GRS - Genome Report System

Leptosphaeria maculans GRS

Functional annotation

Lema_P046800.1

Gene Identifier

DbXrefs

Domain/Motif (Interproscan results)

Localization / Targeting

Predicted function

Blast based analysis

Analysis	Hit	start	end	length	Note	Hit coverage	Hit length	Hit pident	Hit pcons	eValue	Hit description
blastp_kegg	ssl:SS1G_10238	225	913	689	n/a	93.74	735	68.51	13.64	0.0	hypothetical protein K00232 acyl-CoA oxidase [EC:1.3.3.6]
	bfu:BC1G_08482	225	913	689	n/a	98.42	698	68.70	13.68	0.0	hypothetical protein K00232 acyl-CoA oxidase [EC:1.3.3.6]
	aor:AO090005000479	225	907	683	n/a	98.13	694	65.93	15.86	0.0	acyl-CoA oxidase K00232 acyl-CoA oxidase [EC:1.3.3.6]
	nfi:NFIA_027340	225	914	690	n/a	99.28	692	65.79	14.70	0.0	acyl-CoA oxidase K00232 acyl-CoA oxidase [EC:1.3.3.6]
	fgr:FG02287.1	222	908	687	n/a	97.84	696	66.08	13.66	0.0	hypothetical protein K00232 acyl-CoA oxidase [EC:1.3.3.6]
	uma:UM02208.1	222	882	661	n/a	86.48	688	51.43	19.16	0.0	hypothetical protein
	afm:AFUA_7G06090	468	914	447	n/a	100.00	444	65.54	13.96	0.0	fatty-acyl coenzyme A oxidase (Pox1) (EC:1.3.3.6) K00232 acyl-CoA oxidase [EC:1.3.3.6]
	ani:AN6752.2	225	913	689	n/a	98.85	696	63.08	15.70	1e-176	hypothetical protein K00232 acyl-CoA oxidase [EC:1.3.3.6]
	ani:AN6765.2	225	907	683	n/a	87.91	695	49.59	16.86	1e-167	hypothetical protein
	aor:AO090026000762	217	907	691	n/a	52.50	981	51.07	17.86	1e-143	acyl-CoA oxidase
blastp_uniprot_sprot	sp\|P07872\|ACOX1_RAT	332	882	551	n/a	62.78	661	48.43	18.31	1e-103	Peroxisomal acyl-coenzyme A oxidase 1 OS Rattus norvegicus GN Acox1 PE 1 SV 1
	sp\|Q9ZQP2\|ACO12_ARATH	265	885	621	n/a	68.22	664	44.37	19.21	1e-101	Putative peroxisomal acyl-coenzyme A oxidase 1.2 OS Arabidopsis thaliana GN ACX1.2 PE 2 SV 1
	sp\|Q9R0H0\|ACOX1_MOUSE	332	882	551	n/a	62.78	661	47.95	18.31	1e-101	Peroxisomal acyl-coenzyme A oxidase 1 OS Mus musculus GN Acox1 PE 1 SV 4
	sp\|Q3SZP5\|ACOX1_BOVIN	326	882	557	n/a	64.09	660	46.81	17.97	2e-99	Peroxisomal acyl-coenzyme A oxidase 1 OS Bos taurus GN ACOX1 PE 2 SV 1
	sp\|Q5RC19\|ACOX1_PONAB	326	882	557	n/a	63.94	660	47.39	18.25	2e-99	Peroxisomal acyl-coenzyme A oxidase 1 OS Pongo abelii GN ACOX1 PE 2 SV 2
	sp\|Q9Z1N0\|ACOX1_CAVPO	332	882	551	n/a	62.93	661	47.60	17.31	2e-99	Peroxisomal acyl-coenzyme A oxidase 1 OS Cavia porcellus GN ACOX1 PE 2 SV 1
	sp\|Q15067\|ACOX1_HUMAN	326	882	557	n/a	63.94	660	47.39	18.25	4e-99	Peroxisomal acyl-coenzyme A oxidase 1 OS Homo sapiens GN ACOX1 PE 1 SV 3
	sp\|O65202\|ACOX1_ARATH	327	901	575	n/a	62.95	664	47.13	18.66	5e-99	Peroxisomal acyl-coenzyme A oxidase 1 OS Arabidopsis thaliana GN ACX1 PE 1 SV 1
	sp\|Q8HYL8\|ACOX1_PHACI	328	882	555	n/a	62.18	661	47.20	17.27	2e-97	Peroxisomal acyl-coenzyme A oxidase 1 OS Phascolarctos cinereus GN ACOX1 PE 1 SV 1
	sp\|Q9QXD1\|ACOX2_MOUSE	269	882	614	n/a	65.93	681	40.98	20.49	5e-83	Peroxisomal acyl-coenzyme A oxidase 2 OS Mus musculus GN Acox2 PE 1 SV 1
blastp_pdb	2ddh_A	328	882	555	n/a	63.39	661	47.97	16.95	1e-102	mol:protein length:661 Acyl-CoA oxidase
	1is2_B	328	882	555	n/a	63.39	661	47.97	16.95	1e-102	mol:protein length:661 acyl-CoA oxidase
	1is2_A	328	882	555	n/a	63.39	661	47.97	16.95	1e-102	mol:protein length:661 acyl-CoA oxidase
	1w07_B	327	901	575	n/a	63.43	659	47.13	18.42	3e-99	mol:protein length:659 ACYL-COA OXIDASE
	1w07_A	327	901	575	n/a	63.43	659	47.13	18.42	3e-99	mol:protein length:659 ACYL-COA OXIDASE
	2fon_C	327	885	559	n/a	56.66	683	49.35	18.60	2e-97	mol:protein length:683 peroxisomal acyl-CoA oxidase 1A
	2fon_B	327	885	559	n/a	56.66	683	49.35	18.60	2e-97	mol:protein length:683 peroxisomal acyl-CoA oxidase 1A
	2fon_A	327	885	559	n/a	56.66	683	49.35	18.60	2e-97	mol:protein length:683 peroxisomal acyl-CoA oxidase 1A
rpsblast_cdd	gnl\|CDD\|73248	242	885	644	Gaps:76	99.34	610	37.13	18.81	1e-139	cd01150 AXO Peroxisomal acyl-CoA oxidases (AXO) catalyze the first set in the peroxisomal fatty acid beta-oxidation the alpha beta dehydrogenation of the corresponding trans-enoyl-CoA by FAD which becomes reduced. In a second oxidative half-reaction the reduced FAD is reoxidized by molecular oxygen. AXO is generally a homodimer but it has been reported to form a different type of oligomer in yeast. There are several subtypes of AXO's based on substrate specificity. Palmitoyl-CoA oxidase acts on straight-chain fatty acids and prostanoids whereas the closely related Trihydroxycoprostanoly-CoA oxidase has the greatest activity for 2-methyl branched side chains of bile precursors. Pristanoyl-CoA oxidase acts on 2-methyl branched fatty acids. AXO has an additional domain C-terminal to the region with similarity to acyl-CoA dehydrogenases which is included in this alignment..
	gnl\|CDD\|110733	731	899	169	Gaps:14	90.86	186	36.09	19.53	3e-32	pfam01756 ACOX Acyl-CoA oxidase. This is a family of Acyl-CoA oxidases EC:1.3.3.6. Acyl-coA oxidase converts acyl-CoA into trans-2- enoyl-CoA.
	gnl\|CDD\|58331	297	688	392	Gaps:70	99.69	327	25.46	14.42	1e-28	cd00567 ACAD Acyl-CoA dehydrogenase (ACAD). Both mitochondrial acyl-CoA dehydrogenases (ACAD) and peroxisomal acyl-CoA oxidases (AXO) catalyze the alpha beta dehydrogenation of the corresponding trans-enoyl-CoA by FAD which becomes reduced. The reduced form of ACAD is reoxidized in the oxidative half-reaction by electron-transferring flavoprotein (ETF) from which the electrons are transferred to the mitochondrial respiratory chain coupled with ATP synthesis. In contrast AXO catalyzes a different oxidative half-reaction in which the reduced FAD is reoxidized by molecular oxygen. The ACAD family includes the eukaryotic beta-oxidation enzymes short (SCAD) medium (MCAD) long (LCAD) and very-long (VLCAD) chain acyl-CoA dehydrogenases. These enzymes all share high sequence similarity but differ in their substrate specificities. The ACAD family also includes amino acid catabolism enzymes such as Isovaleryl-CoA dehydrogenase (IVD) short/branched chain acyl-CoA dehydrogenases(SBCAD) Isobutyryl-CoA dehydrogenase (IBDH) glutaryl-CoA deydrogenase (GCD) and Crotonobetainyl-CoA dehydrogenase. The mitochondrial ACAD's are generally homotetramers except for VLCAD which is a homodimer. Related enzymes include the SOS adaptive reponse proten aidB Naphthocyclinone hydroxylase (NcnH) and and Dibenzothiophene (DBT) desulfurization enzyme C (DszC).
	gnl\|CDD\|32143	348	696	349	Gaps:68	72.52	393	29.47	14.39	4e-20	COG1960 CaiA Acyl-CoA dehydrogenases [Lipid metabolism].
	gnl\|CDD\|29658	336	692	357	Gaps:67	77.75	373	28.97	17.59	9e-13	cd01158 SCAD/SBCAD Short chain acyl-CoA dehydrogenase (SCAD). SCAD is a mitochondrial beta-oxidation enzyme. It catalyzes the alpha beta dehydrogenation of the corresponding trans-enoyl-CoA by FAD which becomes reduced. The reduced form of SCAD is reoxidized in the oxidative half-reaction by electron-transferring flavoprotein (ETF) from which the electrons are transferred to the mitochondrial respiratory chain coupled with ATP synthesis. This subgroup also contains the eukaryotic short/branched chain acyl-CoA dehydrogenase(SBCAD) the bacterial butyryl-CoA dehydorgenase(BCAD) and 2-methylbutyryl-CoA dehydrogenase which is involved in isoleucine catabolism. These enzymes are homotetramers..
rpsblast_kog	gnl\|CDD\|35358	242	902	661	Gaps:46	96.27	670	39.38	18.45	1e-160	KOG0136 KOG0136 KOG0136 Acyl-CoA oxidase [Lipid transport and metabolism].
	gnl\|CDD\|35357	245	879	635	Gaps:64	95.16	661	31.80	17.17	9e-96	KOG0135 KOG0135 KOG0135 Pristanoyl-CoA/acyl-CoA oxidase [Lipid transport and metabolism Secondary metabolites biosynthesis transport and catabolism].
	gnl\|CDD\|35360	335	544	210	Gaps:33	41.90	432	31.49	18.78	6e-14	KOG0138 KOG0138 KOG0138 Glutaryl-CoA dehydrogenase [Amino acid transport and metabolism].
	gnl\|CDD\|35362	348	544	197	Gaps:26	42.40	408	30.06	12.72	2e-11	KOG0140 KOG0140 KOG0140 Medium-chain acyl-CoA dehydrogenase [Lipid transport and metabolism].
	gnl\|CDD\|35361	334	677	344	Gaps:68	69.35	398	27.54	14.86	5e-10	KOG0139 KOG0139 KOG0139 Short-chain acyl-CoA dehydrogenase [Lipid transport and metabolism].

Other analysis

Functional Gbrowse

Structural Gbrowse

Genome Mapping at gene locus

Analysis	Hit name	RefStart	RefEnd	Hit length	Hit identity	Hit coverage	eValue	Hit description
blastx_uniprot_trembl	Q0USK5	564012	565162	392	82.77	97.70	n/a	Putative uncharacterized protein - Phaeosphaeria nodorum (Septoria nodorum)
	A6S6F4	563614	565730	698	68.41	98.85	n/a	Putative uncharacterized protein - Botryotinia fuckeliana (strain B05.10) (Noble rot fungus) (Botrytis cinerea)
	Q1DRG6	563602	565733	693	67.24	100.00	n/a	Putative uncharacterized protein - Coccidioides immitis
	Q2USC8	563614	565733	694	65.60	99.28	n/a	Acyl-CoA oxidase - Aspergillus oryzae
	A1DCV0	563614	565733	692	65.50	99.28	n/a	Acyl-CoA oxidase - Neosartorya fischeri (strain ATCC 1020 / DSM 3700 / NRRL 181) (Aspergillus fischerianus (strain ATCC 1020 / DSM 3700 / NRRL 181))
	A7EY23	563614	565730	735	68.41	93.88	n/a	Putative uncharacterized protein - Sclerotinia sclerotiorum (strain ATCC 18683 / 1980 / Ss-1) (White mold) (Whetzelinia sclerotiorum)
	Q0CJ26	563605	565733	693	63.97	99.71	n/a	Putative uncharacterized protein - Aspergillus terreus (strain NIH 2624)
	A1CDU2	563614	565733	692	64.05	99.28	n/a	Acyl-CoA oxidase - Aspergillus clavatus
	Q5AY78	563602	565733	696	62.93	100.00	n/a	Putative uncharacterized protein - Emericella nidulans (Aspergillus nidulans)
	Q4WGS8	564393	565733	444	65.32	100.00	n/a	Fatty-acyl coenzyme A oxidase - Aspergillus fumigatus (Sartorya fumigata)
blastx_FNG31_prot	SNU05259.1	564012	565733	663	84.21	85.97	n/a	Stagonospora nodorum hypothetical protein translation
	BC1G_08482.1	563614	565730	698	68.41	98.85	n/a	Botrytis cinerea hypothetical protein translation 699 aa
	CIMG_07097.2	563602	565733	693	67.24	100.00	n/a	Coccidioides immitis hypothetical protein translation 694 aa
	AO090005000479	563614	565733	694	65.60	99.28	n/a	Aspergillus oryzae acyl-CoA oxidase
	FG02287.1	563605	565715	696	65.50	98.71	n/a	fusarium_graminearum hypothetical protein 697 aa
	SS1G_10238.1	563614	565730	735	68.41	93.88	n/a	sclerotinia_sclerotiorum hypothetical protein translation 736 aa
	AN6752	563602	565733	696	62.93	100.00	n/a	Aspergillus nidulans AN6752.3 conserved hypothetical protein translation 697 aa
	gi:70986827:ref:XP_748901.1:	564393	565733	444	65.32	100.00	n/a	Aspergillus fumigatus Af293 palmitoyl-CoA oxidase 1
	UM02208.1	563605	565667	688	48.56	95.78	n/a	ustilago_maydis hypothetical protein 689 aa
	RO3G_07773.1	563626	565694	704	47.63	95.74	n/a	rhizopus_oryzae hypothetical protein translation 705 aa
blat_BES	QS0AAE138ZB06RM1	562810	563492	788	n/a	n/a	n/a	n/a
	QS0AAD9ZH12RM1	565568	566259	814	n/a	n/a	n/a	n/a
	QS0AAD60ZC11FM2	541345	573784	753	n/a	n/a	n/a	n/a
	QS0AAD61ZC04RM1	541480	574136	1080	n/a	n/a	n/a	n/a
	QS0AAE152ZH03FM1	545137	577494	804	n/a	n/a	n/a	n/a
	QS0AAE159ZD05RM1	542151	574541	841	n/a	n/a	n/a	n/a
	QS0AAE136ZF09FM1	541676	574143	749	n/a	n/a	n/a	n/a
	QS0AAE141ZE08FM1	543639	575946	769	n/a	n/a	n/a	n/a
	QS0AAE149ZB09RM1	541703	574144	747	n/a	n/a	n/a	n/a
blastx_SN15proteins	gnl:WGS:AAGI:SNOT_05259.2:gb:EAT87650	564012	565162	392	82.77	97.70	n/a	n/a
blastx_SN15proteins	gnl:WGS:AAGI:SNOT_05063.2:gb:EAT87454	564393	565685	438	43.99	94.98	n/a	n/a
RepeatMasker_SR	(TGG)n	563336	563389	180	n/a	n/a	n/a	n/a
RepeatMasker_LC	no results
sim4_Lm_allest	RS0AAB7YG05FM1	563063	563330	268	100.00	100.00	n/a	Lm isolate M1 - mycelia grown for 5 days and 8 hours on oilseed rape juice medium
sim4_lm_allest6_clctg	RS0AAB7YG05FM1	563063	563330	268	100.00	100.00	n/a	Lm isolate M1 - mycelia grown for 5 days and 8 hours on oilseed rape juice medium
sim4_cDNA_BHowlett	no results
blastx_uniprot_sprot	Q9ZQP2	563668	565733	664	37.37	98.34	n/a	Putative acyl-coenzyme A oxidase 1.2 peroxisomal - Arabidopsis thaliana (Mouse-ear cress)
	O65202	564021	565733	664	41.08	83.58	n/a	Acyl-coenzyme A oxidase 1 peroxisomal - Arabidopsis thaliana (Mouse-ear cress)
	P07872	564018	565679	661	41.71	81.24	n/a	Acyl-coenzyme A oxidase 1 peroxisomal - Rattus norvegicus (Rat)
	Q9R0H0	564018	565679	661	41.15	81.24	n/a	Acyl-coenzyme A oxidase 1 peroxisomal - Mus musculus (Mouse)
	Q5RC19	564018	565679	660	41.53	81.36	n/a	Acyl-coenzyme A oxidase 1 peroxisomal - Pongo pygmaeus (Orangutan)
	Q15067	564018	565679	660	41.53	81.36	n/a	Acyl-coenzyme A oxidase 1 peroxisomal - Homo sapiens (Human)
	Q9Z1N0	564018	565679	661	40.97	81.24	n/a	Acyl-coenzyme A oxidase 1 peroxisomal - Cavia porcellus (Guinea pig)
	Q3SZP5	564018	565679	660	40.60	81.36	n/a	Acyl-coenzyme A oxidase 1 peroxisomal - Bos taurus (Bovine)
	Q8HYL8	564018	565667	661	40.34	80.64	n/a	Acyl-coenzyme A oxidase 1 peroxisomal - Phascolarctos cinereus (Koala)
	Q9QXD1	564033	565667	681	36.98	77.83	n/a	Acyl-coenzyme A oxidase 2 peroxisomal - Mus musculus (Mouse)
REPET	no results
MUMer_show_coords_lm_WA74	no results