GO Term : GO:0001913 T cell mediated cytotoxicity GO

Namespace  biological_process Obsolete  false
description  The directed killing of a target cell by a T cell through the release of granules containing cytotoxic mediators or through the engagement of death receptors.

0 Cross References

1 Ontology

Name
GO

14 Parents

Identifier Name Description
GO:0044699 single-organism process A biological process that involves only one organism.
GO:0008150 biological_process Any process specifically pertinent to the functioning of integrated living units: cells, tissues, organs, and organisms. A process is a collection of molecular events with a defined beginning and end.
GO:0050896 response to stimulus Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus. The process begins with detection of the stimulus and ends with a change in state or activity or the cell or organism.
GO:0002376 immune system process Any process involved in the development or functioning of the immune system, an organismal system for calibrated responses to potential internal or invasive threats.
GO:0001909 leukocyte mediated cytotoxicity The directed killing of a target cell by a leukocyte.
GO:0006955 immune response Any immune system process that functions in the calibrated response of an organism to a potential internal or invasive threat.
GO:0002460 adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains An immune response based on directed amplification of specific receptors for antigen produced through a somatic diversification process that includes somatic recombination of germline gene segments encoding immunoglobulin superfamily domains, and allowing for enhanced responses upon subsequent exposures to the same antigen (immunological memory). Recombined receptors for antigen encoded by immunoglobulin superfamily domains include T cell receptors and immunoglobulins (antibodies). An example of this is the adaptive immune response found in Mus musculus.
GO:0002449 lymphocyte mediated immunity Any process involved in the carrying out of an immune response by a lymphocyte.
GO:0002443 leukocyte mediated immunity Any process involved in the carrying out of an immune response by a leukocyte.
GO:0001906 cell killing Any process in an organism that results in the killing of its own cells or those of another organism, including in some cases the death of the other organism. Killing here refers to the induction of death in one cell by another cell, not cell-autonomous death due to internal or other environmental conditions.
GO:0002252 immune effector process Any process of the immune system that can potentially contribute to an immune response.
GO:0002250 adaptive immune response An immune response based on directed amplification of specific receptors for antigen produced through a somatic diversification process, and allowing for enhanced response to subsequent exposures to the same antigen (immunological memory).
GO:0002456 T cell mediated immunity Any process involved in the carrying out of an immune response by a T cell.
GO:0001913 T cell mediated cytotoxicity The directed killing of a target cell by a T cell through the release of granules containing cytotoxic mediators or through the engagement of death receptors.

0 Protein

32 Relations

Relationship
Parent Term . Identifier

Child Term . Identifier
is_a GO:0044699 GO:0001913
is_a GO:0001909 GO:0001913
is_a GO:0002456 GO:0001913
is_a GO:0002250 GO:0001913
is_a GO:0002449 GO:0001913
is_a GO:0002252 GO:0001913
is_a GO:0001906 GO:0001913
is_a GO:0006955 GO:0001913
is_a GO:0002460 GO:0001913
is_a GO:0008150 GO:0001913
is_a GO:0050896 GO:0001913
is_a GO:0002443 GO:0001913
is_a GO:0002376 GO:0001913
regulates GO:0001913 GO:0001914
negatively regulates GO:0001913 GO:0001915
regulates GO:0001913 GO:0001915
positively regulates GO:0001913 GO:0001916
regulates GO:0001913 GO:0001916
is_a GO:0001913 GO:0002419
regulates GO:0001913 GO:0002852
negatively regulates GO:0001913 GO:0002853
regulates GO:0001913 GO:0002853
positively regulates GO:0001913 GO:0002854
regulates GO:0001913 GO:0002854
part of GO:0001913 GO:0043316
regulates GO:0001913 GO:0043317
regulates GO:0001913 GO:0043318
negatively regulates GO:0001913 GO:0043318
regulates GO:0001913 GO:0043319
positively regulates GO:0001913 GO:0043319

10 Synonyms

Name Type
T-lymphocyte mediated cytotoxicity synonym
T-cell mediated cytotoxicity synonym
T-cell mediated cell killing synonym
T-cell mediated cell death synonym
T-cell mediated apoptosis synonym
T cell mediated cytolysis synonym
T lymphocyte mediated cytotoxicity synonym
T cell mediated cell death synonym
T cell mediated cell killing synonym
T cell mediated apoptosis synonym