker Dist Marker Position QTL Pos One Pos Two Test Type Test Value R 2
Bourran2_2014_nSecLBD_3P Qrob_Chr08 8 s_1BN2OD_551 s_1B5AYF_599 17,17 0 43,51 lod 1,9229 4,4
Bourran2_2015_nEpiBC_3P Qrob_Chr12 12 s_1B73S5_217 v_7050_211 28,31 26,37 28,45 lod 4.5 11.6
Bourran2_2014_aSeqBC_A4 Qrob_Chr08 8 v_15999_278 v_AP13YL15_395 32,52 4,22 57,22 lod 2,7561 6,7
Bourran2_2014_nFork*_A4 Qrob_Chr08 8 PIE175 s_1CD7GJ_1398 31,22 5,24 57,24 lod 2,6724 6,8
Bourran2_2014_nLBD*_3P Qrob_Chr08 8 v_5216_549 v_11837_70 12,25 0 35,55 lod 2,5951 6
Bourran2_2014_nP*_3P Qrob_Chr08 8 v_5216_549 v_11837_70 12,19 0 31,97 lod 2,8472 6
Bourran2_2014_nPriLBD_3P Qrob_Chr08 8 v_5216_549 v_11837_70 12,36 0 30,43 lod 2,5806 5,1
Bourran2_2015_rEpiBC_3P Qrob_Chr08 8 s_A9TNV_543 v_11837_70 9,93 9,83 11,15 lod 3.3 7.3
Champenoux_2015_nSeqBC_A4 Qrob_Chr08 8 v_AD7YD13_501 s_1A7IED_780 43,44 43,42 43,99 lod 3.7 8.9
Bourran2_2014_nEpis*_3P Qrob_Chr08 8 s_1DA4QW_688 s_1DNI7D_820 17,96 0 37,75 lod 2,9745 7,5
Bourran2_2014_nPriBD_3P Qrob_Chr11 11 v_11486_194 s_1AT3E_2335 5,54 0,4 20,6 lod 2,6345 5,9

1 Targeting

Analysis Start End Length Location Reliability Signal Peptide Cut Off Mitochondrion Cut Off Network Signal Peptide Length
TargetP 1 49   Mitochondrion 5 0.041 0.569 NON-PLANT 49