GO Term : GO:0003378 regulation of inflammatory response by sphingosine-1-phosphate signaling pathway GO

Namespace  biological_process Obsolete  false
description  A sphingosine-1-phosphate signaling pathway that modulates the rate, frequency, or extent of the inflammatory response.

0 Cross References

1 Ontology

Name
GO

28 Parents

Identifier Name Description
GO:0007165 signal transduction The cellular process in which a signal is conveyed to trigger a change in the activity or state of a cell. Signal transduction begins with reception of a signal (e.g. a ligand binding to a receptor or receptor activation by a stimulus such as light), or for signal transduction in the absence of ligand, signal-withdrawal or the activity of a constitutively active receptor. Signal transduction ends with regulation of a downstream cellular process, e.g. regulation of transcription or regulation of a metabolic process. Signal transduction covers signaling from receptors located on the surface of the cell and signaling via molecules located within the cell. For signaling between cells, signal transduction is restricted to events at and within the receiving cell.
GO:0006952 defense response Reactions, triggered in response to the presence of a foreign body or the occurrence of an injury, which result in restriction of damage to the organism attacked or prevention/recovery from the infection caused by the attack.
GO:0006950 response to stress Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a disturbance in organismal or cellular homeostasis, usually, but not necessarily, exogenous (e.g. temperature, humidity, ionizing radiation).
GO:0007186 G-protein coupled receptor signaling pathway A series of molecular signals that proceeds with an activated receptor promoting the exchange of GDP for GTP on the alpha-subunit of an associated heterotrimeric G-protein complex. The GTP-bound activated alpha-G-protein then dissociates from the beta- and gamma-subunits to further transmit the signal within the cell. The pathway begins with receptor-ligand interaction, or for basal GPCR signaling the pathway begins with the receptor activating its G protein in the absence of an agonist, and ends with regulation of a downstream cellular process, e.g. transcription. The pathway can start from the plasma membrane, Golgi or nuclear membrane (PMID:24568158 and PMID:16902576).
GO:0031347 regulation of defense response Any process that modulates the frequency, rate or extent of a defense response.
GO:0051716 cellular response to stimulus Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus. The process begins with detection of the stimulus by a cell and ends with a change in state or activity or the cell.
GO:0009611 response to wounding Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus indicating damage to the organism.
GO:0044699 single-organism process A biological process that involves only one organism.
GO:0009987 cellular process Any process that is carried out at the cellular level, but not necessarily restricted to a single cell. For example, cell communication occurs among more than one cell, but occurs at the cellular level.
GO:0008150 biological_process Any process specifically pertinent to the functioning of integrated living units: cells, tissues, organs, and organisms. A process is a collection of molecular events with a defined beginning and end.
GO:0044763 single-organism cellular process Any process that is carried out at the cellular level, occurring within a single organism.
GO:0050896 response to stimulus Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus. The process begins with detection of the stimulus and ends with a change in state or activity or the cell or organism.
GO:0065007 biological regulation Any process that modulates a measurable attribute of any biological process, quality or function.
GO:0050794 regulation of cellular process Any process that modulates the frequency, rate or extent of a cellular process, any of those that are carried out at the cellular level, but are not necessarily restricted to a single cell. For example, cell communication occurs among more than one cell, but occurs at the cellular level.
GO:0050789 regulation of biological process Any process that modulates the frequency, rate or extent of a biological process. Biological processes are regulated by many means; examples include the control of gene expression, protein modification or interaction with a protein or substrate molecule.
GO:0009605 response to external stimulus Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an external stimulus.
GO:0007154 cell communication Any process that mediates interactions between a cell and its surroundings. Encompasses interactions such as signaling or attachment between one cell and another cell, between a cell and an extracellular matrix, or between a cell and any other aspect of its environment.
GO:0044700 single organism signaling A signaling process occurring within a single organism.
GO:0023052 signaling The entirety of a process in which information is transmitted within a biological system. This process begins with an active signal and ends when a cellular response has been triggered.
GO:0080134 regulation of response to stress Any process that modulates the frequency, rate or extent of a response to stress. Response to stress is a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a disturbance in organismal or cellular homeostasis, usually, but not necessarily, exogenous (e.g. temperature, humidity, ionizing radiation).
GO:0048583 regulation of response to stimulus Any process that modulates the frequency, rate or extent of a response to a stimulus. Response to stimulus is a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus.
GO:0006954 inflammatory response The immediate defensive reaction (by vertebrate tissue) to infection or injury caused by chemical or physical agents. The process is characterized by local vasodilation, extravasation of plasma into intercellular spaces and accumulation of white blood cells and macrophages.
GO:0050727 regulation of inflammatory response Any process that modulates the frequency, rate or extent of the inflammatory response, the immediate defensive reaction (by vertebrate tissue) to infection or injury caused by chemical or physical agents.
GO:1903034 regulation of response to wounding Any process that modulates the frequency, rate or extent of response to wounding.
GO:0032101 regulation of response to external stimulus Any process that modulates the frequency, rate or extent of a response to an external stimulus.
GO:0003376 sphingosine-1-phosphate signaling pathway A series of molecular signals initiated by the sphingolipid sphingosine-1-phosphate (S1P) binding to a receptor on the surface of the cell, and which proceeds with the activated receptor transmitting the signal by promoting the exchange of GDP for GTP on the alpha-subunit of an associated heterotrimeric G-protein complex. The pathway ends with regulation of a downstream cellular process, e.g. transcription.
GO:0090520 sphingolipid mediated signaling pathway A series of molecular signals mediated by a sphingolipid.
GO:0003378 regulation of inflammatory response by sphingosine-1-phosphate signaling pathway A sphingosine-1-phosphate signaling pathway that modulates the rate, frequency, or extent of the inflammatory response.

0 Protein

31 Relations

Relationship
Parent Term . Identifier

Child Term . Identifier
is_a GO:0050727 GO:0003378
regulates GO:0006954 GO:0003378
is_a GO:0003376 GO:0003378
regulates GO:0050896 GO:0003378
regulates GO:0008150 GO:0003378
part of GO:0008150 GO:0003378
is_a GO:0007165 GO:0003378
is_a GO:0007186 GO:0003378
part of GO:0007154 GO:0003378
is_a GO:0080134 GO:0003378
is_a GO:0031347 GO:0003378
part of GO:0044763 GO:0003378
part of GO:0050896 GO:0003378
regulates GO:0009605 GO:0003378
is_a GO:0050794 GO:0003378
is_a GO:0048583 GO:0003378
part of GO:0044699 GO:0003378
part of GO:0009987 GO:0003378
is_a GO:0032101 GO:0003378
is_a GO:0008150 GO:0003378
part of GO:0044700 GO:0003378
part of GO:0023052 GO:0003378
regulates GO:0006950 GO:0003378
regulates GO:0009611 GO:0003378
is_a GO:1903034 GO:0003378
is_a GO:0050789 GO:0003378
regulates GO:0009987 GO:0003378
is_a GO:0065007 GO:0003378
part of GO:0051716 GO:0003378
is_a GO:0090520 GO:0003378

2 Synonyms

Name Type
regulation of inflammatory response by sphingolipid signalling pathway synonym
regulation of inflammatory response by sphingolipid signaling pathway synonym