GRS - Genome Report System

Leptosphaeria maculans GRS

Functional annotation

Lema_P123560.1

Gene Identifier

DbXrefs

Domain/Motif (Interproscan results)

Localization / Targeting

Predicted function

Blast based analysis

Analysis	Hit	start	end	length	Note	Hit coverage	Hit length	Hit pident	Hit pcons	eValue	Hit description
blastp_kegg	xtr:100170433	1	181	181	n/a	100.00	181	82.87	8.84	1e-102	hypothetical protein LOC100170433 K07943 ADP-ribosylation factor-like 2
	afm:AFUA_1G14970	1	181	181	n/a	100.00	181	82.87	8.84	1e-100	ADP-ribosylation factor family protein K07943 ADP-ribosylation factor-like 2
	ncr:NCU00218	1	181	181	n/a	100.00	181	82.32	10.50	1e-100	similar to ADP-ribosylation factor family protein K07943 ADP-ribosylation factor-like 2
	aor:AO090005001232	1	181	181	n/a	100.00	181	81.77	8.29	2e-98	GTP-binding ADP-ribosylation factor-like protein ARL2 K07943 ADP-ribosylation factor-like 2
	ang:An01g13120	1	181	181	n/a	100.00	181	81.77	7.73	9e-98	hypothetical protein K07943 ADP-ribosylation factor-like 2
	fgr:FG06640.1	1	181	181	n/a	100.00	181	78.45	10.50	1e-94	hypothetical protein K07943 ADP-ribosylation factor-like 2
	pan:PODANSg4784	1	181	181	n/a	89.66	203	78.57	11.54	2e-85	hypothetical protein K07943 ADP-ribosylation factor-like 2
	xtr:394753	1	179	179	n/a	97.28	184	62.57	20.67	3e-78	arl2 ADP-ribosylation factor-like 2 K07943 ADP-ribosylation factor-like 2
	cin:100178355	1	179	179	n/a	97.28	184	60.89	22.91	5e-78	similar to ADP-ribosylation factor-like 2 K07943 ADP-ribosylation factor-like 2
	lbc:LACBIDRAFT_252312	1	179	179	n/a	90.86	197	63.69	17.32	1e-77	GTP-binding protein K07943 ADP-ribosylation factor-like 2
blastp_uniprot_sprot	sp\|Q2TA37\|ARL2_BOVIN	1	180	180	n/a	97.83	184	59.44	23.89	4e-77	ADP-ribosylation factor-like protein 2 OS Bos taurus GN ARL2 PE 2 SV 1
	sp\|P36404\|ARL2_HUMAN	1	179	179	n/a	97.28	184	59.22	23.46	3e-76	ADP-ribosylation factor-like protein 2 OS Homo sapiens GN ARL2 PE 1 SV 4
	sp\|Q9D0J4\|ARL2_MOUSE	1	179	179	n/a	97.28	184	59.22	24.02	2e-75	ADP-ribosylation factor-like protein 2 OS Mus musculus GN Arl2 PE 1 SV 1
	sp\|O08697\|ARL2_RAT	1	179	179	n/a	97.28	184	58.66	24.58	6e-75	ADP-ribosylation factor-like protein 2 OS Rattus norvegicus GN Arl2 PE 2 SV 1
	sp\|Q54UF1\|ARL2_DICDI	1	180	180	n/a	97.83	184	57.22	23.33	2e-74	ADP-ribosylation factor-like protein 2 OS Dictyostelium discoideum GN arl2 PE 3 SV 1
	sp\|Q06849\|ARL2_DROME	2	179	178	n/a	96.74	184	58.43	20.79	4e-72	ADP-ribosylation factor-like protein 2 OS Drosophila melanogaster GN Arf84F PE 2 SV 2
	sp\|Q627K4\|ARL2_CAEBR	2	180	179	n/a	97.28	184	57.54	19.55	3e-71	ADP-ribosylation factor-like protein 2 OS Caenorhabditis briggsae GN evl-20.1 PE 3 SV 1
	sp\|Q19705\|ARL2_CAEEL	2	180	179	n/a	97.28	184	55.87	20.11	3e-68	ADP-ribosylation factor-like protein 2 OS Caenorhabditis elegans GN evl-20 PE 2 SV 2
	sp\|Q9ZPX1\|ARF5_ARATH	1	180	180	n/a	95.14	185	59.09	21.02	3e-67	Probable ADP-ribosylation factor At2g18390 OS Arabidopsis thaliana GN At2g18390 PE 2 SV 1
	sp\|Q09767\|ARL_SCHPO	1	175	175	n/a	94.09	186	52.00	21.71	8e-63	ADP-ribosylation factor-like protein alp41 OS Schizosaccharomyces pombe GN alp41 PE 2 SV 1
blastp_pdb	3dof_A	1	179	179	n/a	93.23	192	59.22	23.46	5e-77	mol:protein length:192 ADP-ribosylation factor-like protein 2
	3doe_A	1	179	179	n/a	93.23	192	59.22	23.46	5e-77	mol:protein length:192 ADP-ribosylation factor-like protein 2
	1ksj_A	1	179	179	n/a	96.24	186	59.22	24.02	3e-76	mol:protein length:186 arf-like protein 2
	1ksh_A	1	179	179	n/a	96.24	186	59.22	24.02	3e-76	mol:protein length:186 arf-like protein 2
	1ksg_A	1	179	179	n/a	96.24	186	59.22	24.02	3e-76	mol:protein length:186 arf-like protein 2
	1fzq_A	12	177	166	n/a	91.71	181	48.80	23.49	1e-56	mol:protein length:181 ADP-RIBOSYLATION FACTOR-LIKE PROTEIN 3
	3bh7_A	14	173	160	n/a	97.56	164	49.38	23.12	7e-55	mol:protein length:164 ADP-ribosylation factor-like protein 3
	3bh6_A	14	173	160	n/a	97.56	164	48.75	23.12	6e-54	mol:protein length:164 ADP-ribosylation factor-like protein 3
	1moz_B	12	175	164	n/a	89.62	183	45.73	21.95	6e-48	mol:protein length:183 ADP-ribosylation factor-like protein 1
	1moz_A	12	175	164	n/a	89.62	183	45.73	21.95	6e-48	mol:protein length:183 ADP-ribosylation factor-like protein 1
rpsblast_cdd	gnl\|CDD\|133354	1	173	173	n/a	100.00	173	65.90	21.39	9e-84	cd04154 Arl2 Arl2 subfamily. Arl2 (Arf-like 2) GTPases are members of the Arf family that bind GDP and GTP with very low affinity. Unlike most Arf family proteins Arl2 is not myristoylated at its N-terminal helix. The protein PDE-delta first identified in photoreceptor rod cells binds specifically to Arl2 and is structurally very similar to RhoGDI. Despite the high structural similarity between Arl2 and Rho proteins and between PDE-delta and RhoGDI the interactions between the GTPases and their effectors are very different. In its GTP bound form Arl2 interacts with the protein Binder of Arl2 (BART) and the complex is believed to play a role in mitochondrial adenine nucleotide transport. In its GDP bound form Arl2 interacts with tubulin- folding Cofactor D this interaction is believed to play a role in regulation of microtubule dynamics that impact the cytoskeleton cell division and cytokinesis.
	gnl\|CDD\|109094	12	173	162	n/a	99.39	163	50.62	20.37	1e-64	pfam00025 Arf ADP-ribosylation factor family. Pfam combines a number of different Prosite families together.
	gnl\|CDD\|133355	1	171	171	n/a	98.84	173	52.63	21.64	4e-62	cd04155 Arl3 Arl3 subfamily. Arl3 (Arf-like 3) is an Arf family protein that differs from most Arf family members in the N-terminal extension. In is inactive GDP-bound form the N-terminal extension forms an elongated loop that is hydrophobically anchored into the membrane surface however it has been proposed that this region might form a helix in the GTP-bound form. The delta subunit of the rod-specific cyclic GMP phosphodiesterase type 6 (PDEdelta) is an Arl3 effector. Arl3 binds microtubules in a regulated manner to alter specific aspects of cytokinesis via interactions with retinitis pigmentosa 2 (RP2). It has been proposed that RP2 functions in concert with Arl3 to link the cell membrane and the cytoskeleton in photoreceptors as part of the cell signaling or vesicular transport machinery. In mice the absence of Arl3 is associated with abnormal epithelial cell proliferation and cyst formation.
	gnl\|CDD\|133254	16	172	157	n/a	99.37	158	50.96	21.02	2e-56	cd00878 Arf_Arl Arf (ADP-ribosylation factor)/Arl (Arf-like) small GTPases. Arf proteins are activators of phospholipase D isoforms. Unlike Ras proteins they lack cysteine residues at their C-termini and therefore are unlikely to be prenylated. Arfs are N-terminally myristoylated. Members of the Arf family are regulators of vesicle formation in intracellular traffic that interact reversibly with membranes of the secretory and endocytic compartments in a GTP-dependent manner. They depart from other small GTP-binding proteins by a unique structural device interswitch toggle that implements front-back communication from N-terminus to the nucleotide binding site. Arf-like (Arl) proteins are close relatives of the Arf but only Arl1 has been shown to function in membrane traffic like the Arf proteins. Arl2 has an unrelated function in the folding of native tubulin and Arl4 may function in the nucleus. Most other Arf family proteins are so far relatively poorly characterized. Thus despite their significant sequence homologies Arf family proteins may regulate unrelated functions.
	gnl\|CDD\|133353	13	172	160	n/a	91.95	174	45.00	20.62	7e-50	cd04153 Arl5_Arl8 Arl5/Arl8 subfamily. Arl5 (Arf-like 5) and Arl8 like Arl4 and Arl7 are localized to the nucleus and nucleolus. Arl5 is developmentally regulated during embryogenesis in mice. Human Arl5 interacts with the heterochromatin protein 1-alpha (HP1alpha) a nonhistone chromosomal protein that is associated with heterochromatin and telomeres and prevents telomere fusion. Arl5 may also play a role in embryonic nuclear dynamics and/or signaling cascades. Arl8 was identified from a fetal cartilage cDNA library. It is found in brain heart lung cartilage and kidney. No function has been assigned for Arl8 to date.
rpsblast_kog	gnl\|CDD\|35296	1	181	181	Gaps:1	98.38	185	60.44	21.43	2e-60	KOG0073 KOG0073 KOG0073 GTP-binding ADP-ribosylation factor-like protein ARL2 [Intracellular trafficking secretion and vesicular transport Cytoskeleton].
	gnl\|CDD\|35293	1	177	177	Gaps:2	97.79	181	47.46	18.64	3e-47	KOG0070 KOG0070 KOG0070 GTP-binding ADP-ribosylation factor Arf1 [Intracellular trafficking secretion and vesicular transport].
	gnl\|CDD\|35297	1	175	175	Gaps:2	95.68	185	42.94	22.03	4e-43	KOG0074 KOG0074 KOG0074 GTP-binding ADP-ribosylation factor-like protein ARL3 [General function prediction only].
	gnl\|CDD\|35294	13	175	163	n/a	90.56	180	42.94	21.47	7e-42	KOG0071 KOG0071 KOG0071 GTP-binding ADP-ribosylation factor Arf6 (dArf3) [Intracellular trafficking secretion and vesicular transport].
	gnl\|CDD\|35295	2	177	176	n/a	96.70	182	43.18	20.45	5e-41	KOG0072 KOG0072 KOG0072 GTP-binding ADP-ribosylation factor-like protein ARL1 [Intracellular trafficking secretion and vesicular transport].

Other analysis

Functional Gbrowse

Structural Gbrowse

Genome Mapping at gene locus

Analysis	Hit name	RefStart	RefEnd	Hit length	Hit identity	Hit coverage	eValue	Hit description
blastx_uniprot_trembl	Q0V239	149698	150195	183	89.92	65.03	n/a	Putative uncharacterized protein - Phaeosphaeria nodorum (Septoria nodorum)
	A6RUH4	149872	150605	172	77.03	86.05	n/a	Putative uncharacterized protein - Botryotinia fuckeliana (strain B05.10) (Noble rot fungus) (Botrytis cinerea)
	A6QYG8	149698	150192	181	79.66	65.19	n/a	Putative uncharacterized protein - Ajellomyces capsulata (strain NAm1) (Histoplasma capsulatum)
	Q4WRV4	149698	150192	181	77.97	65.19	n/a	ADP-ribosylation factor family protein - Aspergillus fumigatus (Sartorya fumigata)
	Q0CZN3	149698	150192	181	77.97	65.19	n/a	Putative uncharacterized protein - Aspergillus terreus (strain NIH 2624)
	Q2UQI5	149698	150192	181	77.12	65.19	n/a	GTP-binding ADP-ribosylation factor-like protein ARL2 - Aspergillus oryzae
	Q7RXK9	149698	150192	181	77.12	65.19	n/a	Putative uncharacterized protein - Neurospora crassa
	Q2H8S2	149698	150204	186	75.41	65.59	n/a	Putative uncharacterized protein - Chaetomium globosum (Soil fungus)
	A2QAX5	149698	150192	181	77.12	65.19	n/a	Contig An01c0390 complete genome - Aspergillus niger
	Q1E2B8	149698	150192	184	75.42	64.13	n/a	Putative uncharacterized protein - Coccidioides immitis
blastx_FNG31_prot	SNU01925.1	149698	150195	183	89.92	65.03	n/a	Stagonospora nodorum conserved hypothetical protein translation
	BC1G_03748.1	149872	150605	172	77.03	86.05	n/a	Botrytis cinerea conserved hypothetical protein translation 173 aa
	gi:70996222:ref:XP_752866.1:	149698	150192	181	77.97	65.19	n/a	Aspergillus fumigatus Af293 hypothetical protein Afu1g14970
	AO090005001232	149698	150192	181	77.12	65.19	n/a	Aspergillus oryzae GTP-binding ADP-ribosylation factor-like protein ARL2
	CHG03382.1	149698	150204	186	75.41	65.59	n/a	Chaetomium globosum conserved hypothetical protein translation 187 aa
	CIMG_03295.2	149698	150192	184	75.42	64.13	n/a	Coccidioides immitis hypothetical protein translation 185 aa
	jgi:Triree:29890	149698	150192	181	70.34	65.19	n/a	Trichoderma reesei
	FG06640.1	149698	150192	181	71.19	65.19	n/a	fusarium_graminearum conserved hypothetical protein 182 aa
	gi:58261900:ref:XP_568360.1	149704	150195	195	58.12	60.00	n/a	Cryptococcus neoformans var. neoformans JEC21 ADP-ribosylation-like factor
	jgi:Phchr1:139806:e_gww2.2.894	149704	150192	218	58.62	53.21	n/a	Phanerochaete chrysosporium
blat_BES	no results
blastx_SN15proteins	gnl:WGS:AAGI:SNOT_01925.1:gb:EAT90137	149698	150195	183	89.92	65.03	n/a	n/a
RepeatMasker_SR	no results
RepeatMasker_LC	no results
sim4_Lm_allest	RS0AAG6YB19CM1	149658	149780	123	100.00	100.00	n/a	Lm isolate JN3 - Ungerminated conidia (V8 agar) (insert up to 1kb)
sim4_lm_allest6_clctg	RS0AAG6YB19CM1	149658	149780	123	100.00	100.00	n/a	Lm isolate JN3 - Ungerminated conidia (V8 agar) (insert up to 1kb)
sim4_cDNA_BHowlett	no results
blastx_uniprot_sprot	Q2TA37	149701	150192	184	57.26	63.59	n/a	ADP-ribosylation factor-like protein 2 - Bos taurus (Bovine)
	P36404	149704	150192	184	57.76	63.04	n/a	ADP-ribosylation factor-like protein 2 - Homo sapiens (Human)
	O08697	149704	150192	184	56.03	63.04	n/a	ADP-ribosylation factor-like protein 2 - Rattus norvegicus (Rat)
	Q9D0J4	149704	150192	184	56.03	63.04	n/a	ADP-ribosylation factor-like protein 2 - Mus musculus (Mouse)
	Q627K4	149701	150192	184	58.97	63.59	n/a	ADP-ribosylation factor-like protein 2 - Caenorhabditis briggsae
REPET	no results
MUMer_show_coords_lm_WA74	no results