GO Term : GO:0031639 plasminogen activation GO

Namespace  biological_process Obsolete  false
description  The process in which inactive plasminogen is processed to active plasmin. This process includes cleavage at an internal Arg-Val site to form an N-terminal A-chain and C-terminal B-chain held together by a disulfide bond, and can include further proteolytic cleavage events to remove the preactivation peptide.

0 Cross References

1 Ontology

Name
GO

12 Parents

Identifier Name Description
GO:0008152 metabolic process The chemical reactions and pathways, including anabolism and catabolism, by which living organisms transform chemical substances. Metabolic processes typically transform small molecules, but also include macromolecular processes such as DNA repair and replication, and protein synthesis and degradation.
GO:0006508 proteolysis The hydrolysis of proteins into smaller polypeptides and/or amino acids by cleavage of their peptide bonds.
GO:0071704 organic substance metabolic process The chemical reactions and pathways involving an organic substance, any molecular entity containing carbon.
GO:0019538 protein metabolic process The chemical reactions and pathways involving a specific protein, rather than of proteins in general. Includes protein modification.
GO:0016485 protein processing Any protein maturation process achieved by the cleavage of a peptide bond or bonds within a protein. Protein maturation is the process leading to the attainment of the full functional capacity of a protein.
GO:0044238 primary metabolic process The chemical reactions and pathways involving those compounds which are formed as a part of the normal anabolic and catabolic processes. These processes take place in most, if not all, cells of the organism.
GO:0008150 biological_process Any process specifically pertinent to the functioning of integrated living units: cells, tissues, organs, and organisms. A process is a collection of molecular events with a defined beginning and end.
GO:0043170 macromolecule metabolic process The chemical reactions and pathways involving macromolecules, any molecule of high relative molecular mass, the structure of which essentially comprises the multiple repetition of units derived, actually or conceptually, from molecules of low relative molecular mass.
GO:0010467 gene expression The process in which a gene's sequence is converted into a mature gene product or products (proteins or RNA). This includes the production of an RNA transcript as well as any processing to produce a mature RNA product or an mRNA (for protein-coding genes) and the translation of that mRNA into protein. Protein maturation is included when required to form an active form of a product from an inactive precursor form.
GO:0051604 protein maturation Any process leading to the attainment of the full functional capacity of a protein.
GO:0031638 zymogen activation The proteolytic processing of an inactive enzyme to an active form.
GO:0031639 plasminogen activation The process in which inactive plasminogen is processed to active plasmin. This process includes cleavage at an internal Arg-Val site to form an N-terminal A-chain and C-terminal B-chain held together by a disulfide bond, and can include further proteolytic cleavage events to remove the preactivation peptide.

0 Protein

21 Relations

Relationship
Parent Term . Identifier

Child Term . Identifier
regulates GO:0031639 GO:0010755
positively regulates GO:0031639 GO:0010756
regulates GO:0031639 GO:0010756
negatively regulates GO:0031639 GO:0010757
regulates GO:0031639 GO:0010757
is_a GO:0031638 GO:0031639
part of GO:0071704 GO:0031639
is_a GO:0019538 GO:0031639
is_a GO:0071704 GO:0031639
part of GO:0008152 GO:0031639
is_a GO:0044238 GO:0031639
is_a GO:0043170 GO:0031639
part of GO:0008150 GO:0031639
is_a GO:0051604 GO:0031639
is_a GO:0008152 GO:0031639
is_a GO:0008150 GO:0031639
part of GO:0010467 GO:0031639
is_a GO:0016485 GO:0031639
part of GO:0043170 GO:0031639
is_a GO:0006508 GO:0031639
is_a GO:0031639 GO:0044542

1 Synonyms

Name Type
cleavage of plasminogen to plasmin synonym