GRS - Genome Report System

Leptosphaeria maculans GRS

Functional annotation

Lema_P025910.1

Gene Identifier

DbXrefs

Domain/Motif (Interproscan results)

Localization / Targeting

Predicted function

Blast based analysis

Analysis	Hit	start	end	length	Note	Hit coverage	Hit length	Hit pident	Hit pcons	eValue	Hit description
blastp_kegg	ani:AN0272.2	1	358	358	n/a	93.68	364	68.04	12.61	1e-160	hypothetical protein
	nfi:NFIA_021750	1	359	359	n/a	93.96	364	66.08	13.16	1e-157	Phosphotransferase enzyme family domain protein
	afm:AFUA_1G02880	1	359	359	n/a	93.96	364	65.79	13.45	1e-156	Phosphotransferase enzyme family domain protein K06979
	aor:AO090005000779	1	358	358	n/a	93.68	364	63.93	14.96	1e-153	predicted aminoglycoside phosphotransferase
	bfu:BC1G_06343	1	357	357	n/a	90.91	374	64.12	14.41	1e-151	hypothetical protein
	ang:An01g05030	1	366	366	n/a	89.03	392	62.46	14.33	1e-150	hypothetical protein
	ssl:SS1G_03106	1	357	357	n/a	95.92	368	62.04	14.45	1e-150	hypothetical protein
	fgr:FG00356.1	1	369	369	n/a	32.00	1125	60.28	15.28	1e-145	hypothetical protein
	ncr:NCU00513	1	369	369	n/a	93.04	388	58.17	14.68	1e-138	similar to phosphotransferase enzyme family domain protein
	pan:PODANSg4354	1	366	366	n/a	94.21	380	60.34	13.13	1e-137	hypothetical protein
blastp_uniprot_sprot	sp\|Q6JQN1\|ACD10_HUMAN	28	355	328	n/a	24.17	1059	40.23	21.48	6e-54	Acyl-CoA dehydrogenase family member 10 OS Homo sapiens GN ACAD10 PE 2 SV 1
	sp\|Q8K370\|ACD10_MOUSE	28	355	328	n/a	23.57	1069	38.89	24.21	1e-52	Acyl-CoA dehydrogenase family member 10 OS Mus musculus GN Acad10 PE 2 SV 1
	sp\|Q5ZHT1\|ACD11_CHICK	29	356	328	n/a	32.05	777	41.77	20.48	4e-45	Acyl-CoA dehydrogenase family member 11 OS Gallus gallus GN ACAD11 PE 2 SV 1
	sp\|Q5R778\|ACD11_PONAB	12	356	345	n/a	32.52	781	39.37	22.05	3e-43	Acyl-CoA dehydrogenase family member 11 OS Pongo abelii GN ACAD11 PE 2 SV 2
	sp\|Q709F0\|ACD11_HUMAN	12	356	345	n/a	32.56	780	38.58	22.44	8e-42	Acyl-CoA dehydrogenase family member 11 OS Homo sapiens GN ACAD11 PE 1 SV 2
	sp\|B3DMA2\|ACD11_RAT	50	356	307	n/a	31.45	779	38.37	18.37	9e-42	Acyl-CoA dehydrogenase family member 11 OS Rattus norvegicus GN Acad11 PE 1 SV 1
	sp\|Q80XL6\|ACD11_MOUSE	50	356	307	n/a	31.45	779	38.37	16.73	1e-39	Acyl-CoA dehydrogenase family member 11 OS Mus musculus GN Acad11 PE 1 SV 2
blastp_pdb	3dxp_A	6	362	357	n/a	79.39	359	40.35	19.65	1e-61	mol:protein length:359 putative acyl-CoA dehydrogenase
rpsblast_cdd	gnl\|CDD\|88617	29	262	234	Gaps:13	100.00	223	42.60	20.63	7e-64	cd05154 ACAD10_11_like Acyl-CoA dehydrogenase (ACAD) 10 and 11 N-terminal domain and similar proteins. This subfamily is part of a larger superfamily that includes the catalytic domains of other kinases such as the typical serine/threonine/tyrosine protein kinases (PKs) RIO kinases actin-fragmin kinase (AFK) and phosphoinositide 3-kinase (PI3K). This subfamily is composed of bacterial and eukaryotic proteins with similarity to the N-terminal domains of vertebrate ACAD10 and ACAD11. ACADs are a family of flavoproteins that are involved in the beta-oxidation of fatty acyl-CoA derivatives. ACAD deficiency can cause metabolic disorders including muscle fatigue hypoglycemia and hepatic lipidosis among them. There are at least 11 distinct ACADs some of which show distinct substrate specificities to either straight-chain or branched-chain fatty acids. ACAD10 is widely expressed in human tissues and is highly expressed in liver kidney pancreas and spleen. ACAD10 and ACAD11 contain a long N-terminal domain with similarity to phosphotransferases with a PK fold which is absent in other ACADs. They may exhibit multiple functions in acyl-CoA oxidation pathways..
	gnl\|CDD\|32986	6	353	348	Gaps:33	98.13	321	33.02	20.63	5e-45	COG3173 COG3173 Predicted aminoglycoside phosphotransferase [General function prediction only].
	gnl\|CDD\|110623	37	280	244	Gaps:19	96.15	234	26.67	17.33	4e-33	pfam01636 APH Phosphotransferase enzyme family. This family consists of bacterial antibiotic resistance proteins which confer resistance to various aminoglycosides they include:- aminoglycoside 3'-phosphotransferase or kanamycin kinase / neomycin-kanamycin phosphotransferase and streptomycin 3''-kinase or streptomycin 3''-phosphotransferase. The aminoglycoside phosphotransferases inactivate aminoglycoside antibiotics via phosphorylation. This family also includes homoserine kinase. This family is related to fructosamine kinase pfam03881.
	gnl\|CDD\|88612	29	256	228	Gaps:15	96.13	155	28.86	21.48	4e-09	cd05120 APH_ChoK_like Aminoglycoside 3'-phosphotransferase (APH) and Choline Kinase (ChoK) family. The APH/ChoK family is part of a larger superfamily that includes the catalytic domains of other kinases such as the typical serine/threonine/tyrosine protein kinases (PKs) RIO kinases actin-fragmin kinase (AFK) and phosphoinositide 3-kinase (PI3K). The family is composed of APH ChoK ethanolamine kinase (ETNK) macrolide 2'-phosphotransferase (MPH2') an unusual homoserine kinase and uncharacterized proteins with similarity to the N-terminal domain of acyl-CoA dehydrogenase 10 (ACAD10). The members of this family catalyze the transfer of the gamma-phosphoryl group from ATP (or CTP) to small molecule substrates such as aminoglycosides macrolides choline ethanolamine and homoserine. Phosphorylation of the antibiotics aminoglycosides and macrolides leads to their inactivation and to bacterial antibiotic resistance. Phosphorylation of choline ethanolamine and homoserine serves as precursors to the synthesis of important biological compounds such as the major phospholipids phosphatidylcholine and phosphatidylethanolamine and the amino acids threonine methionine and isoleucine..
	gnl\|CDD\|128855	106	256	151	Gaps:21	84.69	196	18.07	15.66	6e-04	smart00587 CHK ZnF_C4 abd HLH domain containing kinases domain. subfamily of choline kinases.
rpsblast_kog	gnl\|CDD\|38674	28	56	29	Gaps:1	28.30	106	46.67	13.33	1.2	KOG3464 KOG3464 KOG3464 60S ribosomal protein L44 [Translation ribosomal structure and biogenesis].
	gnl\|CDD\|37482	97	266	170	Gaps:20	22.71	678	17.53	13.64	1.4	KOG2271 KOG2271 KOG2271 Nuclear pore complex component (sc Nup85) [Nuclear structure Intracellular trafficking secretion and vesicular transport].
	gnl\|CDD\|37479	33	113	81	Gaps:31	20.22	465	22.34	17.02	3.4	KOG2268 KOG2268 KOG2268 Serine/threonine protein kinase [Signal transduction mechanisms General function prediction only].
	gnl\|CDD\|35678	45	80	36	n/a	8.22	438	27.78	16.67	5.0	KOG0457 KOG0457 KOG0457 Histone acetyltransferase complex SAGA/ADA subunit ADA2 [Chromatin structure and dynamics].
	gnl\|CDD\|38721	243	369	127	Gaps:12	21.11	592	21.60	14.40	5.0	KOG3512 KOG3512 KOG3512 Netrin axonal chemotropic factor [Signal transduction mechanisms].

Other analysis

Functional Gbrowse

Structural Gbrowse

Genome Mapping at gene locus

Analysis	Hit name	RefStart	RefEnd	Hit length	Hit identity	Hit coverage	eValue	Hit description
blastx_uniprot_trembl	Q0UUX5	907557	908870	397	83.20	95.97	n/a	Putative uncharacterized protein - Phaeosphaeria nodorum (Septoria nodorum)
	Q2URL6	907557	908861	364	61.16	99.73	n/a	Predicted aminoglycoside phosphotransferase - Aspergillus oryzae
	A7ECR7	907557	908870	368	60.87	100.00	n/a	Putative uncharacterized protein - Sclerotinia sclerotiorum (strain ATCC 18683 / 1980 / Ss-1) (White mold) (Whetzelinia sclerotiorum)
	A6S0W9	907557	908834	374	62.04	94.39	n/a	Putative uncharacterized protein - Botryotinia fuckeliana (strain B05.10) (Noble rot fungus) (Botrytis cinerea)
	Q7SE60	907557	908870	388	54.12	100.00	n/a	Putative uncharacterized protein - Neurospora crassa
	Q5B7A5	907557	908846	382	56.20	95.03	n/a	Putative uncharacterized protein - Emericella nidulans (Aspergillus nidulans)
	Q5BGQ8	907557	908837	364	66.19	96.70	n/a	Putative uncharacterized protein - Emericella nidulans (Aspergillus nidulans)
	Q0CUW4	907801	908840	362	61.27	87.02	n/a	Putative uncharacterized protein - Aspergillus terreus (strain NIH 2624)
	A1CRY2	907557	908840	366	62.61	96.45	n/a	Phosphotransferase enzyme family domain protein - Aspergillus clavatus
	A1D4X3	907557	908861	364	63.64	99.73	n/a	Phosphotransferase enzyme family domain protein - Neosartorya fischeri (strain ATCC 1020 / DSM 3700 / NRRL 181) (Aspergillus fischerianus (strain ATCC 1020 / DSM 3700 / NRRL 181))
	Q0UUX5	907557	908870	397	83.20	95.97	n/a	Putative uncharacterized protein - Phaeosphaeria nodorum (Septoria nodorum)
	Q2URL6	907557	908861	364	61.16	99.73	n/a	Predicted aminoglycoside phosphotransferase - Aspergillus oryzae
	A7ECR7	907557	908870	368	60.87	100.00	n/a	Putative uncharacterized protein - Sclerotinia sclerotiorum (strain ATCC 18683 / 1980 / Ss-1) (White mold) (Whetzelinia sclerotiorum)
	A6S0W9	907557	908834	374	62.04	94.39	n/a	Putative uncharacterized protein - Botryotinia fuckeliana (strain B05.10) (Noble rot fungus) (Botrytis cinerea)
	Q7SE60	907557	908870	388	54.12	100.00	n/a	Putative uncharacterized protein - Neurospora crassa
	Q5B7A5	907557	908846	382	56.20	95.03	n/a	Putative uncharacterized protein - Emericella nidulans (Aspergillus nidulans)
	Q5BGQ8	907557	908837	364	66.19	96.70	n/a	Putative uncharacterized protein - Emericella nidulans (Aspergillus nidulans)
	A1CRY2	907557	908840	366	62.61	96.45	n/a	Phosphotransferase enzyme family domain protein - Aspergillus clavatus
	A1D4X3	907557	908861	364	63.64	99.73	n/a	Phosphotransferase enzyme family domain protein - Neosartorya fischeri (strain ATCC 1020 / DSM 3700 / NRRL 181) (Aspergillus fischerianus (strain ATCC 1020 / DSM 3700 / NRRL 181))
blastx_FNG31_prot	SNU04439.1	907557	908870	370	84.05	100.00	n/a	Stagonospora nodorum hypothetical protein translation
	AO090005000779	907557	908861	364	61.16	99.73	n/a	Aspergillus oryzae predicted aminoglycoside phosphotransferase
	SS1G_03106.1	907557	908870	368	60.87	100.00	n/a	sclerotinia_sclerotiorum hypothetical protein translation 369 aa
	BC1G_06343.1	907557	908834	374	62.04	94.39	n/a	Botrytis cinerea hypothetical protein translation 375 aa
	jgi:Triree:32352	907557	908870	356	59.55	100.00	n/a	Trichoderma reesei
	NCU00513.2	907557	908870	388	54.12	100.00	n/a	Neurospora crassa hypothetical protein translation 389 aa
	AN3575	907557	908846	382	56.20	95.03	n/a	Aspergillus nidulans AN3575.3 conserved hypothetical protein translation 383 aa
	AN0272	907557	908837	364	66.19	96.70	n/a	Aspergillus nidulans AN0272.3 conserved hypothetical protein translation 365 aa
	gi:70990378:ref:XP_750038.1:	907557	908861	364	63.36	99.73	n/a	Aspergillus fumigatus Af293 hypothetical protein Afu1g02880
	CIMG_04793.2	907557	908852	364	63.31	98.08	n/a	Coccidioides immitis hypothetical protein translation 365 aa
	SNU04439.1	907557	908870	370	84.05	100.00	n/a	Stagonospora nodorum hypothetical protein translation
	AO090005000779	907557	908861	364	61.16	99.73	n/a	Aspergillus oryzae predicted aminoglycoside phosphotransferase
	SS1G_03106.1	907557	908870	368	60.87	100.00	n/a	sclerotinia_sclerotiorum hypothetical protein translation 369 aa
	BC1G_06343.1	907557	908834	374	62.04	94.39	n/a	Botrytis cinerea hypothetical protein translation 375 aa
	jgi:Triree:32352	907557	908870	356	59.55	100.00	n/a	Trichoderma reesei
	NCU00513.2	907557	908870	388	54.12	100.00	n/a	Neurospora crassa hypothetical protein translation 389 aa
	AN3575	907557	908846	382	56.20	95.03	n/a	Aspergillus nidulans AN3575.3 conserved hypothetical protein translation 383 aa
	AN0272	907557	908837	364	66.19	96.70	n/a	Aspergillus nidulans AN0272.3 conserved hypothetical protein translation 365 aa
	gi:70990378:ref:XP_750038.1:	907557	908861	364	63.36	99.73	n/a	Aspergillus fumigatus Af293 hypothetical protein Afu1g02880
	CIMG_04793.2	907557	908852	364	63.31	98.08	n/a	Coccidioides immitis hypothetical protein translation 365 aa
blat_BES	no results
blastx_SN15proteins	gnl:WGS:AAGI:SNOT_04439.2:gb:EAT88199	907557	908870	397	83.20	95.97	n/a	n/a
	gnl:WGS:AAGI:SNOT_04416.2:gb:EAT88176	908142	908846	385	39.18	63.64	n/a	n/a
	gnl:WGS:AAGI:SNOT_04439.2:gb:EAT88199	907557	908870	397	83.20	95.97	n/a	n/a
RepeatMasker_SR	no results
RepeatMasker_LC	no results
sim4_Lm_allest	no results
sim4_lm_allest6_clctg	no results
sim4_cDNA_BHowlett	no results
blastx_uniprot_sprot	Q5ZHT1	907721	908831	777	39.74	39.51	n/a	Acyl-CoA dehydrogenase family member 11 - Gallus gallus (Chicken)
	Q6JQN1	907718	908828	1059	38.08	28.52	n/a	Acyl-CoA dehydrogenase family member 10 - Homo sapiens (Human)
	Q80XL6	907733	908831	779	40.79	39.02	n/a	Acyl-CoA dehydrogenase family member 11 - Mus musculus (Mouse)
	Q5R778	907733	908831	781	38.74	38.67	n/a	Acyl-CoA dehydrogenase family member 11 - Pongo pygmaeus (Orangutan)
	Q8K370	907718	908828	1069	38.33	28.06	n/a	Acyl-CoA dehydrogenase family member 10 - Mus musculus (Mouse)
	Q709F0	907733	908831	780	37.95	38.85	n/a	Acyl-CoA dehydrogenase family member 11 - Homo sapiens (Human)
REPET	no results
MUMer_show_coords_lm_WA74	no results