GO Term : GO:0051482 positive regulation of cytosolic calcium ion concentration involved in phospholipase C-activating G-protein coupled signaling pathway GO
Namespace  biological_process Obsolete  false
description  Any process that increases the concentration of calcium ions in the cytosol that occurs as part of a PLC-activating G-protein coupled receptor signaling pathway. G-protein-activated PLC hydrolyses phosphatidylinositol-bisphosphate (PIP2) to release diacylglycerol (DAG) and inositol trisphosphate (IP3). IP3 then binds to calcium release channels in the endoplasmic reticulum (ER) to trigger calcium ion release into the cytosol.
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0 Cross References

1 Ontology

Name
GO

34 Parents

Identifier Name Description
GO:0007165 signal transduction The cellular process in which a signal is conveyed to trigger a change in the activity or state of a cell. Signal transduction begins with reception of a signal (e.g. a ligand binding to a receptor or receptor activation by a stimulus such as light), or for signal transduction in the absence of ligand, signal-withdrawal or the activity of a constitutively active receptor. Signal transduction ends with regulation of a downstream cellular process, e.g. regulation of transcription or regulation of a metabolic process. Signal transduction covers signaling from receptors located on the surface of the cell and signaling via molecules located within the cell. For signaling between cells, signal transduction is restricted to events at and within the receiving cell.
GO:0007186 G-protein coupled receptor signaling pathway A series of molecular signals that proceeds with an activated receptor promoting the exchange of GDP for GTP on the alpha-subunit of an associated heterotrimeric G-protein complex. The GTP-bound activated alpha-G-protein then dissociates from the beta- and gamma-subunits to further transmit the signal within the cell. The pathway begins with receptor-ligand interaction, or for basal GPCR signaling the pathway begins with the receptor activating its G protein in the absence of an agonist, and ends with regulation of a downstream cellular process, e.g. transcription. The pathway can start from the plasma membrane, Golgi or nuclear membrane (PMID:24568158 and PMID:16902576).
GO:0051716 cellular response to stimulus Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus. The process begins with detection of the stimulus by a cell and ends with a change in state or activity or the cell.
GO:0006873 cellular ion homeostasis Any process involved in the maintenance of an internal steady state of ions at the level of a cell.
GO:0044699 single-organism process A biological process that involves only one organism.
GO:0009987 cellular process Any process that is carried out at the cellular level, but not necessarily restricted to a single cell. For example, cell communication occurs among more than one cell, but occurs at the cellular level.
GO:0008150 biological_process Any process specifically pertinent to the functioning of integrated living units: cells, tissues, organs, and organisms. A process is a collection of molecular events with a defined beginning and end.
GO:0044763 single-organism cellular process Any process that is carried out at the cellular level, occurring within a single organism.
GO:0050896 response to stimulus Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus. The process begins with detection of the stimulus and ends with a change in state or activity or the cell or organism.
GO:0065007 biological regulation Any process that modulates a measurable attribute of any biological process, quality or function.
GO:0050794 regulation of cellular process Any process that modulates the frequency, rate or extent of a cellular process, any of those that are carried out at the cellular level, but are not necessarily restricted to a single cell. For example, cell communication occurs among more than one cell, but occurs at the cellular level.
GO:0050789 regulation of biological process Any process that modulates the frequency, rate or extent of a biological process. Biological processes are regulated by many means; examples include the control of gene expression, protein modification or interaction with a protein or substrate molecule.
GO:0007154 cell communication Any process that mediates interactions between a cell and its surroundings. Encompasses interactions such as signaling or attachment between one cell and another cell, between a cell and an extracellular matrix, or between a cell and any other aspect of its environment.
GO:0044700 single organism signaling A signaling process occurring within a single organism.
GO:0023052 signaling The entirety of a process in which information is transmitted within a biological system. This process begins with an active signal and ends when a cellular response has been triggered.
GO:0042592 homeostatic process Any biological process involved in the maintenance of an internal steady state.
GO:0065008 regulation of biological quality Any process that modulates a qualitative or quantitative trait of a biological quality. A biological quality is a measurable attribute of an organism or part of an organism, such as size, mass, shape, color, etc.
GO:0055082 cellular chemical homeostasis Any biological process involved in the maintenance of an internal steady state of a chemical at the level of the cell.
GO:0048878 chemical homeostasis Any biological process involved in the maintenance of an internal steady state of a chemical.
GO:0019725 cellular homeostasis Any process involved in the maintenance of an internal steady state at the level of the cell.
GO:0050801 ion homeostasis Any process involved in the maintenance of an internal steady state of ions within an organism or cell.
GO:0006874 cellular calcium ion homeostasis Any process involved in the maintenance of an internal steady state of calcium ions at the level of a cell.
GO:0006875 cellular metal ion homeostasis Any process involved in the maintenance of an internal steady state of metal ions at the level of a cell.
GO:0055074 calcium ion homeostasis Any process involved in the maintenance of an internal steady state of calcium ions within an organism or cell.
GO:0072503 cellular divalent inorganic cation homeostasis Any process involved in the maintenance of an internal steady state of divalent cations at the level of a cell.
GO:0098771 inorganic ion homeostasis Any process involved in the maintenance of an internal steady state of inorganic ions within an organism or cell.
GO:0055065 metal ion homeostasis Any process involved in the maintenance of an internal steady state of metal ions within an organism or cell.
GO:0055080 cation homeostasis Any process involved in the maintenance of an internal steady state of cations within an organism or cell.
GO:0030003 cellular cation homeostasis Any process involved in the maintenance of an internal steady state of cations at the level of a cell.
GO:0072507 divalent inorganic cation homeostasis Any process involved in the maintenance of an internal steady state of divalent cations within an organism or cell.

0 Protein

38 Relations

Relationship
Parent Term . Identifier
Child Term . Identifier
part of GO:0007200 GO:0051482
is_a GO:0007204 GO:0051482
is_a GO:0065007 GO:0051482
part of GO:0050789 GO:0051482
is_a GO:0065008 GO:0051482
part of GO:0008150 GO:0051482
is_a GO:0019725 GO:0051482
is_a GO:0009987 GO:0051482
is_a GO:0044699 GO:0051482
part of GO:0007186 GO:0051482
is_a GO:0008150 GO:0051482
is_a GO:0044763 GO:0051482
is_a GO:0055074 GO:0051482
part of GO:0044699 GO:0051482
part of GO:0007154 GO:0051482
part of GO:0065007 GO:0051482
part of GO:0050896 GO:0051482
is_a GO:0030003 GO:0051482
part of GO:0050794 GO:0051482
part of GO:0044700 GO:0051482
is_a GO:0050801 GO:0051482
is_a GO:0098771 GO:0051482
is_a GO:0042592 GO:0051482
is_a GO:0055082 GO:0051482
is_a GO:0006875 GO:0051482
is_a GO:0055065 GO:0051482
part of GO:0007165 GO:0051482
is_a GO:0006874 GO:0051482
is_a GO:0006873 GO:0051482
part of GO:0051716 GO:0051482

7 Synonyms

Name Type
elevation of cytoplasmic calcium ion concentration during G-protein signaling, coupled to IP3 second messenger (phospholipase C activating) synonym
elevation of cytoplasmic calcium ion concentration during G-protein signalling, coupled to IP3 second messenger (phospholipase C activating) synonym
elevation of calcium ion concentration in cytoplasm during G-protein signaling, coupled to IP3 second messenger (phospholipase C activating) synonym
elevation of calcium ion concentration in cytosol during G-protein signaling, coupled to IP3 second messenger (phospholipase C activating) synonym
elevation of cytosolic calcium ion concentration involved in phospholipase C-activating G-protein coupled signaling pathway synonym
elevation of cytosolic calcium ion concentration during G-protein signalling, coupled to IP3 second messenger (phospholipase C activating) synonym
elevation of cytosolic calcium ion concentration involved in G-protein signaling coupled to IP3 second messenger synonym