GO Term : GO:0090398 cellular senescence GO

Namespace  biological_process Obsolete  false
description  A cell aging process stimulated in response to cellular stress, whereby normal cells lose the ability to divide through irreversible cell cycle arrest.

0 Cross References

1 Ontology

Name
GO

13 Parents

Identifier Name Description
GO:0032502 developmental process A biological process whose specific outcome is the progression of an integrated living unit: an anatomical structure (which may be a subcellular structure, cell, tissue, or organ), or organism over time from an initial condition to a later condition.
GO:0006950 response to stress Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a disturbance in organismal or cellular homeostasis, usually, but not necessarily, exogenous (e.g. temperature, humidity, ionizing radiation).
GO:0051716 cellular response to stimulus Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus. The process begins with detection of the stimulus by a cell and ends with a change in state or activity or the cell.
GO:0044699 single-organism process A biological process that involves only one organism.
GO:0009987 cellular process Any process that is carried out at the cellular level, but not necessarily restricted to a single cell. For example, cell communication occurs among more than one cell, but occurs at the cellular level.
GO:0008150 biological_process Any process specifically pertinent to the functioning of integrated living units: cells, tissues, organs, and organisms. A process is a collection of molecular events with a defined beginning and end.
GO:0044763 single-organism cellular process Any process that is carried out at the cellular level, occurring within a single organism.
GO:0050896 response to stimulus Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus. The process begins with detection of the stimulus and ends with a change in state or activity or the cell or organism.
GO:0033554 cellular response to stress Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus indicating the organism is under stress. The stress is usually, but not necessarily, exogenous (e.g. temperature, humidity, ionizing radiation).
GO:0044767 single-organism developmental process A biological process whose specific outcome is the progression of an integrated living unit: an anatomical structure (which may be a subcellular structure, cell, tissue, or organ), or organism over time from an initial condition to a later condition, involving only one organism.
GO:0007569 cell aging An aging process that has as participant a cell after a cell has stopped dividing. Cell aging may occur when a cell has temporarily stopped dividing through cell cycle arrest (GO:0007050) or when a cell has permanently stopped dividing, in which case it is undergoing cellular senescence (GO:0090398). May precede cell death (GO:0008219) and succeed cell maturation (GO:0048469).
GO:0007568 aging A developmental process that is a deterioration and loss of function over time. Aging includes loss of functions such as resistance to disease, homeostasis, and fertility, as well as wear and tear. Aging includes cellular senescence, but is more inclusive. May precede death (GO:0016265) and may succeed developmental maturation (GO:0021700).
GO:0090398 cellular senescence A cell aging process stimulated in response to cellular stress, whereby normal cells lose the ability to divide through irreversible cell cycle arrest.

0 Protein

21 Relations

Relationship
Parent Term . Identifier

Child Term . Identifier
is_a GO:0033554 GO:0090398
is_a GO:0007569 GO:0090398
is_a GO:0008150 GO:0090398
is_a GO:0006950 GO:0090398
is_a GO:0032502 GO:0090398
is_a GO:0009987 GO:0090398
is_a GO:0051716 GO:0090398
is_a GO:0044699 GO:0090398
is_a GO:0044767 GO:0090398
is_a GO:0007568 GO:0090398
is_a GO:0050896 GO:0090398
is_a GO:0044763 GO:0090398
is_a GO:0090398 GO:0090400
is_a GO:0090398 GO:0090401
is_a GO:0090398 GO:0090402
is_a GO:0090398 GO:0090403
regulates GO:0090398 GO:2000772
negatively regulates GO:0090398 GO:2000773
regulates GO:0090398 GO:2000773
positively regulates GO:0090398 GO:2000774
regulates GO:0090398 GO:2000774

0 Synonyms