GRS - Genome Report System

Leptosphaeria maculans GRS

Functional annotation

Lema_P034190.1

Located on : lm_SuperContig_3_v2

Analysis	Type	ID	RefStart	RefEnd
egn4_orf	gene	Lema_G034190.1	792723	800000
	mRNA	Lema_T034190.1	792723	800000
	polypeptide	Lema_P034190.1	792723	800000

>Lema_P034190.1 | 2012 aa 
MGQGFSLTTLSAGSANIDVPELADLQYEKSLGAARFMKAVRARHKHGLVVARVVMKPYAQFNFQTHVKKLLNERKLLAQVPNALAYHRVIETAACGYLVRQYIHSSLYDRLSTRPFLEDIEKKWLSFQLLCAVRDCHARNIHHGDIKTENVLVTSWNWLYLTDFSSSYKPAHLPEDNPADFSFYFDLSGRRTCYLAPERFLAAGQQPEGEGNVNWAMDIFSVGCVIAELFLEAPIFSLSQLFKYRQGEYNPEHSHLNKIQDSNIRELIMHMIQVDPNSRMSAEDYLTHWRDKVFPGYFYGFLQQYMHSITDPSFGQKPGTTVAEHLGEPDERIDQIYNDYDKIAHLLSENSGQELAKSQHSPPKPNARLFPLVVNIPNYQHQASPTPSLAFDDGNLIFLTIVVSCLRGTARASARVRGLELLMAFSERLTDEAKLDRVVPYVAQLLTDKSEQVKIAALRTLTQILAMVQVVSPINAYIFPEYVLPRLEAYLPDPSASVSPLVRMQYAFCIGTLATTAARYLDMIQALRAEGSLPATDPETEDDMSSSTHRNQFDSDRRILLEAFEKHTKSLLTDPDTSVRRAMLKSVSDLCVFFGSPRANDVVLSHLNTYLNDPDWMLKCGFFEAIVGVAVFVGGASLEGYILPLMVQALTDPEEFVVEKVVRALSSMAELGLFQRSKTWELVDIVARLTMHPNLWIREAAAEFISSANRYLSIADTHSILVNLIRPYLKVVPSDFSELALLESLKPPFSRLFLEMTSNWAMQAQKGSFWASAKQQQTISFGSSSDSLPTISGRDLDPKILQRLAKNEEDDLWIKKLRNAGMTHEDDFKLVALREFIWRTTNRRRSDSLATPPTKFNSIIALKDLGIKALTVLFDEDVRQAVEQTTKLESQQQGYVQPRTIRDALLDASTTEAEALADRVPHAESQAGRLIREETGTRRLSIPSPSSESTLPEGETGSHSLHVPKGPDSPSGSFGADDHTFSLRHRHSALGLLGKGESKASAEIGTTSANAFGKVDGIHARETSRARQPTSPLVSDTPNNPSRIRFRNAHNYTGNDPAILKLLDSMLSERFPSNEIEIGPRIQPPMQRQPIRTKDSHLASTGVPWRPEGTLVASFGEHTAAVTRILVSPDHAFFISGSDDGSVKIWDTSRLERNITRRSRQTYRLGESVKVTSLVFVENTYSFVATGSDGSVHVVRVDFYRGQDGAAKFGRPRLLREYQLQKGDHALWSDHHNEDNKSVLLMATNTSKVIALDLKTMEELYTLQNPLNHGTPTCFCVDRRAHWLLLGTSHGALDLWDLRFKLRLKAWVCHGASPIHRLYQVFQPKSKKTRLYIAGGNSQGEITVWDWEKQICKEVYRTGTCKDIGTKSTTLIDLDEEKPGGMLSRFATSLEPTANSTNDRGISALAVHTQAVDDRTDSKPHTFLLTAGPDWKVRYWDTNRADGSMVVSGLEADEAKPQYTASQPSPETIVVTERLSQPQASAINGRDSRSSSTSKKPSQKSSKSGLISLQQQHLLKSHMDNILDVALIEQPYGIVISADRQIHWDCLLLSRIYRHPIHLSDMPYCMRCRASFRGPGRYCGRHGINEGRDRRYPYNAYEHFNYNSDSTDPAGGHMRSRQRDPPSRMRFADEHGGQDMYESNDNYASRGDHNLGGRHDRRTGVIRYGHGDFNVDTSLHQPLVYTFNTLSRAHAIRSMTYNVSPLGDRSVTAEANMEREMCHICKHWFPDHERLEYHQQEFSAGCEEHRKCPPCHHIPLTRPELRLQRATMRLTTDLINGSISFINCLTERELDLRGHKIAAIENMGAARDNDAIDLTDNDIAQLGNFPLQPRLRTLFLAQNRISNIQPNLSSSIPNLRTLVLTKNRIAELADLDPLAGFKNLIYLSLIGNPVTSKEYYRYWVIWRCPSVRYLDFAKVFDVERKKAKELFGTADEPTELASKIMGIKSKGFVVPTLIDGSESSNKERIYTEEEKKRMRAAILNAKSLAEMAKLEKEFAEGRIPAHILEGGDPMET

DbXrefs

Domain/Motif (Interproscan results)

Localization / Targeting

Predicted function

Blast based analysis

Analysis	Hit	start	end	length	Note	Hit coverage	Hit length	Hit pident	Hit pcons	eValue	Hit description
blastp_kegg	ssl:SS1G_08574	1	1505	1505	n/a	85.38	1566	58.19	17.50	0.0	hypothetical protein K08333 phosphoinositide-3-kinase regulatory subunit 4 p150 [EC:2.7.11.1]
	fgr:FG05306.1	1	1540	1540	n/a	88.72	1525	54.47	20.03	0.0	hypothetical protein K08333 phosphoinositide-3-kinase regulatory subunit 4 p150 [EC:2.7.11.1]
	mgr:MGG_06100	1	1540	1540	n/a	84.78	1551	55.13	18.02	0.0	hypothetical protein
	ncr:NCU06626	1	1437	1437	n/a	80.20	1510	54.25	19.82	0.0	hypothetical protein
	ang:An08g07540	1	1540	1540	n/a	80.50	1595	55.37	19.70	0.0	hypothetical protein K08333 phosphoinositide-3-kinase regulatory subunit 4 p150 [EC:2.7.11.1]
	ani:AN0576.2	1	1540	1540	n/a	82.61	1599	56.62	18.62	0.0	hypothetical protein K08333 phosphoinositide-3-kinase regulatory subunit 4 p150 [EC:2.7.11.1]
	nfi:NFIA_056890	1	1540	1540	n/a	81.98	1620	57.00	18.45	0.0	protein kinase (VPS15) putative K08333 phosphoinositide-3-kinase regulatory subunit 4 p150 [EC:2.7.11.1]
	aor:AO090023000496	1	1540	1540	n/a	84.00	1612	55.24	19.20	0.0	protein kinase containing WD40 repeats K08333 phosphoinositide-3-kinase regulatory subunit 4 p150 [EC:2.7.11.1]
	afm:AFUA_6G11190	1	1540	1540	n/a	78.31	1637	56.79	18.88	0.0	protein kinase (VPS15) (EC:2.7.1.-) K08333 phosphoinositide-3-kinase regulatory subunit 4 p150 [EC:2.7.11.1]
	bfu:BC1G_07434	1	548	548	n/a	88.09	613	63.15	16.85	0.0	hypothetical protein K08333 phosphoinositide-3-kinase regulatory subunit 4 p150 [EC:2.7.11.1]
blastp_uniprot_sprot	sp\|Q9UVG6\|VPS15_PICPA	16	1307	1292	n/a	66.94	1340	41.69	21.18	0.0	Putative serine/threonine-protein kinase VPS15 OS Pichia pastoris GN VPS15 PE 3 SV 3
	sp\|P22219\|VPS15_YEAST	22	1356	1335	n/a	56.46	1454	39.83	24.00	1e-163	Serine/threonine-protein kinase VPS15 OS Saccharomyces cerevisiae GN VPS15 PE 1 SV 3
	sp\|Q99570\|PI3R4_HUMAN	21	1459	1439	n/a	56.26	1358	44.90	20.29	1e-158	Phosphoinositide 3-kinase regulatory subunit 4 OS Homo sapiens GN PIK3R4 PE 1 SV 3
	sp\|Q8VD65\|PI3R4_MOUSE	21	1449	1429	n/a	55.38	1358	45.35	20.21	1e-158	Phosphoinositide 3-kinase regulatory subunit 4 OS Mus musculus GN Pik3r4 PE 1 SV 3
	sp\|P0C0R5\|PI3R4_RAT	21	1449	1429	n/a	55.38	1358	45.21	20.61	1e-157	Phosphoinositide 3-kinase regulatory subunit 4 OS Rattus norvegicus GN Pik3r4 PE 3 SV 2
	sp\|O42900\|PPK19_SCHPO	79	1539	1461	n/a	42.97	1706	43.79	19.51	1e-154	Serine/threonine-protein kinase ppk19 OS Schizosaccharomyces pombe GN ppk19 PE 1 SV 1
	sp\|Q5R9I3\|PI3R4_PONAB	21	1459	1439	n/a	56.26	1358	44.37	20.42	1e-154	Phosphoinositide 3-kinase regulatory subunit 4 OS Pongo abelii GN PIK3R4 PE 2 SV 3
	sp\|Q54S77\|VPS15_DICDI	21	1448	1428	n/a	34.38	1966	47.04	18.64	1e-152	Probable serine/threonine-protein kinase vps15 OS Dictyostelium discoideum GN vps15 PE 3 SV 1
	sp\|Q4WV66\|RU2A_ASPFU	1768	2011	244	n/a	90.91	253	64.35	13.04	2e-89	U2 small nuclear ribonucleoprotein A' OS Aspergillus fumigatus GN lea1 PE 3 SV 1
	sp\|Q7S9P4\|RU2A_NEUCR	1768	2008	241	n/a	89.29	252	61.78	12.00	3e-81	U2 small nuclear ribonucleoprotein A' OS Neurospora crassa GN lea-1 PE 3 SV 1
blastp_pdb	1a9n_C	1768	1927	160	n/a	90.34	176	49.69	20.75	1e-41	mol:protein length:176 U2A
	1a9n_A	1768	1927	160	n/a	90.34	176	49.69	20.75	1e-41	mol:protein length:176 U2A
	3gre_A	1133	1356	224	n/a	37.99	437	31.33	25.90	6e-18	mol:protein length:437 Serine/threonine-protein kinase VPS15
rpsblast_cdd	gnl\|CDD\|29142	24	288	265	Gaps:28	98.83	256	28.85	17.79	6e-29	cd00180 S_TKc Serine/Threonine protein kinases catalytic domain. Phosphotransferases of the serine or threonine-specific kinase subfamily. The enzymatic activity of these protein kinases is controlled by phosphorylation of specific residues in the activation segment of the catalytic domain sometimes combined with reversible conformational changes in the C-terminal autoregulatory tail..
	gnl\|CDD\|128516	41	288	248	Gaps:31	96.31	244	30.21	17.45	3e-26	smart00220 S_TKc Serine/Threonine protein kinases catalytic domain. Phosphotransferases. Serine or threonine-specific kinase subfamily.
	gnl\|CDD\|109137	25	288	264	Gaps:29	98.85	260	26.85	17.51	2e-17	pfam00069 Pkinase Protein kinase domain.
	gnl\|CDD\|30861	24	412	389	Gaps:45	100.00	384	17.71	16.93	2e-16	COG0515 SPS1 Serine/threonine protein kinase [General function prediction only / Signal transduction mechanisms / Transcription / DNA replication recombination and repair].
	gnl\|CDD\|88482	24	285	262	Gaps:21	96.42	279	20.07	21.56	7e-16	cd05581 STKc_PDK1 STKc_PDK1: Serine/Threonine Kinases (STKs) Phosphoinositide-dependent kinase 1 (PDK1) subfamily catalytic (c) domain. STKs catalyze the transfer of the gamma-phosphoryl group from ATP to serine/threonine residues on protein substrates. The PDK1 subfamily is part of a larger superfamily that includes the catalytic domains of other protein STKs protein tyrosine kinases RIO kinases aminoglycoside phosphotransferase choline kinase and phosphoinositide 3-kinase (PI3K). PDK1 carries an N-terminal catalytic domain and a C-terminal pleckstrin homology (PH) domain that binds phosphoinositides. It phosphorylates the activation loop of AGC kinases that are regulated by PI3K such as PKB SGK and PKC among others and is crucial for their activation. Thus it contributes in regulating many processes including metabolism growth proliferation and survival. PDK1 also has the ability to autophosphorylate and is constitutively active in mammalian cells. PDK1 is essential for normal embryo development and is important in regulating cell volume..
rpsblast_kog	gnl\|CDD\|36454	1	1540	1540	Gaps:211	99.44	1431	34.36	17.22	0.0	KOG1240 KOG1240 KOG1240 Protein kinase containing WD40 repeats [Signal transduction mechanisms].
	gnl\|CDD\|36857	1768	2001	234	Gaps:4	99.57	233	46.12	18.10	3e-54	KOG1644 KOG1644 KOG1644 U2-associated snRNP A' protein [RNA processing and modification].
	gnl\|CDD\|35814	97	288	192	Gaps:60	65.02	323	27.62	16.67	4e-18	KOG0594 KOG0594 KOG0594 Protein kinase PCTAIRE and related kinases [General function prediction only].
	gnl\|CDD\|35835	25	288	264	Gaps:34	52.21	475	29.44	16.94	2e-16	KOG0615 KOG0615 KOG0615 Serine/threonine protein kinase Chk2 and related proteins [Cell cycle control cell division chromosome partitioning].
	gnl\|CDD\|35803	29	288	260	Gaps:35	68.38	370	26.48	19.76	1e-15	KOG0583 KOG0583 KOG0583 Serine/threonine protein kinase [Signal transduction mechanisms].

Other analysis

Functional Gbrowse

Structural Gbrowse

Genome Mapping at gene locus

Analysis	Hit name	RefStart	RefEnd	Hit length	Hit identity	Hit coverage	eValue	Hit description
blastx_uniprot_trembl	Q0U2E3	792723	799997	1598	82.03	96.12	n/a	Putative uncharacterized protein - Phaeosphaeria nodorum (Septoria nodorum)
	A7ETB9	792723	797460	1566	53.80	99.94	n/a	Putative uncharacterized protein - Sclerotinia sclerotiorum (strain ATCC 18683 / 1980 / Ss-1) (White mold) (Whetzelinia sclerotiorum)
	A7KAP0	792723	797460	1602	50.47	99.94	n/a	Vps15p - Penicillium chrysogenum (Penicillium notatum)
	A1CU03	792723	797460	1610	50.03	99.94	n/a	Protein kinase - Aspergillus clavatus
	A1DNG9	792723	797457	1620	50.09	99.57	n/a	Protein kinase - Neosartorya fischeri (strain ATCC 1020 / DSM 3700 / NRRL 181) (Aspergillus fischerianus (strain ATCC 1020 / DSM 3700 / NRRL 181))
	Q2UHC8	792723	797460	1612	49.47	99.94	n/a	Protein kinase containing WD40 repeats - Aspergillus oryzae
	Q5BFV4	792723	797460	1599	49.06	99.94	n/a	Putative uncharacterized protein - Emericella nidulans (Aspergillus nidulans)
	Q0CMN6	792723	797460	1619	48.98	99.75	n/a	Putative uncharacterized protein - Aspergillus terreus (strain NIH 2624)
	A4QW52	792723	797460	1551	48.84	99.94	n/a	Putative uncharacterized protein - Magnaporthe grisea (Rice blast fungus) (Pyricularia grisea)
	Q8NJL6	792723	797460	1637	49.41	98.78	n/a	Possible kinase with calcium binding domain - Aspergillus fumigatus (Sartorya fumigata)
	Q0U2E3	792723	799997	1598	82.03	96.12	n/a	Putative uncharacterized protein - Phaeosphaeria nodorum (Septoria nodorum)
	A7ETB9	792723	797460	1566	53.80	99.94	n/a	Putative uncharacterized protein - Sclerotinia sclerotiorum (strain ATCC 18683 / 1980 / Ss-1) (White mold) (Whetzelinia sclerotiorum)
	A7KAP0	792723	797460	1602	50.47	99.94	n/a	Vps15p - Penicillium chrysogenum (Penicillium notatum)
	A1CU03	792723	797460	1610	50.03	99.94	n/a	Protein kinase - Aspergillus clavatus
	A1DNG9	792723	797457	1620	50.09	99.57	n/a	Protein kinase - Neosartorya fischeri (strain ATCC 1020 / DSM 3700 / NRRL 181) (Aspergillus fischerianus (strain ATCC 1020 / DSM 3700 / NRRL 181))
	Q2UHC8	792723	797460	1612	49.47	99.94	n/a	Protein kinase containing WD40 repeats - Aspergillus oryzae
	Q5BFV4	792723	797460	1599	49.06	99.94	n/a	Putative uncharacterized protein - Emericella nidulans (Aspergillus nidulans)
	Q0CMN6	792723	797460	1619	48.98	99.75	n/a	Putative uncharacterized protein - Aspergillus terreus (strain NIH 2624)
	A4QW52	792723	797460	1551	48.84	99.94	n/a	Putative uncharacterized protein - Magnaporthe grisea (Rice blast fungus) (Pyricularia grisea)
	Q8NJL6	792723	797460	1637	49.41	98.78	n/a	Possible kinase with calcium binding domain - Aspergillus fumigatus (Sartorya fumigata)
blastx_FNG31_prot	SNU14089.1	792723	797463	1563	80.10	100.00	n/a	Stagonospora nodorum hypothetical protein translation
	SS1G_08574.1	792723	797460	1566	53.80	99.94	n/a	sclerotinia_sclerotiorum hypothetical protein translation 1567 aa
	FG05306.1	792723	797460	1525	50.07	99.93	n/a	fusarium_graminearum hypothetical protein 1526 aa
	jgi:Triree:43124	792723	797460	1530	49.77	99.93	n/a	Trichoderma reesei
	AO090023000496	792723	797460	1612	49.47	99.94	n/a	Aspergillus oryzae protein kinase containing WD40 repeats
	AN0576	792723	797460	1599	49.06	99.94	n/a	Aspergillus nidulans AN0576.3 conserved hypothetical protein translation 1600 aa
	MGG_06100.5	792723	797460	1551	48.84	99.94	n/a	magnaporthe_grisea hypothetical protein translation 1552 aa
	gi:70992309:ref:XP_751003.1:	792723	797460	1637	49.41	98.78	n/a	Aspergillus fumigatus Af293 protein kinase VPS15
	CHG04491.1	792723	797460	1483	48.77	98.45	n/a	Chaetomium globosum hypothetical protein translation 1484 aa
	CIMG_00240.2	792723	797460	1624	47.87	99.94	n/a	Coccidioides immitis hypothetical protein translation 1625 aa
	SNU14090.1	798918	799997	245	86.89	99.59	n/a	Stagonospora nodorum hypothetical protein translation
	SS1G_08575.1	799165	799994	267	59.43	79.40	n/a	sclerotinia_sclerotiorum hypothetical protein translation 268 aa
	AO090026000751	799159	799985	251	58.05	81.67	n/a	Aspergillus oryzae U2-associated snRNP A protein
	CIMG_00680.2	799168	799422	240	63.53	35.42	n/a	Coccidioides immitis hypothetical protein translation 241 aa
	MGG_13209.5	799168	799422	243	64.71	34.98	n/a	magnaporthe_grisea hypothetical protein translation 244 aa
	CHG04490.1	799165	799973	247	57.29	80.57	n/a	Chaetomium globosum hypothetical protein translation 248 aa
	BC1G_07432.1	799561	799994	130	49.61	99.23	n/a	Botrytis cinerea hypothetical protein translation 131 aa
	FG05305.1	799165	799422	243	61.63	35.39	n/a	fusarium_graminearum hypothetical protein 244 aa
	jgi:Triree:22170	799165	799422	243	60.47	35.39	n/a	Trichoderma reesei
	SNU14089.1	792723	797463	1563	80.10	100.00	n/a	Stagonospora nodorum hypothetical protein translation
	SS1G_08574.1	792723	797460	1566	53.80	99.94	n/a	sclerotinia_sclerotiorum hypothetical protein translation 1567 aa
	FG05306.1	792723	797460	1525	50.07	99.93	n/a	fusarium_graminearum hypothetical protein 1526 aa
	jgi:Triree:43124	792723	797460	1530	49.77	99.93	n/a	Trichoderma reesei
	AO090023000496	792723	797460	1612	49.47	99.94	n/a	Aspergillus oryzae protein kinase containing WD40 repeats
	AN0576	792723	797460	1599	49.06	99.94	n/a	Aspergillus nidulans AN0576.3 conserved hypothetical protein translation 1600 aa
	MGG_06100.5	792723	797460	1551	48.84	99.94	n/a	magnaporthe_grisea hypothetical protein translation 1552 aa
	gi:70992309:ref:XP_751003.1:	792723	797460	1637	49.41	98.78	n/a	Aspergillus fumigatus Af293 protein kinase VPS15
	CHG04491.1	792723	797460	1483	48.77	98.45	n/a	Chaetomium globosum hypothetical protein translation 1484 aa
	CIMG_00240.2	792723	797460	1624	47.87	99.94	n/a	Coccidioides immitis hypothetical protein translation 1625 aa
	gi:70997613:ref:XP_753548.1:	799159	800012	253	58.69	84.19	n/a	Aspergillus fumigatus Af293 small nuclear ribonucleoprotein U2 A
blat_BES	QS0AAD29ZG12FM1	797886	798479	819	n/a	n/a	n/a	n/a
	QS0AAD7ZF01FM2	798115	798795	764	n/a	n/a	n/a	n/a
	QS0AAD14ZC02FM1	794841	795270	783	n/a	n/a	n/a	n/a
	QS0AAD19ZG04FM1	797521	797893	836	n/a	n/a	n/a	n/a
	QS0AAD55ZB01RM1	797887	798818	1091	n/a	n/a	n/a	n/a
	QS0AAD56ZE06RM1	797887	798734	1124	n/a	n/a	n/a	n/a
	QS0AAE112ZD02FM1	796698	797599	1067	n/a	n/a	n/a	n/a
	QS0AAE143ZC12RM1	799353	800016	739	n/a	n/a	n/a	n/a
	QS0AAE151ZD09RM1	799983	800662	757	n/a	n/a	n/a	n/a
blastx_SN15proteins	gnl:WGS:AAGI:SNOT_14090.2:gb:EAT78715	792723	799997	1598	82.03	96.12	n/a	n/a
blastx_SN15proteins	gnl:WGS:AAGI:SNOT_14090.2:gb:EAT78715	792723	799997	1598	82.03	96.12	n/a	n/a
RepeatMasker_SR	no results
RepeatMasker_LC	no results
sim4_Lm_allest	no results
sim4_lm_allest6_clctg	no results
sim4_cDNA_BHowlett	no results
blastx_uniprot_sprot	Q9UVG6	792723	797460	1340	37.23	96.42	n/a	Putative serine/threonine-protein kinase VPS15 - Pichia pastoris (Yeast)
	O42900	792971	795183	1706	39.15	44.02	n/a	Serine/threonine-protein kinase ppk19 - Schizosaccharomyces pombe (Fission yeast)
	Q99570	792783	796863	1358	39.11	81.52	n/a	Phosphoinositide 3-kinase regulatory subunit 4 - Homo sapiens (Human)
	Q5R9I3	792783	796863	1358	39.02	80.78	n/a	Phosphoinositide 3-kinase regulatory subunit 4 - Pongo pygmaeus (Orangutan)
	Q8VD65	792783	796863	1358	39.11	80.78	n/a	Phosphoinositide 3-kinase regulatory subunit 4 - Mus musculus (Mouse)
	P0C0R5	792783	796863	1358	39.11	80.78	n/a	Phosphoinositide 3-kinase regulatory subunit 4 - Rattus norvegicus (Rat)
	P22219	793114	796887	1454	33.95	70.70	n/a	Serine/threonine-protein kinase VPS15 - Saccharomyces cerevisiae (Baker's yeast)
	Q5BGW9	799174	799994	230	56.04	90.00	n/a	U2 small nuclear ribonucleoprotein A' - Emericella nidulans (Aspergillus nidulans)
	Q9UVG6	792723	797460	1340	37.23	96.42	n/a	Putative serine/threonine-protein kinase VPS15 - Pichia pastoris (Yeast)
	Q4WV66	799159	800012	253	58.69	84.19	n/a	U2 small nuclear ribonucleoprotein A' - Aspergillus fumigatus (Sartorya fumigata)
REPET	no results
MUMer_show_coords_lm_WA74	no results