GRS - Genome Report System

Leptosphaeria maculans GRS

Functional annotation

Lema_P085720.1

Gene Identifier

DbXrefs

Domain/Motif (Interproscan results)

Localization / Targeting

Predicted function

Blast based analysis

Analysis	Hit	start	end	length	Note	Hit coverage	Hit length	Hit pident	Hit pcons	eValue	Hit description
blastp_kegg	fgr:FG07783.1	4	436	433	n/a	82.90	503	62.35	16.79	1e-173	hypothetical protein
	ssl:SS1G_07280	18	433	416	n/a	81.68	475	63.40	13.92	1e-155	hypothetical protein
	bfu:BC1G_14811	18	433	416	n/a	78.32	475	62.10	13.17	1e-144	hypothetical protein
	ang:An03g05930	22	433	412	n/a	82.05	440	43.77	19.94	2e-78	hypothetical protein
	bfu:BC1G_11751	22	436	415	n/a	78.76	452	42.70	20.51	3e-74	hypothetical protein
	ssl:SS1G_07022	22	433	412	n/a	77.92	453	42.49	20.68	8e-74	hypothetical protein
	afm:AFUA_8G01910	24	433	410	n/a	78.22	427	45.21	18.26	9e-71	histidine acid phosphatase (EC:3.1.3.2) K01078 acid phosphatase [EC:3.1.3.2]
	fgr:FG03402.1	19	433	415	n/a	74.40	457	40.88	24.12	9e-71	hypothetical protein
	aor:AO090011000174	23	433	411	n/a	77.01	448	42.03	22.03	2e-69	multiple inositol polyphosphate phosphatase
	nfi:NFIA_095520	24	433	410	n/a	76.71	425	43.56	19.94	2e-68	histidine acid phosphatase putative
blastp_uniprot_sprot	sp\|P34755\|PHYB_ASPAW	27	421	395	n/a	36.74	479	30.68	20.45	4e-18	3-phytase B OS Aspergillus awamori GN phyB PE 1 SV 1
	sp\|P34754\|PHYB_ASPNG	27	421	395	n/a	29.65	479	35.21	19.01	3e-16	3-phytase B OS Aspergillus niger GN phyB PE 1 SV 1
	sp\|O60172\|PPA3_SCHPO	29	409	381	n/a	39.31	463	32.97	21.98	2e-13	Thiamine-repressible acid phosphatase SPBC21H7.03c OS Schizosaccharomyces pombe GN SPBC21H7.03c PE 2 SV 1
	sp\|P52291\|PPA1_PICPA	14	415	402	n/a	44.87	468	32.38	20.48	1e-11	Acid phosphatase PHO1 OS Pichia pastoris GN PHO1 PE 2 SV 1
	sp\|P52289\|PPA5_KLULA	42	419	378	n/a	33.05	469	31.61	18.71	2e-11	Repressible acid phosphatase OS Kluyveromyces lactis GN PHO5 PE 2 SV 2
	sp\|Q01682\|PPA2_SCHPO	29	409	381	n/a	39.31	463	32.97	19.23	3e-11	Thiamine-repressible acid phosphatase pho4 OS Schizosaccharomyces pombe GN pho4 PE 1 SV 1
blastp_pdb	1qfx_B	27	421	395	n/a	38.26	460	30.68	20.45	7e-19	mol:protein length:460 PROTEIN (PH 2.5 ACID PHOSPHATASE)
	1qfx_A	27	421	395	n/a	38.26	460	30.68	20.45	7e-19	mol:protein length:460 PROTEIN (PH 2.5 ACID PHOSPHATASE)
	2gfi_B	4	421	418	n/a	35.59	458	28.83	19.02	3e-13	mol:protein length:458 phytase
	2gfi_A	4	421	418	n/a	35.59	458	28.83	19.02	3e-13	mol:protein length:458 phytase
rpsblast_cdd	gnl\|CDD\|132717	113	393	281	Gaps:75	92.56	242	32.14	13.39	2e-26	cd07061 HP_HAP_like Histidine phosphatase domain found in histidine acid phosphatases and phytases contains a His residue which is phosphorylated during the reaction. Catalytic domain of HAP (histidine acid phosphatases) and phytases (myo-inositol hexakisphosphate phosphohydrolases). The conserved catalytic core of this domain contains a His residue which is phosphorylated in the reaction. Functions in this subgroup include roles in metabolism signaling or regulation for example Escherichia coli glucose-1-phosphatase functions to scavenge glucose from glucose-1-phosphate and the signaling molecules inositol 1 3 4 5 6-pentakisphosphate (InsP5) and inositol hexakisphosphate (InsP6) are in vivo substrates for eukaryotic multiple inositol polyphosphate phosphatase 1 (Minpp1). Phytases scavenge phosphate from extracellular sources and are added to animal feed while prostatic acid phosphatase (PAP) has been used for many years as a serum marker for prostate cancer. Recently PAP has been shown in mouse models to suppress pain by functioning as an ecto-5prime-nucleotidase. In vivo it dephosphorylates extracellular adenosine monophosphate (AMP) generating adenosine and leading to the activation of A1-adenosine receptors in dorsal spinal cord.
	gnl\|CDD\|109388	60	393	334	Gaps:61	97.88	330	23.22	15.79	9e-26	pfam00328 Acid_phosphat_A Histidine acid phosphatase.
	gnl\|CDD\|132716	59	170	112	Gaps:35	50.33	153	31.17	14.29	9e-04	cd07040 HP Histidine phosphatase domain found in a functionally diverse set of proteins mostly phosphatases contains a His residue which is phosphorylated during the reaction. Catalytic domain of a functionally diverse set of proteins most of which are phosphatases. The conserved catalytic core of this domain contains a His residue which is phosphorylated in the reaction. This set of proteins includes cofactor-dependent and cofactor-independent phosphoglycerate mutases (dPGM and BPGM respectively) fructose-2 6-bisphosphatase (F26BP)ase Sts-1 SixA histidine acid phosphatases phytases and related proteins. Functions include roles in metabolism signaling or regulation for example F26BPase affects glycolysis and gluconeogenesis through controlling the concentration of F26BP BPGM controls the concentration of 2 3-BPG (the main allosteric effector of hemoglobin in human blood cells) human Sts-1 is a T-cell regulator Escherichia coli Six A participates in the ArcB-dependent His-to-Asp phosphorelay signaling system phytases scavenge phosphate from extracellular sources. Deficiency and mutation in many of the human members result in disease for example erythrocyte BPGM deficiency is a disease associated with a decrease in the concentration of 2 3-BPG. Clinical applications include the use of prostatic acid phosphatase (PAP) as a serum marker for prostate cancer. Agricultural applications include the addition of phytases to animal feed.
	gnl\|CDD\|32245	101	168	68	Gaps:4	39.26	163	21.88	14.06	1.3	COG2062 SixA Phosphohistidine phosphatase SixA [Signal transduction mechanisms].
	gnl\|CDD\|113743	247	275	29	n/a	6.74	430	31.03	17.24	1.9	pfam04984 Phage_sheath_1 Phage tail sheath protein. This family includes a variety of phage tail sheath proteins.
rpsblast_kog	gnl\|CDD\|36596	3	417	415	Gaps:53	89.08	467	26.44	11.78	8e-34	KOG1382 KOG1382 KOG1382 Multiple inositol polyphosphate phosphatase [General function prediction only].
	gnl\|CDD\|38876	113	166	54	Gaps:9	12.94	487	26.98	15.87	0.11	KOG3672 KOG3672 KOG3672 Histidine acid phosphatase [General function prediction only].
	gnl\|CDD\|35728	51	83	33	Gaps:2	5.04	615	38.71	19.35	2.8	KOG0508 KOG0508 KOG0508 Ankyrin repeat protein [General function prediction only].
	gnl\|CDD\|36231	371	418	48	n/a	13.26	362	20.83	8.33	3.4	KOG1013 KOG1013 KOG1013 Synaptic vesicle protein rabphilin-3A [Intracellular trafficking secretion and vesicular transport].
	gnl\|CDD\|37176	319	379	61	Gaps:3	10.78	575	32.26	3.23	9.4	KOG1965 KOG1965 KOG1965 Sodium/hydrogen exchanger protein [Inorganic ion transport and metabolism].

Other analysis

Functional Gbrowse

Structural Gbrowse

Genome Mapping at gene locus

Analysis	Hit name	RefStart	RefEnd	Hit length	Hit identity	Hit coverage	eValue	Hit description
blastx_uniprot_trembl	A7EPN1	1235288	1236628	475	56.68	97.68	n/a	Putative uncharacterized protein - Sclerotinia sclerotiorum (strain ATCC 18683 / 1980 / Ss-1) (White mold) (Whetzelinia sclerotiorum)
	A6SPC2	1235288	1236628	475	57.11	97.68	n/a	Putative uncharacterized protein - Botryotinia fuckeliana (strain B05.10) (Noble rot fungus) (Botrytis cinerea)
	Q0UQN4	1235498	1238338	820	78.06	95.61	n/a	Putative uncharacterized protein - Phaeosphaeria nodorum (Septoria nodorum)
blastx_FNG31_prot	BC1G_11751.1	1235381	1236637	452	38.77	93.58	n/a	Botrytis cinerea hypothetical protein translation 453 aa
	AO090011000174	1235396	1236628	448	38.16	92.41	n/a	Aspergillus oryzae multiple inositol polyphosphate phosphatase
	SNU05929.1	1235300	1236637	455	75.34	97.14	n/a	Stagonospora nodorum hypothetical protein translation
	FG07783.1	1235312	1236637	503	58.68	90.46	n/a	fusarium_graminearum hypothetical protein 504 aa
	SS1G_07280.1	1235288	1236628	475	56.68	97.68	n/a	sclerotinia_sclerotiorum hypothetical protein translation 476 aa
	BC1G_14811.1	1235288	1236628	475	57.11	97.68	n/a	Botrytis cinerea hypothetical protein translation 476 aa
	SS1G_07022.1	1235381	1236661	453	38.11	95.58	n/a	sclerotinia_sclerotiorum hypothetical protein translation 454 aa
	SNU00343.1	1235339	1236676	440	38.04	99.77	n/a	Stagonospora nodorum predicted protein translation
	FG03402.1	1235384	1236661	457	35.83	93.44	n/a	fusarium_graminearum hypothetical protein 458 aa
	MGG_09199.5	1235288	1236673	473	36.20	95.77	n/a	magnaporthe_grisea hypothetical protein translation 474 aa
blat_BES	QS0AAE109ZD05FM1	1236284	1236838	935	n/a	n/a	n/a	n/a
blastx_SN15proteins	gnl:WGS:AAGI:SNOT_12840.2:gb:EAT79640	1235456	1236634	477	25.92	85.74	n/a	n/a
	gnl:WGS:AAGI:SNOT_07594.2:gb:EAT85060	1235576	1236637	388	28.49	90.46	n/a	n/a
	gnl:WGS:AAGI:SNOT_05930.2:gb:EAT86994	1235498	1238338	820	78.06	95.61	n/a	n/a
	gnl:WGS:AAGI:SNOT_00343.2:gb:EAT91838	1235339	1236676	440	38.04	99.77	n/a	n/a
RepeatMasker_SR	no results
RepeatMasker_LC	no results
sim4_Lm_allest	no results
sim4_lm_allest6_clctg	no results
sim4_cDNA_BHowlett	no results
blastx_uniprot_sprot	P52289	1235390	1236586	469	26.79	83.58	n/a	Repressible acid phosphatase precursor - Kluyveromyces lactis (Yeast) (Candida sphaerica)
	P52291	1235369	1236628	468	25.06	88.68	n/a	Acid phosphatase PHO1 precursor - Pichia pastoris (Yeast)
	Q9C1T1	1235399	1236574	466	27.14	87.77	n/a	3-phytase A precursor - Aspergillus oryzae
	O60172	1235366	1236556	463	25.44	86.61	n/a	Thiamine-repressible acid phosphatase SPBC21H7.03c precursor - Schizosaccharomyces pombe (Fission yeast)
	P34754	1235285	1236592	479	26.64	89.35	n/a	3-phytase B precursor - Aspergillus niger
	P34755	1235285	1236592	479	26.17	89.35	n/a	3-phytase B precursor - Aspergillus awamori
	Q0CLV1	1235321	1236451	466	26.32	85.62	n/a	3-phytase A precursor - Aspergillus terreus (strain NIH 2624)
	O00085	1235321	1236451	466	26.32	85.62	n/a	3-phytase A precursor - Aspergillus terreus
REPET	no results
MUMer_show_coords_lm_WA74	no results