GO Term : GO:0050983 deoxyhypusine biosynthetic process from spermidine GO

Namespace  biological_process Obsolete  false
description  The chemical reactions resulting in the formation of deoxyhypusine from spermidine by the enzyme [eIF-5A]-deoxyhypusine synthase. The reaction occurs in four steps: 1. spermidine + NAD+ = dehydrospermidine + NADH + H+; 2. dehydrospermidine + [enzyme]-lysine = 1,3-diaminopropane + [enzyme]-lysine-N6=CH(CH2)3NH2; 3. [enzyme]-lysine-N6=CH(CH2)3NH2 = [eIF-5A]-lysine-N6=CH(CH2)3NH2; 4. [eIF-5A]-lysine-N6=CH(CH2)3NH2 + NADH + H+ = [eIF-5A]-deoxyhypusine + NAD+.

0 Cross References

1 Ontology

Name
GO

45 Parents

Identifier Name Description
GO:0008152 metabolic process The chemical reactions and pathways, including anabolism and catabolism, by which living organisms transform chemical substances. Metabolic processes typically transform small molecules, but also include macromolecular processes such as DNA repair and replication, and protein synthesis and degradation.
GO:0009058 biosynthetic process The chemical reactions and pathways resulting in the formation of substances; typically the energy-requiring part of metabolism in which simpler substances are transformed into more complex ones.
GO:0044237 cellular metabolic process The chemical reactions and pathways by which individual cells transform chemical substances.
GO:0006595 polyamine metabolic process The chemical reactions and pathways involving polyamines, any organic compound containing two or more amino groups.
GO:0019752 carboxylic acid metabolic process The chemical reactions and pathways involving carboxylic acids, any organic acid containing one or more carboxyl (COOH) groups or anions (COO-).
GO:0071704 organic substance metabolic process The chemical reactions and pathways involving an organic substance, any molecular entity containing carbon.
GO:0008652 cellular amino acid biosynthetic process The chemical reactions and pathways resulting in the formation of amino acids, organic acids containing one or more amino substituents.
GO:0006520 cellular amino acid metabolic process The chemical reactions and pathways involving amino acids, carboxylic acids containing one or more amino groups, as carried out by individual cells.
GO:0042398 cellular modified amino acid biosynthetic process The chemical reactions and pathways resulting in the formation of compounds derived from amino acids, organic acids containing one or more amino substituents.
GO:0006807 nitrogen compound metabolic process The chemical reactions and pathways involving organic or inorganic compounds that contain nitrogen, including (but not limited to) nitrogen fixation, nitrification, denitrification, assimilatory/dissimilatory nitrate reduction and the interconversion of nitrogenous organic matter and ammonium.
GO:0044249 cellular biosynthetic process The chemical reactions and pathways resulting in the formation of substances, carried out by individual cells.
GO:0009308 amine metabolic process The chemical reactions and pathways involving any organic compound that is weakly basic in character and contains an amino or a substituted amino group, as carried out by individual cells. Amines are called primary, secondary, or tertiary according to whether one, two, or three carbon atoms are attached to the nitrogen atom.
GO:0044238 primary metabolic process The chemical reactions and pathways involving those compounds which are formed as a part of the normal anabolic and catabolic processes. These processes take place in most, if not all, cells of the organism.
GO:0044699 single-organism process A biological process that involves only one organism.
GO:0009987 cellular process Any process that is carried out at the cellular level, but not necessarily restricted to a single cell. For example, cell communication occurs among more than one cell, but occurs at the cellular level.
GO:0008150 biological_process Any process specifically pertinent to the functioning of integrated living units: cells, tissues, organs, and organisms. A process is a collection of molecular events with a defined beginning and end.
GO:0044763 single-organism cellular process Any process that is carried out at the cellular level, occurring within a single organism.
GO:0034641 cellular nitrogen compound metabolic process The chemical reactions and pathways involving various organic and inorganic nitrogenous compounds, as carried out by individual cells.
GO:0044710 single-organism metabolic process A metabolic process - chemical reactions and pathways, including anabolism and catabolism, by which living organisms transform chemical substances - which involves a single organism.
GO:1901576 organic substance biosynthetic process The chemical reactions and pathways resulting in the formation of an organic substance, any molecular entity containing carbon.
GO:0044711 single-organism biosynthetic process A biosynthetic process - chemical reactions and pathways resulting in the formation of substances - involving a single organism.
GO:0009056 catabolic process The chemical reactions and pathways resulting in the breakdown of substances, including the breakdown of carbon compounds with the liberation of energy for use by the cell or organism.
GO:1901575 organic substance catabolic process The chemical reactions and pathways resulting in the breakdown of an organic substance, any molecular entity containing carbon.
GO:0044712 single-organism catabolic process A catabolic process - chemical reactions and pathways resulting in the breakdown of substances - which involves a single organism.
GO:0006082 organic acid metabolic process The chemical reactions and pathways involving organic acids, any acidic compound containing carbon in covalent linkage.
GO:0043436 oxoacid metabolic process The chemical reactions and pathways involving any oxoacid; an oxoacid is a compound which contains oxygen, at least one other element, and at least one hydrogen bound to oxygen, and which produces a conjugate base by loss of positive hydrogen ion(s) (hydrons).
GO:0044281 small molecule metabolic process The chemical reactions and pathways involving small molecules, any low molecular weight, monomeric, non-encoded molecule.
GO:1901566 organonitrogen compound biosynthetic process The chemical reactions and pathways resulting in the formation of organonitrogen compound.
GO:1901564 organonitrogen compound metabolic process The chemical reactions and pathways involving organonitrogen compound.
GO:0006575 cellular modified amino acid metabolic process The chemical reactions and pathways involving compounds derived from amino acids, organic acids containing one or more amino substituents.

0 Protein

44 Relations

Relationship
Parent Term . Identifier

Child Term . Identifier
is_a GO:0046203 GO:0050983
is_a GO:0044712 GO:0050983
is_a GO:0042398 GO:0050983
is_a GO:1901607 GO:0050983
is_a GO:0043436 GO:0050983
is_a GO:0006575 GO:0050983
is_a GO:0006576 GO:0050983
is_a GO:0006595 GO:0050983
is_a GO:1901576 GO:0050983
is_a GO:0044249 GO:0050983
is_a GO:0006598 GO:0050983
is_a GO:0044699 GO:0050983
is_a GO:0071704 GO:0050983
is_a GO:0009308 GO:0050983
is_a GO:0044106 GO:0050983
is_a GO:1901575 GO:0050983
is_a GO:0006807 GO:0050983
is_a GO:0044711 GO:0050983
is_a GO:0044710 GO:0050983
is_a GO:0019752 GO:0050983
is_a GO:0006520 GO:0050983
is_a GO:0008652 GO:0050983
is_a GO:0009987 GO:0050983
is_a GO:1901605 GO:0050983
is_a GO:0008216 GO:0050983
is_a GO:0042402 GO:0050983
is_a GO:0006082 GO:0050983
is_a GO:0044238 GO:0050983
is_a GO:0034641 GO:0050983
is_a GO:0097164 GO:0050983

9 Synonyms

Name Type
[eIF-5A]-deoxyhypusine synthase activity synonym
deoxyhypusine anabolism from spermidine, using deoxyhypusine synthase synonym
deoxyhypusine biosynthesis from spermidine, using deoxyhypusine synthase synonym
deoxyhypusine biosynthetic process from spermidine, using deoxyhypusine synthase synonym
(4-aminobutyl)lysine synthase activity synonym
spermidine breakdown to deoxyhypusine, using deoxyhypusine synthase synonym
deoxyhypusine formation from spermidine, using deoxyhypusine synthase synonym
spermidine degradation to deoxyhypusine, using deoxyhypusine synthase synonym
spermidine catabolic process to deoxyhypusine, using deoxyhypusine synthase synonym