GO Term : GO:1990774 tumor necrosis factor secretion GO

Namespace  biological_process Obsolete  false
description  The regulated release of tumor necrosis factor from a cell. Tumor necrosis factor is an inflammatory cytokine produced by macrophages/monocytes during acute inflammation and which is responsible for a diverse range of signaling events within cells, leading to necrosis or apoptosis.

0 Cross References

1 Ontology

Name
GO

26 Parents

Identifier Name Description
GO:0006810 transport The directed movement of substances (such as macromolecules, small molecules, ions) into, out of or within a cell, or between cells, or within a multicellular organism by means of some agent such as a transporter or pore.
GO:0015031 protein transport The directed movement of proteins into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.
GO:1902578 single-organism localization A localization which involves only one organism.
GO:0044699 single-organism process A biological process that involves only one organism.
GO:0009987 cellular process Any process that is carried out at the cellular level, but not necessarily restricted to a single cell. For example, cell communication occurs among more than one cell, but occurs at the cellular level.
GO:0051641 cellular localization A localization process that takes place at the cellular level; as a result of a cellular localization process, a substance or cellular entity, such as a protein complex or organelle, is transported to, and/or maintained in, a specific location within or in the membrane of a cell.
GO:0008150 biological_process Any process specifically pertinent to the functioning of integrated living units: cells, tissues, organs, and organisms. A process is a collection of molecular events with a defined beginning and end.
GO:0051179 localization Any process in which a cell, a substance, or a cellular entity, such as a protein complex or organelle, is transported to or maintained in a specific location.
GO:0044763 single-organism cellular process Any process that is carried out at the cellular level, occurring within a single organism.
GO:0044765 single-organism transport The directed movement of substances (such as macromolecules, small molecules, ions) into, out of or within a cell, or between cells, or within a multicellular organism by means of some agent such as a transporter or pore, involving a single organism.
GO:0071702 organic substance transport The directed movement of organic substances into, out of or within a cell, or between cells, or within a multicellular organism by means of some agent such as a transporter or pore. An organic substance is a molecular entity that contains carbon.
GO:0051234 establishment of localization The directed movement of a cell, substance or cellular entity, such as a protein complex or organelle, to a specific location.
GO:0045184 establishment of protein localization The directed movement of a protein to a specific location.
GO:0008104 protein localization Any process in which a protein is transported to, or maintained in, a specific location.
GO:0051649 establishment of localization in cell The directed movement of a substance or cellular entity, such as a protein complex or organelle, to a specific location within, or in the membrane of, a cell.
GO:0033036 macromolecule localization Any process in which a macromolecule is transported to, or maintained in, a specific location.
GO:0044707 single-multicellular organism process A biological process occurring within a single, multicellular organism.
GO:0032501 multicellular organismal process Any biological process, occurring at the level of a multicellular organism, pertinent to its function.
GO:0046903 secretion The controlled release of a substance by a cell or a tissue.
GO:0001816 cytokine production The appearance of a cytokine due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels.
GO:0032940 secretion by cell The controlled release of a substance by a cell.
GO:0009306 protein secretion The controlled release of proteins from a cell.
GO:0050663 cytokine secretion The regulated release of cytokines from a cell. Cytokines are any of a group of proteins that function to control the survival, growth and differentiation of tissues and cells, and which have autocrine and paracrine activity.
GO:0071706 tumor necrosis factor superfamily cytokine production The appearance of any member of the TNF superfamily due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels.
GO:0032640 tumor necrosis factor production The appearance of tumor necrosis factor due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels.
GO:1990774 tumor necrosis factor secretion The regulated release of tumor necrosis factor from a cell. Tumor necrosis factor is an inflammatory cytokine produced by macrophages/monocytes during acute inflammation and which is responsible for a diverse range of signaling events within cells, leading to necrosis or apoptosis.

0 Protein

35 Relations

Relationship
Parent Term . Identifier

Child Term . Identifier
regulates GO:1990774 GO:1904467
negatively regulates GO:1990774 GO:1904468
regulates GO:1990774 GO:1904468
positively regulates GO:1990774 GO:1904469
regulates GO:1990774 GO:1904469
part of GO:0032640 GO:1990774
is_a GO:0050663 GO:1990774
is_a GO:0015031 GO:1990774
is_a GO:0006810 GO:1990774
is_a GO:0044699 GO:1990774
is_a GO:0051179 GO:1990774
is_a GO:0008104 GO:1990774
part of GO:0044699 GO:1990774
is_a GO:0051649 GO:1990774
part of GO:0071706 GO:1990774
is_a GO:0033036 GO:1990774
part of GO:0051179 GO:1990774
part of GO:0051641 GO:1990774
part of GO:0008104 GO:1990774
part of GO:0032501 GO:1990774
is_a GO:0009306 GO:1990774
is_a GO:0009987 GO:1990774
is_a GO:1902578 GO:1990774
part of GO:0044707 GO:1990774
is_a GO:0032940 GO:1990774
is_a GO:0045184 GO:1990774
is_a GO:0044763 GO:1990774
is_a GO:0044765 GO:1990774
is_a GO:0046903 GO:1990774
is_a GO:0051234 GO:1990774

7 Synonyms

Name Type
TNF-alpha secretion synonym
TNF superfamily, member 2 secretion synonym
tumor necrosis factor alpha secretion synonym
Tnfa secretion synonym
TNF secretion synonym
cachectin secretion synonym
tumor necrosis factor ligand superfamily member 2 secretion synonym