GO Term : GO:0002342 central B cell deletion GO

Namespace  biological_process Obsolete  false
description  The deletion of B cells by apoptotic process occurring as part of central tolerance induction and B cell selection.

0 Cross References

1 Ontology

Name
GO

42 Parents

Identifier Name Description
GO:0007275 multicellular organismal development The biological process whose specific outcome is the progression of a multicellular organism over time from an initial condition (e.g. a zygote or a young adult) to a later condition (e.g. a multicellular animal or an aged adult).
GO:0032502 developmental process A biological process whose specific outcome is the progression of an integrated living unit: an anatomical structure (which may be a subcellular structure, cell, tissue, or organ), or organism over time from an initial condition to a later condition.
GO:0030154 cell differentiation The process in which relatively unspecialized cells, e.g. embryonic or regenerative cells, acquire specialized structural and/or functional features that characterize the cells, tissues, or organs of the mature organism or some other relatively stable phase of the organism's life history. Differentiation includes the processes involved in commitment of a cell to a specific fate and its subsequent development to the mature state.
GO:0048513 organ development Development of a tissue or tissues that work together to perform a specific function or functions. Development pertains to the process whose specific outcome is the progression of a structure over time, from its formation to the mature structure. Organs are commonly observed as visibly distinct structures, but may also exist as loosely associated clusters of cells that work together to perform a specific function or functions.
GO:0044699 single-organism process A biological process that involves only one organism.
GO:0009987 cellular process Any process that is carried out at the cellular level, but not necessarily restricted to a single cell. For example, cell communication occurs among more than one cell, but occurs at the cellular level.
GO:0008150 biological_process Any process specifically pertinent to the functioning of integrated living units: cells, tissues, organs, and organisms. A process is a collection of molecular events with a defined beginning and end.
GO:0044763 single-organism cellular process Any process that is carried out at the cellular level, occurring within a single organism.
GO:0044767 single-organism developmental process A biological process whose specific outcome is the progression of an integrated living unit: an anatomical structure (which may be a subcellular structure, cell, tissue, or organ), or organism over time from an initial condition to a later condition, involving only one organism.
GO:0044707 single-multicellular organism process A biological process occurring within a single, multicellular organism.
GO:0032501 multicellular organismal process Any biological process, occurring at the level of a multicellular organism, pertinent to its function.
GO:0048856 anatomical structure development The biological process whose specific outcome is the progression of an anatomical structure from an initial condition to its mature state. This process begins with the formation of the structure and ends with the mature structure, whatever form that may be including its natural destruction. An anatomical structure is any biological entity that occupies space and is distinguished from its surroundings. Anatomical structures can be macroscopic such as a carpel, or microscopic such as an acrosome.
GO:0048869 cellular developmental process A biological process whose specific outcome is the progression of a cell over time from an initial condition to a later condition.
GO:0048731 system development The process whose specific outcome is the progression of an organismal system over time, from its formation to the mature structure. A system is a regularly interacting or interdependent group of organs or tissues that work together to carry out a given biological process.
GO:0046649 lymphocyte activation A change in morphology and behavior of a lymphocyte resulting from exposure to a specific antigen, mitogen, cytokine, chemokine, cellular ligand, or soluble factor.
GO:0002376 immune system process Any process involved in the development or functioning of the immune system, an organismal system for calibrated responses to potential internal or invasive threats.
GO:0001775 cell activation A change in the morphology or behavior of a cell resulting from exposure to an activating factor such as a cellular or soluble ligand.
GO:0045321 leukocyte activation A change in morphology and behavior of a leukocyte resulting from exposure to a specific antigen, mitogen, cytokine, cellular ligand, or soluble factor.
GO:0042113 B cell activation The change in morphology and behavior of a mature or immature B cell resulting from exposure to a mitogen, cytokine, chemokine, cellular ligand, or an antigen for which it is specific.
GO:0030098 lymphocyte differentiation The process in which a relatively unspecialized precursor cell acquires specialized features of a lymphocyte. A lymphocyte is a leukocyte commonly found in the blood and lymph that has the characteristics of a large nucleus, a neutral staining cytoplasm, and prominent heterochromatin.
GO:0030097 hemopoiesis The process whose specific outcome is the progression of the myeloid and lymphoid derived organ/tissue systems of the blood and other parts of the body over time, from formation to the mature structure. The site of hemopoiesis is variable during development, but occurs primarily in bone marrow or kidney in many adult vertebrates.
GO:0048534 hematopoietic or lymphoid organ development The process whose specific outcome is the progression of any organ involved in hematopoiesis (also known as hemopoiesis) or lymphoid cell activation over time, from its formation to the mature structure. Such development includes differentiation of resident cell types (stromal cells) and of migratory cell types dependent on the unique microenvironment afforded by the organ for their proper differentiation.
GO:0002521 leukocyte differentiation The process in which a relatively unspecialized hemopoietic precursor cell acquires the specialized features of a leukocyte. A leukocyte is an achromatic cell of the myeloid or lymphoid lineages capable of ameboid movement, found in blood or other tissue.
GO:0002520 immune system development The process whose specific outcome is the progression of an organismal system whose objective is to provide calibrated responses by an organism to a potential internal or invasive threat, over time, from its formation to the mature structure. A system is a regularly interacting or interdependent group of organs or tissues that work together to carry out a given biological process.
GO:0071887 leukocyte apoptotic process Any apoptotic process in a leukocyte, an achromatic cell of the myeloid or lymphoid lineages capable of ameboid movement, found in blood or other tissue.
GO:0006915 apoptotic process A programmed cell death process which begins when a cell receives an internal (e.g. DNA damage) or external signal (e.g. an extracellular death ligand), and proceeds through a series of biochemical events (signaling pathway phase) which trigger an execution phase. The execution phase is the last step of an apoptotic process, and is typically characterized by rounding-up of the cell, retraction of pseudopodes, reduction of cellular volume (pyknosis), chromatin condensation, nuclear fragmentation (karyorrhexis), plasma membrane blebbing and fragmentation of the cell into apoptotic bodies. When the execution phase is completed, the cell has died.
GO:0008219 cell death Any biological process that results in permanent cessation of all vital functions of a cell. A cell should be considered dead when any one of the following molecular or morphological criteria is met: (1) the cell has lost the integrity of its plasma membrane; (2) the cell, including its nucleus, has undergone complete fragmentation into discrete bodies (frequently referred to as "apoptotic bodies"); and/or (3) its corpse (or its fragments) have been engulfed by an adjacent cell in vivo.
GO:0016265 death A permanent cessation of all vital functions: the end of life; can be applied to a whole organism or to a part of an organism.
GO:0012501 programmed cell death A process which begins when a cell receives an internal or external signal and activates a series of biochemical events (signaling pathway). The process ends with the death of the cell.
GO:0097285 cell-type specific apoptotic process Any apoptotic process in a specific cell type.

0 Protein

50 Relations

Relationship
Parent Term . Identifier

Child Term . Identifier
part of GO:0002510 GO:0002342
is_a GO:0002516 GO:0002342
part of GO:0002340 GO:0002342
is_a GO:0070227 GO:0002342
is_a GO:0071887 GO:0002342
is_a GO:0006915 GO:0002342
is_a GO:1902742 GO:0002342
part of GO:0048513 GO:0002342
is_a GO:0016265 GO:0002342
part of GO:0002339 GO:0002342
part of GO:0044707 GO:0002342
is_a GO:0009987 GO:0002342
part of GO:0048534 GO:0002342
part of GO:0044763 GO:0002342
part of GO:0002376 GO:0002342
part of GO:0002520 GO:0002342
part of GO:0001775 GO:0002342
part of GO:0044767 GO:0002342
part of GO:0030183 GO:0002342
part of GO:0030098 GO:0002342
part of GO:0002514 GO:0002342
is_a GO:0044699 GO:0002342
part of GO:0048856 GO:0002342
is_a GO:0008150 GO:0002342
part of GO:0044699 GO:0002342
part of GO:0030154 GO:0002342
part of GO:0008150 GO:0002342
part of GO:0002508 GO:0002342
part of GO:0002507 GO:0002342
is_a GO:0001783 GO:0002342

3 Synonyms

Name Type
central B lymphocyte deletion synonym
central B-cell deletion synonym
central B-lymphocyte deletion synonym