GRS - Genome Report System

Leptosphaeria maculans GRS

Functional annotation

Lema_P058280.1

Gene Identifier

DbXrefs

Domain/Motif (Interproscan results)

Localization / Targeting

Predicted function

Blast based analysis

Analysis	Hit	start	end	length	Note	Hit coverage	Hit length	Hit pident	Hit pcons	eValue	Hit description
blastp_kegg	nfi:NFIA_086310	384	793	410	n/a	77.21	531	59.76	11.22	1e-163	dihydroorotate reductase PyrE putative K00226 dihydroorotate oxidase [EC:1.3.3.1]
	afm:AFUA_2G11010	384	793	410	n/a	77.21	531	59.76	11.46	1e-163	dihydroorotate reductase PyrE (EC:1.3.3.-) K05897
	ang:An02g02910	387	774	388	n/a	71.32	544	62.11	12.89	1e-160	hypothetical protein K00226 dihydroorotate oxidase [EC:1.3.3.1]
	ani:AN5909.2	407	774	368	n/a	70.77	520	64.40	11.68	1e-157	similar to S72324 orotate reductase (NADH2) (EC 1.3.1.14) - Emericella nidulans K00226 dihydroorotate oxidase [EC:1.3.3.1]
	aor:AO090026000542	380	791	412	n/a	78.48	525	58.50	11.89	1e-155	dihydroorotate dehydrogenase K00226 dihydroorotate oxidase [EC:1.3.3.1]
	ncr:NCU06532	391	774	384	n/a	76.20	500	58.01	11.29	1e-135	similar to dihydroorotate reductase PyrE K00226 dihydroorotate oxidase [EC:1.3.3.1]
	ssl:SS1G_14024	463	788	326	n/a	80.44	409	63.53	13.98	1e-130	hypothetical protein K00226 dihydroorotate oxidase [EC:1.3.3.1]
	pan:PODANSg7756	408	774	367	n/a	73.86	482	61.24	11.52	1e-129	hypothetical protein K00226 dihydroorotate oxidase [EC:1.3.3.1]
	fgr:FG09678.1	400	775	376	n/a	78.39	472	56.49	11.08	1e-126	hypothetical protein K00226 dihydroorotate oxidase [EC:1.3.3.1]
	mgr:MGG_08814	440	735	296	n/a	55.06	514	59.36	12.01	2e-94	hypothetical protein K00226 dihydroorotate oxidase [EC:1.3.3.1]
blastp_uniprot_sprot	sp\|Q6V3W9\|PYRD_SACKL	424	733	310	n/a	55.38	446	51.42	16.60	8e-54	Dihydroorotate dehydrogenase mitochondrial OS Saccharomyces kluyveri GN URA9 PE 1 SV 1
	sp\|Q6SZS5\|PYRD_CANGA	420	733	314	n/a	57.63	439	49.80	17.00	5e-53	Dihydroorotate dehydrogenase mitochondrial OS Candida glabrata GN URA9 PE 3 SV 1
	sp\|Q6SZS6\|PYRD2_KLUMA	432	733	302	n/a	49.10	446	54.34	14.61	1e-49	Dihydroorotate dehydrogenase mitochondrial OS Kluyveromyces marxianus GN URA9 PE 3 SV 1
	sp\|Q6CTX8\|PYRD2_KLULA	427	733	307	n/a	50.34	445	50.45	16.96	2e-47	Dihydroorotate dehydrogenase mitochondrial OS Kluyveromyces lactis GN URA9 PE 3 SV 1
	sp\|Q75CE1\|PYRD_ASHGO	413	733	321	n/a	50.90	444	47.79	15.04	4e-45	Dihydroorotate dehydrogenase mitochondrial OS Ashbya gossypii GN URA9 PE 3 SV 1
	sp\|P32747\|PYRD_SCHPO	489	733	245	n/a	48.08	443	46.48	19.72	3e-43	Dihydroorotate dehydrogenase mitochondrial OS Schizosaccharomyces pombe GN ura3 PE 1 SV 1
	sp\|Q874I4\|PYRD_CANAL	429	730	302	n/a	49.55	444	49.55	15.91	2e-42	Dihydroorotate dehydrogenase mitochondrial OS Candida albicans GN URA9 PE 1 SV 1
	sp\|Q02127\|PYRD_HUMAN	489	730	242	n/a	47.09	395	51.61	15.05	5e-42	Dihydroorotate dehydrogenase mitochondrial OS Homo sapiens GN DHODH PE 1 SV 3
	sp\|Q63707\|PYRD_RAT	489	730	242	n/a	48.35	395	50.79	13.09	1e-41	Dihydroorotate dehydrogenase mitochondrial OS Rattus norvegicus GN Dhodh PE 1 SV 1
	sp\|Q5R6X6\|PYRD_PONAB	489	730	242	n/a	47.09	395	51.08	14.52	6e-41	Dihydroorotate dehydrogenase mitochondrial OS Pongo abelii GN DHODH PE 2 SV 1
blastp_pdb	3g0x_A	489	730	242	n/a	50.68	367	51.61	15.05	9e-43	mol:protein length:367 Dihydroorotate dehydrogenase
	3g0u_A	489	730	242	n/a	50.68	367	51.61	15.05	9e-43	mol:protein length:367 Dihydroorotate dehydrogenase
	3fjl_A	489	730	242	n/a	50.68	367	51.61	15.05	9e-43	mol:protein length:367 Dihydroorotate dehydrogenase
	3fj6_A	489	730	242	n/a	50.68	367	51.61	15.05	9e-43	mol:protein length:367 Dihydroorotate dehydrogenase
	3f1q_A	489	730	242	n/a	50.68	367	51.61	15.05	9e-43	mol:protein length:367 Dihydroorotate dehydrogenase
	2prm_A	489	730	242	n/a	50.68	367	51.61	15.05	9e-43	mol:protein length:367 Dihydroorotate dehydrogenase mitochondrial
	2prl_A	489	730	242	n/a	50.68	367	51.61	15.05	9e-43	mol:protein length:367 Dihydroorotate dehydrogenase mitochondrial
	2prh_A	489	730	242	n/a	50.68	367	51.61	15.05	9e-43	mol:protein length:367 Dihydroorotate dehydrogenase mitochondrial
	2bxv_A	489	730	242	n/a	50.68	367	51.61	15.05	9e-43	mol:protein length:367 DIHYDROOROTATE DEHYDROGENASE
	1d3h_A	489	730	242	n/a	50.68	367	51.61	15.05	9e-43	mol:protein length:367 DIHYDROOROTATE DEHYDROGENASE
rpsblast_cdd	gnl\|CDD\|73400	447	774	328	Gaps:53	84.71	327	45.85	11.91	5e-71	cd04738 DHOD_2_like Dihydroorotate dehydrogenase (DHOD) class 2. DHOD catalyzes the oxidation of (S)-dihydroorotate to orotate. This is the fourth step and the only redox reaction in the de novo biosynthesis of UMP the precursor of all pyrimidine nucleotides. DHOD requires FMN as co-factor. DHOD divides into class 1 and class 2 based on their amino acid sequences their cellular location and their natural electron acceptor used to reoxidize the flavin group. Members of class 1 are cytosolic enzymes and multimers while class 2 enzymes are membrane associated monomeric and use respiratory quinones as their physiological electron acceptors..
	gnl\|CDD\|135296	444	774	331	Gaps:52	83.04	336	41.94	15.05	4e-65	PRK05286 PRK05286 dihydroorotate dehydrogenase 2 Reviewed.
	gnl\|CDD\|130108	455	756	302	Gaps:45	76.72	335	38.91	14.01	1e-46	TIGR01036 pyrD_sub2 The subfamilies 1 and 2 share extensive homology particularly toward the C-terminus. This subfamily has a longer N-terminal region.
	gnl\|CDD\|30516	488	774	287	Gaps:50	77.10	310	38.49	13.39	2e-41	COG0167 PyrD Dihydroorotate dehydrogenase [Nucleotide transport and metabolism].
	gnl\|CDD\|110199	489	774	286	Gaps:52	81.38	290	34.75	15.68	7e-41	pfam01180 DHO_dh Dihydroorotate dehydrogenase.
rpsblast_kog	gnl\|CDD\|36649	402	774	373	Gaps:47	81.91	398	40.49	12.58	3e-54	KOG1436 KOG1436 KOG1436 Dihydroorotate dehydrogenase [Nucleotide transport and metabolism].
	gnl\|CDD\|39841	10	313	304	Gaps:32	96.48	284	35.40	19.34	1e-34	KOG4642 KOG4642 KOG4642 Chaperone-dependent E3 ubiquitin protein ligase (contains TPR repeats) [Posttranslational modification protein turnover chaperones].
	gnl\|CDD\|35767	10	82	73	n/a	12.05	606	39.73	19.18	4e-12	KOG0547 KOG0547 KOG0547 Translocase of outer mitochondrial membrane complex subunit TOM70/TOM72 [Intracellular trafficking secretion and vesicular transport].
	gnl\|CDD\|39435	10	80	71	Gaps:5	28.04	271	42.11	19.74	3e-10	KOG4234 KOG4234 KOG4234 TPR repeat-containing protein [General function prediction only].
	gnl\|CDD\|35768	6	83	78	Gaps:1	48.98	539	32.20	24.24	8e-10	KOG0548 KOG0548 KOG0548 Molecular co-chaperone STI1 [Posttranslational modification protein turnover chaperones].

Other analysis

Functional Gbrowse

Structural Gbrowse

Genome Mapping at gene locus

Analysis	Hit name	RefStart	RefEnd	Hit length	Hit identity	Hit coverage	eValue	Hit description
blastx_uniprot_trembl	Q0U3T7	615397	616410	291	85.22	100.00	n/a	Putative uncharacterized protein - Phaeosphaeria nodorum (Septoria nodorum)
	A2QCB4	615424	616410	284	42.40	99.65	n/a	Contig An02c0080 complete genome - Aspergillus niger
	Q2H1V1	615742	616410	285	40.36	78.25	n/a	Putative uncharacterized protein - Chaetomium globosum (Soil fungus)
	Q1DP29	615790	616410	284	40.20	71.83	n/a	Putative uncharacterized protein - Coccidioides immitis
	A6RGG6	615790	616410	284	40.20	71.83	n/a	Putative uncharacterized protein - Ajellomyces capsulata (strain NAm1) (Histoplasma capsulatum)
	A1DH22	615790	616410	284	39.71	71.83	n/a	U-box domain protein - Neosartorya fischeri (strain ATCC 1020 / DSM 3700 / NRRL 181) (Aspergillus fischerianus (strain ATCC 1020 / DSM 3700 / NRRL 181))
	Q4X166	615790	616410	284	39.71	71.83	n/a	U-box domain protein putative - Aspergillus fumigatus (Sartorya fumigata)
	A1C6E9	615790	616410	284	38.24	71.83	n/a	U-box domain protein - Aspergillus clavatus
	Q2UEN9	615790	616410	267	39.71	76.40	n/a	Chaperone-dependent E3 ubiquitin protein ligase - Aspergillus oryzae
	Q0CXV9	615790	616410	285	38.73	71.58	n/a	Putative uncharacterized protein - Aspergillus terreus (strain NIH 2624)
	A1DH19	617116	618438	531	58.31	82.67	n/a	Dihydroorotate reductase PyrE putative - Neosartorya fischeri (strain ATCC 1020 / DSM 3700 / NRRL 181) (Aspergillus fischerianus (strain ATCC 1020 / DSM 3700 / NRRL 181))
	Q4X169	617116	618438	531	58.31	82.67	n/a	Dihydroorotate reductase PyrE putative - Aspergillus fumigatus (Sartorya fumigata)
	Q1DP22	617134	618399	523	59.48	80.69	n/a	Putative uncharacterized protein - Coccidioides immitis
	Q12610	617137	618375	520	60.72	79.81	n/a	Dihydroorotate dehydrogenase - Emericella nidulans (Aspergillus nidulans)
	A2QCB1	617125	618288	544	62.11	71.32	n/a	Catalytic activity: - Aspergillus niger
	Q2UEP2	617128	618411	525	57.65	80.95	n/a	Dihydroorotate dehydrogenase - Aspergillus oryzae
	A1C6E6	617128	618402	516	58.80	80.43	n/a	Dihydroorotate reductase PyrE putative - Aspergillus clavatus
	A6RGH4	617194	618387	526	59.60	75.29	n/a	Putative uncharacterized protein - Ajellomyces capsulata (strain NAm1) (Histoplasma capsulatum)
	Q7S895	617125	618288	500	57.73	77.60	n/a	Putative uncharacterized protein - Neurospora crassa
	Q0U3T7	615397	616410	291	85.22	100.00	n/a	Putative uncharacterized protein - Phaeosphaeria nodorum (Septoria nodorum)
	Q0U3U0	617038	618522	549	78.20	86.89	n/a	Putative uncharacterized protein - Phaeosphaeria nodorum (Septoria nodorum)
blastx_FNG31_prot	SNU13577.1	615397	616410	291	85.22	100.00	n/a	Stagonospora nodorum predicted protein translation
	jgi:Triree:9800	615724	616410	268	45.50	78.73	n/a	Trichoderma reesei
	CHG04245.1	615742	616410	285	40.36	78.25	n/a	Chaetomium globosum hypothetical protein translation 286 aa
	CIMG_07934.2	615790	616410	284	40.20	71.83	n/a	Coccidioides immitis hypothetical protein translation 285 aa
	gi:71001512:ref:XP_755437.1:	615790	616410	284	39.71	71.83	n/a	Aspergillus fumigatus Af293 hypothetical protein Afu2g11040
	FG09672.1	615742	616410	289	43.75	71.97	n/a	fusarium_graminearum hypothetical protein 290 aa
	AO090026000545	615790	616410	267	39.71	76.40	n/a	Aspergillus oryzae chaperone-dependent E3 ubiquitin protein ligase contains TPR repeats
	AN5906	615790	616410	293	38.50	72.70	n/a	Aspergillus nidulans AN5906.3 conserved hypothetical protein translation 294 aa
	NCU10270.2	615790	616410	238	41.18	85.71	n/a	Neurospora crassa hypothetical protein translation 239 aa
	MGG_08035.5	615796	616410	284	41.24	68.31	n/a	magnaporthe_grisea hypothetical protein translation 285 aa
	gi:71001506:ref:XP_755434.1:	617116	618438	531	58.31	82.67	n/a	Aspergillus fumigatus Af293 dihydroorotate reductase PyrE
	CIMG_07941.2	617134	618399	523	59.48	80.69	n/a	Coccidioides immitis hypothetical protein translation 524 aa
	AN5909	617137	618375	520	60.72	79.81	n/a	Aspergillus nidulans AN5909.3 hypothetical protein similar to orotate reductase translation 521 aa
	AO090026000542	617128	618411	525	57.65	80.95	n/a	Aspergillus oryzae dihydroorotate dehydrogenase
	NCU06532.2	617125	618288	500	57.73	77.60	n/a	Neurospora crassa hypothetical protein translation 501 aa
	SS1G_14024.1	617353	618378	409	61.71	85.57	n/a	sclerotinia_sclerotiorum hypothetical protein translation 410 aa
	FG09678.1	617065	618291	472	54.25	84.75	n/a	fusarium_graminearum hypothetical protein 473 aa
	jgi:Triree:9969	617194	618297	421	56.20	86.22	n/a	Trichoderma reesei
	MGG_08814.5	617059	618363	514	51.52	83.46	n/a	magnaporthe_grisea hypothetical protein translation 515 aa
	SNU13577.1	615397	616410	291	85.22	100.00	n/a	Stagonospora nodorum predicted protein translation
	SNU13574.1	617038	618522	549	78.20	86.89	n/a	Stagonospora nodorum hypothetical protein translation
blat_BES	QS0AAE104ZF12RM1	616856	617471	750	n/a	n/a	n/a	n/a
blastx_SN15proteins	gnl:WGS:AAGI:SNOT_13577.2:gb:EAT79024	615397	616410	291	85.22	100.00	n/a	n/a
	gnl:WGS:AAGI:SNOT_13577.2:gb:EAT79024	615397	616410	291	85.22	100.00	n/a	n/a
	gnl:WGS:AAGI:SNOT_13574.2:gb:EAT79021	617038	618522	549	78.20	86.89	n/a	n/a
RepeatMasker_SR	(TGG)n	616462	616497	180	n/a	n/a	n/a	n/a
RepeatMasker_LC	no results
sim4_Lm_allest	no results
sim4_lm_allest6_clctg	no results
sim4_cDNA_BHowlett	no results
blastx_uniprot_sprot	Q9UNE7	615742	616410	303	32.11	71.95	n/a	STIP1 homology and U box-containing protein 1 - Homo sapiens (Human)
	Q9WUD1	615688	616410	304	30.64	77.30	n/a	STIP1 homology and U box-containing protein 1 - Mus musculus (Mouse)
	Q5ZHY5	615742	616410	314	29.68	69.75	n/a	STIP1 homology and U box-containing protein 1 - Gallus gallus (Chicken)
	Q6V3W9	617095	618288	446	42.25	83.86	n/a	Dihydroorotate dehydrogenase mitochondrial precursor - Saccharomyces kluyveri (Yeast) (Saccharomyces silvestris)
	Q6SZS6	617182	618231	446	45.12	73.54	n/a	Dihydroorotate dehydrogenase mitochondrial precursor - Kluyveromyces marxianus (Yeast) (Candida kefyr)
	Q874I4	617212	618279	444	42.22	75.23	n/a	Dihydroorotate dehydrogenase mitochondrial precursor - Candida albicans (Yeast)
	Q6CTX8	617182	618279	445	41.62	77.75	n/a	Dihydroorotate dehydrogenase mitochondrial precursor - Kluyveromyces lactis (Yeast) (Candida sphaerica)
	Q6SZS5	617224	618288	439	42.39	76.31	n/a	Dihydroorotate dehydrogenase mitochondrial precursor - Candida glabrata (Yeast) (Torulopsis glabrata)
	Q75CE1	617089	618231	444	41.67	78.38	n/a	Dihydroorotate dehydrogenase mitochondrial precursor - Ashbya gossypii (Yeast) (Eremothecium gossypii)
	P32747	617263	618285	443	40.50	72.46	n/a	Dihydroorotate dehydrogenase mitochondrial precursor - Schizosaccharomyces pombe (Fission yeast)
	Q02127	617239	618294	395	45.57	77.22	n/a	Dihydroorotate dehydrogenase mitochondrial precursor - Homo sapiens (Human)
	O35435	617239	618156	395	46.84	68.10	n/a	Dihydroorotate dehydrogenase mitochondrial precursor - Mus musculus (Mouse)
	Q63707	617239	618156	395	46.84	68.10	n/a	Dihydroorotate dehydrogenase mitochondrial precursor - Rattus norvegicus (Rat)
REPET	no results
MUMer_show_coords_lm_WA74	no results