GO Term : GO:0046849 bone remodeling GO

Namespace  biological_process Obsolete  false
description  The continuous turnover of bone matrix and mineral that involves first, an increase in resorption (osteoclastic activity) and later, reactive bone formation (osteoblastic activity). The process of bone remodeling takes place in the adult skeleton at discrete foci. The process ensures the mechanical integrity of the skeleton throughout life and plays an important role in calcium homeostasis. An imbalance in the regulation of bone resorption and bone formation results in many of the metabolic bone diseases, such as osteoporosis.

0 Cross References

1 Ontology

Name
GO

6 Parents

Identifier Name Description
GO:0044699 single-organism process A biological process that involves only one organism.
GO:0008150 biological_process Any process specifically pertinent to the functioning of integrated living units: cells, tissues, organs, and organisms. A process is a collection of molecular events with a defined beginning and end.
GO:0044707 single-multicellular organism process A biological process occurring within a single, multicellular organism.
GO:0032501 multicellular organismal process Any biological process, occurring at the level of a multicellular organism, pertinent to its function.
GO:0048771 tissue remodeling The reorganization or renovation of existing tissues. This process can either change the characteristics of a tissue such as in blood vessel remodeling, or result in the dynamic equilibrium of a tissue such as in bone remodeling.
GO:0046849 bone remodeling The continuous turnover of bone matrix and mineral that involves first, an increase in resorption (osteoclastic activity) and later, reactive bone formation (osteoblastic activity). The process of bone remodeling takes place in the adult skeleton at discrete foci. The process ensures the mechanical integrity of the skeleton throughout life and plays an important role in calcium homeostasis. An imbalance in the regulation of bone resorption and bone formation results in many of the metabolic bone diseases, such as osteoporosis.

0 Protein

17 Relations

Relationship
Parent Term . Identifier

Child Term . Identifier
part of GO:0046849 GO:0043932
regulates GO:0046849 GO:0045124
part of GO:0046849 GO:0045453
negatively regulates GO:0046849 GO:0045779
regulates GO:0046849 GO:0045779
positively regulates GO:0046849 GO:0045780
regulates GO:0046849 GO:0045780
is_a GO:0048771 GO:0046849
is_a GO:0032501 GO:0046849
is_a GO:0044699 GO:0046849
is_a GO:0008150 GO:0046849
is_a GO:0044707 GO:0046849
regulates GO:0046849 GO:0046850
negatively regulates GO:0046849 GO:0046851
regulates GO:0046849 GO:0046851
positively regulates GO:0046849 GO:0046852
regulates GO:0046849 GO:0046852

1 Synonyms

Name Type
bone remodelling synonym