GO Term : GO:0008009 chemokine activity GO

Namespace  molecular_function Obsolete  false
description  The function of a family of small chemotactic cytokines; their name is derived from their ability to induce directed chemotaxis in nearby responsive cells. All chemokines possess a number of conserved cysteine residues involved in intramolecular disulfide bond formation. Some chemokines are considered pro-inflammatory and can be induced during an immune response to recruit cells of the immune system to a site of infection, while others are considered homeostatic and are involved in controlling the migration of cells during normal processes of tissue maintenance or development. Chemokines are found in all vertebrates, some viruses and some bacteria.

0 Cross References

1 Ontology

Name
GO

9 Parents

Identifier Name Description
GO:0005515 protein binding Interacting selectively and non-covalently with any protein or protein complex (a complex of two or more proteins that may include other nonprotein molecules).
GO:0005488 binding The selective, non-covalent, often stoichiometric, interaction of a molecule with one or more specific sites on another molecule.
GO:0003674 molecular_function Elemental activities, such as catalysis or binding, describing the actions of a gene product at the molecular level. A given gene product may exhibit one or more molecular functions.
GO:0005102 receptor binding Interacting selectively and non-covalently with one or more specific sites on a receptor molecule, a macromolecule that undergoes combination with a hormone, neurotransmitter, drug or intracellular messenger to initiate a change in cell function.
GO:0005126 cytokine receptor binding Interacting selectively and non-covalently with a cytokine receptor.
GO:0001664 G-protein coupled receptor binding Interacting selectively and non-covalently with a G-protein coupled receptor.
GO:0005125 cytokine activity Functions to control the survival, growth, differentiation and effector function of tissues and cells.
GO:0042379 chemokine receptor binding Interacting selectively and non-covalently with any chemokine receptor.
GO:0008009 chemokine activity The function of a family of small chemotactic cytokines; their name is derived from their ability to induce directed chemotaxis in nearby responsive cells. All chemokines possess a number of conserved cysteine residues involved in intramolecular disulfide bond formation. Some chemokines are considered pro-inflammatory and can be induced during an immune response to recruit cells of the immune system to a site of infection, while others are considered homeostatic and are involved in controlling the migration of cells during normal processes of tissue maintenance or development. Chemokines are found in all vertebrates, some viruses and some bacteria.

0 Protein

8 Relations

Relationship
Parent Term . Identifier

Child Term . Identifier
is_a GO:0005125 GO:0008009
is_a GO:0042379 GO:0008009
is_a GO:0005126 GO:0008009
is_a GO:0001664 GO:0008009
is_a GO:0005102 GO:0008009
is_a GO:0005488 GO:0008009
is_a GO:0005515 GO:0008009
is_a GO:0003674 GO:0008009

0 Synonyms