GO Term : GO:0034292 pinholin activity GO

Namespace  molecular_function Obsolete  false
description  A compound function consisting of the regulated formation of a pore via oligomerisation of an existing pool of subunits in the plasma membrane. The resulting ion channel activity indirectly allows endolysin (murein hydrolyases) to access their cell wall substrate by collapsing the proton motive force (PMF) across the membrane, allowing the endolysin to fold to an active form and hydrolyze bonds in the peptidoglycan cell wall.

0 Cross References

1 Ontology

Name
GO

12 Parents

Identifier Name Description
GO:0022857 transmembrane transporter activity Enables the transfer of a substance from one side of a membrane to the other.
GO:0022891 substrate-specific transmembrane transporter activity Enables the transfer of a specific substance or group of related substances from one side of a membrane to the other.
GO:0005215 transporter activity Enables the directed movement of substances (such as macromolecules, small molecules, ions) into, out of or within a cell, or between cells.
GO:0005216 ion channel activity Enables the facilitated diffusion of an ion (by an energy-independent process) by passage through a transmembrane aqueous pore or channel without evidence for a carrier-mediated mechanism. May be either selective (it enables passage of a specific ion only) or non-selective (it enables passage of two or more ions of same charge but different size).
GO:0015075 ion transmembrane transporter activity Enables the transfer of an ion from one side of a membrane to the other.
GO:0003674 molecular_function Elemental activities, such as catalysis or binding, describing the actions of a gene product at the molecular level. A given gene product may exhibit one or more molecular functions.
GO:0022892 substrate-specific transporter activity Enables the directed movement of a specific substance or group of related substances (such as macromolecules, small molecules, ions) into, out of or within a cell, or between cells.
GO:0022803 passive transmembrane transporter activity Enables the transfer of a solute from one side of the membrane to the other, down the solute's concentration gradient.
GO:0015267 channel activity Enables the energy-independent facilitated diffusion, mediated by passage of a solute through a transmembrane aqueous pore or channel. Stereospecificity is not exhibited but this transport may be specific for a particular molecular species or class of molecules.
GO:0022838 substrate-specific channel activity Enables the energy-independent facilitated diffusion, mediated by passage of a specific solute through a transmembrane aqueous pore or channel. Stereospecificity is not exhibited but this transport may be specific for a particular molecular species or class of molecules.
GO:0034290 holin activity A compound function consisting of the regulated formation of a pore via oligomerisation of an existing pool of subunits in the plasma membrane. The resulting channel activity directly or indirectly allows murein hydrolyases to access their cell wall substrate.
GO:0034292 pinholin activity A compound function consisting of the regulated formation of a pore via oligomerisation of an existing pool of subunits in the plasma membrane. The resulting ion channel activity indirectly allows endolysin (murein hydrolyases) to access their cell wall substrate by collapsing the proton motive force (PMF) across the membrane, allowing the endolysin to fold to an active form and hydrolyze bonds in the peptidoglycan cell wall.

0 Protein

11 Relations

Relationship
Parent Term . Identifier

Child Term . Identifier
is_a GO:0005216 GO:0034292
is_a GO:0034290 GO:0034292
is_a GO:0022891 GO:0034292
is_a GO:0003674 GO:0034292
is_a GO:0022892 GO:0034292
is_a GO:0022838 GO:0034292
is_a GO:0015267 GO:0034292
is_a GO:0022803 GO:0034292
is_a GO:0005215 GO:0034292
is_a GO:0015075 GO:0034292
is_a GO:0022857 GO:0034292

0 Synonyms