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GO:0007165
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signal transduction
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The cellular process in which a signal is conveyed to trigger a change in the activity or state of a cell. Signal transduction begins with reception of a signal (e.g. a ligand binding to a receptor or receptor activation by a stimulus such as light), or for signal transduction in the absence of ligand, signal-withdrawal or the activity of a constitutively active receptor. Signal transduction ends with regulation of a downstream cellular process, e.g. regulation of transcription or regulation of a metabolic process. Signal transduction covers signaling from receptors located on the surface of the cell and signaling via molecules located within the cell. For signaling between cells, signal transduction is restricted to events at and within the receiving cell. |
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GO:0007186
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G-protein coupled receptor signaling pathway
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A series of molecular signals that proceeds with an activated receptor promoting the exchange of GDP for GTP on the alpha-subunit of an associated heterotrimeric G-protein complex. The GTP-bound activated alpha-G-protein then dissociates from the beta- and gamma-subunits to further transmit the signal within the cell. The pathway begins with receptor-ligand interaction, or for basal GPCR signaling the pathway begins with the receptor activating its G protein in the absence of an agonist, and ends with regulation of a downstream cellular process, e.g. transcription. The pathway can start from the plasma membrane, Golgi or nuclear membrane (PMID:24568158 and PMID:16902576). |
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GO:0051716
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cellular response to stimulus
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Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus. The process begins with detection of the stimulus by a cell and ends with a change in state or activity or the cell. |
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GO:0044699
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single-organism process
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A biological process that involves only one organism. |
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GO:0009987
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cellular process
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Any process that is carried out at the cellular level, but not necessarily restricted to a single cell. For example, cell communication occurs among more than one cell, but occurs at the cellular level. |
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GO:0008150
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biological_process
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Any process specifically pertinent to the functioning of integrated living units: cells, tissues, organs, and organisms. A process is a collection of molecular events with a defined beginning and end. |
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GO:0044763
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single-organism cellular process
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Any process that is carried out at the cellular level, occurring within a single organism. |
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GO:0050896
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response to stimulus
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Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus. The process begins with detection of the stimulus and ends with a change in state or activity or the cell or organism. |
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GO:0065007
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biological regulation
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Any process that modulates a measurable attribute of any biological process, quality or function. |
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GO:0050794
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regulation of cellular process
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Any process that modulates the frequency, rate or extent of a cellular process, any of those that are carried out at the cellular level, but are not necessarily restricted to a single cell. For example, cell communication occurs among more than one cell, but occurs at the cellular level. |
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GO:0050789
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regulation of biological process
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Any process that modulates the frequency, rate or extent of a biological process. Biological processes are regulated by many means; examples include the control of gene expression, protein modification or interaction with a protein or substrate molecule. |
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GO:0007154
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cell communication
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Any process that mediates interactions between a cell and its surroundings. Encompasses interactions such as signaling or attachment between one cell and another cell, between a cell and an extracellular matrix, or between a cell and any other aspect of its environment. |
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GO:0048519
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negative regulation of biological process
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Any process that stops, prevents, or reduces the frequency, rate or extent of a biological process. Biological processes are regulated by many means; examples include the control of gene expression, protein modification or interaction with a protein or substrate molecule. |
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GO:0044700
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single organism signaling
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A signaling process occurring within a single organism. |
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GO:0023052
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signaling
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The entirety of a process in which information is transmitted within a biological system. This process begins with an active signal and ends when a cellular response has been triggered. |
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GO:0044707
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single-multicellular organism process
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A biological process occurring within a single, multicellular organism. |
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GO:0032501
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multicellular organismal process
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Any biological process, occurring at the level of a multicellular organism, pertinent to its function. |
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GO:0065008
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regulation of biological quality
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Any process that modulates a qualitative or quantitative trait of a biological quality. A biological quality is a measurable attribute of an organism or part of an organism, such as size, mass, shape, color, etc. |
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GO:0003008
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system process
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A multicellular organismal process carried out by any of the organs or tissues in an organ system. An organ system is a regularly interacting or interdependent group of organs or tissues that work together to carry out a biological objective. |
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GO:0050877
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neurological system process
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A organ system process carried out by any of the organs or tissues of neurological system. |
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GO:0051239
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regulation of multicellular organismal process
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Any process that modulates the frequency, rate or extent of a multicellular organismal process, the processes pertinent to the function of a multicellular organism above the cellular level; includes the integrated processes of tissues and organs. |
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GO:0051241
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negative regulation of multicellular organismal process
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Any process that stops, prevents, or reduces the frequency, rate or extent of an organismal process, the processes pertinent to the function of an organism above the cellular level; includes the integrated processes of tissues and organs. |
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GO:0001976
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neurological system process involved in regulation of systemic arterial blood pressure
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The regulation of blood pressure mediated by detection of stimuli and a neurological response. |
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GO:0003073
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regulation of systemic arterial blood pressure
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The process that modulates the force with which blood travels through the systemic arterial circulatory system. The process is controlled by a balance of processes that increase pressure and decrease pressure. |
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GO:0008015
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blood circulation
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The flow of blood through the body of an animal, enabling the transport of nutrients to the tissues and the removal of waste products. |
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GO:0008217
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regulation of blood pressure
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Any process that modulates the force with which blood travels through the circulatory system. The process is controlled by a balance of processes that increase pressure and decrease pressure. |
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GO:0003013
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circulatory system process
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A organ system process carried out by any of the organs or tissues of the circulatory system. The circulatory system is an organ system that moves extracellular fluids to and from tissue within a multicellular organism. |
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GO:0010459
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negative regulation of heart rate
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Any process that stops, prevents or reduces the frequency or rate of heart contraction. |
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GO:0002027
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regulation of heart rate
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Any process that modulates the frequency or rate of heart contraction. |
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GO:0003015
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heart process
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A circulatory system process carried out by the heart. The heart is a hollow, muscular organ, which, by contracting rhythmically, keeps up the circulation of the blood. The heart is a hollow, muscular organ, which, by contracting rhythmically, keeps up the circulation of the blood. |
