GO Term : GO:0005070 SH3/SH2 adaptor activity GO

Namespace  molecular_function Obsolete  false
description  Interacting selectively and non-covalently and simultaneously with one or more signal transduction molecules, usually acting as a scaffold to bring these molecules into close proximity either using their own SH2/SH3 domains (e.g. Grb2) or those of their target molecules (e.g. SAM68).

0 Cross References

1 Ontology

Name
GO

7 Parents

Identifier Name Description
GO:0005515 protein binding Interacting selectively and non-covalently with any protein or protein complex (a complex of two or more proteins that may include other nonprotein molecules).
GO:0005488 binding The selective, non-covalent, often stoichiometric, interaction of a molecule with one or more specific sites on another molecule.
GO:0003674 molecular_function Elemental activities, such as catalysis or binding, describing the actions of a gene product at the molecular level. A given gene product may exhibit one or more molecular functions.
GO:0030674 protein binding, bridging The binding activity of a molecule that brings together two or more protein molecules, or a protein and another macromolecule or complex, through a selective, non-covalent, often stoichiometric interaction, permitting those molecules to function in a coordinated way.
GO:0035591 signaling adaptor activity The binding activity of a molecule that brings together two or more molecules in a signaling pathway, permitting those molecules to function in a coordinated way. Adaptor molecules themselves do not have catalytic activity.
GO:0060090 binding, bridging The binding activity of a molecule that brings together two or more molecules through a selective, non-covalent, often stoichiometric interaction, permitting those molecules to function in a coordinated way.
GO:0005070 SH3/SH2 adaptor activity Interacting selectively and non-covalently and simultaneously with one or more signal transduction molecules, usually acting as a scaffold to bring these molecules into close proximity either using their own SH2/SH3 domains (e.g. Grb2) or those of their target molecules (e.g. SAM68).

0 Protein

6 Relations

Relationship
Parent Term . Identifier

Child Term . Identifier
is_a GO:0030674 GO:0005070
is_a GO:0035591 GO:0005070
is_a GO:0005488 GO:0005070
is_a GO:0003674 GO:0005070
is_a GO:0005515 GO:0005070
is_a GO:0060090 GO:0005070

1 Synonyms

Name Type
SH3/SH2 adaptor protein activity synonym