GO Term : GO:0002454 peripheral B cell deletion GO

Namespace  biological_process Obsolete  false
description  The deletion of B cells by apoptotic process occurring as part of peripheral tolerance induction and B cell selection.

0 Cross References

1 Ontology

Name
GO

37 Parents

Identifier Name Description
GO:0007275 multicellular organismal development The biological process whose specific outcome is the progression of a multicellular organism over time from an initial condition (e.g. a zygote or a young adult) to a later condition (e.g. a multicellular animal or an aged adult).
GO:0032502 developmental process A biological process whose specific outcome is the progression of an integrated living unit: an anatomical structure (which may be a subcellular structure, cell, tissue, or organ), or organism over time from an initial condition to a later condition.
GO:0044699 single-organism process A biological process that involves only one organism.
GO:0009987 cellular process Any process that is carried out at the cellular level, but not necessarily restricted to a single cell. For example, cell communication occurs among more than one cell, but occurs at the cellular level.
GO:0008150 biological_process Any process specifically pertinent to the functioning of integrated living units: cells, tissues, organs, and organisms. A process is a collection of molecular events with a defined beginning and end.
GO:0044763 single-organism cellular process Any process that is carried out at the cellular level, occurring within a single organism.
GO:0050896 response to stimulus Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus. The process begins with detection of the stimulus and ends with a change in state or activity or the cell or organism.
GO:0044767 single-organism developmental process A biological process whose specific outcome is the progression of an integrated living unit: an anatomical structure (which may be a subcellular structure, cell, tissue, or organ), or organism over time from an initial condition to a later condition, involving only one organism.
GO:0044707 single-multicellular organism process A biological process occurring within a single, multicellular organism.
GO:0032501 multicellular organismal process Any biological process, occurring at the level of a multicellular organism, pertinent to its function.
GO:0048856 anatomical structure development The biological process whose specific outcome is the progression of an anatomical structure from an initial condition to its mature state. This process begins with the formation of the structure and ends with the mature structure, whatever form that may be including its natural destruction. An anatomical structure is any biological entity that occupies space and is distinguished from its surroundings. Anatomical structures can be macroscopic such as a carpel, or microscopic such as an acrosome.
GO:0048731 system development The process whose specific outcome is the progression of an organismal system over time, from its formation to the mature structure. A system is a regularly interacting or interdependent group of organs or tissues that work together to carry out a given biological process.
GO:0002376 immune system process Any process involved in the development or functioning of the immune system, an organismal system for calibrated responses to potential internal or invasive threats.
GO:0002520 immune system development The process whose specific outcome is the progression of an organismal system whose objective is to provide calibrated responses by an organism to a potential internal or invasive threat, over time, from its formation to the mature structure. A system is a regularly interacting or interdependent group of organs or tissues that work together to carry out a given biological process.
GO:0071887 leukocyte apoptotic process Any apoptotic process in a leukocyte, an achromatic cell of the myeloid or lymphoid lineages capable of ameboid movement, found in blood or other tissue.
GO:0006915 apoptotic process A programmed cell death process which begins when a cell receives an internal (e.g. DNA damage) or external signal (e.g. an extracellular death ligand), and proceeds through a series of biochemical events (signaling pathway phase) which trigger an execution phase. The execution phase is the last step of an apoptotic process, and is typically characterized by rounding-up of the cell, retraction of pseudopodes, reduction of cellular volume (pyknosis), chromatin condensation, nuclear fragmentation (karyorrhexis), plasma membrane blebbing and fragmentation of the cell into apoptotic bodies. When the execution phase is completed, the cell has died.
GO:0008219 cell death Any biological process that results in permanent cessation of all vital functions of a cell. A cell should be considered dead when any one of the following molecular or morphological criteria is met: (1) the cell has lost the integrity of its plasma membrane; (2) the cell, including its nucleus, has undergone complete fragmentation into discrete bodies (frequently referred to as "apoptotic bodies"); and/or (3) its corpse (or its fragments) have been engulfed by an adjacent cell in vivo.
GO:0016265 death A permanent cessation of all vital functions: the end of life; can be applied to a whole organism or to a part of an organism.
GO:0012501 programmed cell death A process which begins when a cell receives an internal or external signal and activates a series of biochemical events (signaling pathway). The process ends with the death of the cell.
GO:0097285 cell-type specific apoptotic process Any apoptotic process in a specific cell type.
GO:0001783 B cell apoptotic process Any apoptotic process in a B cell, a lymphocyte of B lineage with the phenotype CD19-positive and capable of B cell mediated immunity.
GO:0070227 lymphocyte apoptotic process Any apoptotic process in a lymphocyte, a leukocyte commonly found in the blood and lymph that has the characteristics of a large nucleus, a neutral staining cytoplasm, and prominent heterochromatin.
GO:0006955 immune response Any immune system process that functions in the calibrated response of an organism to a potential internal or invasive threat.
GO:0002460 adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains An immune response based on directed amplification of specific receptors for antigen produced through a somatic diversification process that includes somatic recombination of germline gene segments encoding immunoglobulin superfamily domains, and allowing for enhanced responses upon subsequent exposures to the same antigen (immunological memory). Recombined receptors for antigen encoded by immunoglobulin superfamily domains include T cell receptors and immunoglobulins (antibodies). An example of this is the adaptive immune response found in Mus musculus.
GO:0019724 B cell mediated immunity Any process involved with the carrying out of an immune response by a B cell, through, for instance, the production of antibodies or cytokines, or antigen presentation to T cells.
GO:0002449 lymphocyte mediated immunity Any process involved in the carrying out of an immune response by a lymphocyte.
GO:0002443 leukocyte mediated immunity Any process involved in the carrying out of an immune response by a leukocyte.
GO:0002252 immune effector process Any process of the immune system that can potentially contribute to an immune response.
GO:0002250 adaptive immune response An immune response based on directed amplification of specific receptors for antigen produced through a somatic diversification process, and allowing for enhanced response to subsequent exposures to the same antigen (immunological memory).
GO:0002507 tolerance induction A process that directly activates any of the steps required for tolerance, a physiologic state in which the immune system does not react destructively against the components of an organism that harbors it or against antigens that are introduced to it.

0 Protein

43 Relations

Relationship
Parent Term . Identifier

Child Term . Identifier
is_a GO:0002516 GO:0002454
part of GO:0002451 GO:0002454
is_a GO:0044763 GO:0002454
is_a GO:0001783 GO:0002454
is_a GO:1902742 GO:0002454
part of GO:0002507 GO:0002454
is_a GO:0097285 GO:0002454
is_a GO:0008219 GO:0002454
is_a GO:0012501 GO:0002454
part of GO:0002443 GO:0002454
part of GO:0006955 GO:0002454
part of GO:0002520 GO:0002454
part of GO:0048856 GO:0002454
is_a GO:0006915 GO:0002454
part of GO:0002465 GO:0002454
part of GO:0002376 GO:0002454
part of GO:0008150 GO:0002454
is_a GO:0008150 GO:0002454
part of GO:0002449 GO:0002454
is_a GO:0070227 GO:0002454
part of GO:0007275 GO:0002454
part of GO:0032502 GO:0002454
is_a GO:0009987 GO:0002454
is_a GO:0016265 GO:0002454
part of GO:0002514 GO:0002454
is_a GO:0044699 GO:0002454
is_a GO:0071887 GO:0002454
part of GO:0002460 GO:0002454
part of GO:0002461 GO:0002454
part of GO:0048731 GO:0002454

3 Synonyms

Name Type
peripheral B-lymphocyte deletion synonym
peripheral B lymphocyte deletion synonym
peripheral B-cell deletion synonym