GO Term : GO:0001771 immunological synapse formation GO

Namespace  biological_process Obsolete  false
description  The formation of an area of close contact between a lymphocyte (T-, B-, or natural killer cell) and a target cell through the clustering of particular signaling and adhesion molecules and their associated membrane rafts on both the lymphocyte and target cell, which facilitates activation of the lymphocyte, transfer of membrane from the target cell to the lymphocyte, and in some situations killing of the target cell through release of secretory granules and/or death-pathway ligand-receptor interaction.

0 Cross References

1 Ontology

Name
GO

11 Parents

Identifier Name Description
GO:0044699 single-organism process A biological process that involves only one organism.
GO:0009987 cellular process Any process that is carried out at the cellular level, but not necessarily restricted to a single cell. For example, cell communication occurs among more than one cell, but occurs at the cellular level.
GO:0008150 biological_process Any process specifically pertinent to the functioning of integrated living units: cells, tissues, organs, and organisms. A process is a collection of molecular events with a defined beginning and end.
GO:0044763 single-organism cellular process Any process that is carried out at the cellular level, occurring within a single organism.
GO:0046649 lymphocyte activation A change in morphology and behavior of a lymphocyte resulting from exposure to a specific antigen, mitogen, cytokine, chemokine, cellular ligand, or soluble factor.
GO:0002376 immune system process Any process involved in the development or functioning of the immune system, an organismal system for calibrated responses to potential internal or invasive threats.
GO:0001775 cell activation A change in the morphology or behavior of a cell resulting from exposure to an activating factor such as a cellular or soluble ligand.
GO:0045321 leukocyte activation A change in morphology and behavior of a leukocyte resulting from exposure to a specific antigen, mitogen, cytokine, cellular ligand, or soluble factor.
GO:0001771 immunological synapse formation The formation of an area of close contact between a lymphocyte (T-, B-, or natural killer cell) and a target cell through the clustering of particular signaling and adhesion molecules and their associated membrane rafts on both the lymphocyte and target cell, which facilitates activation of the lymphocyte, transfer of membrane from the target cell to the lymphocyte, and in some situations killing of the target cell through release of secretory granules and/or death-pathway ligand-receptor interaction.
GO:0009988 cell-cell recognition Cell recognition between cells. May involve the formation of specialized cell junctions.
GO:0008037 cell recognition The process in which a cell in an organism interprets its surroundings.

0 Protein

20 Relations

Relationship
Parent Term . Identifier

Child Term . Identifier
is_a GO:0009988 GO:0001771
part of GO:0046649 GO:0001771
part of GO:0044699 GO:0001771
part of GO:0001775 GO:0001771
part of GO:0008150 GO:0001771
part of GO:0009987 GO:0001771
is_a GO:0008037 GO:0001771
is_a GO:0008150 GO:0001771
part of GO:0045321 GO:0001771
part of GO:0044763 GO:0001771
is_a GO:0044699 GO:0001771
part of GO:0002376 GO:0001771
is_a GO:0044763 GO:0001771
is_a GO:0009987 GO:0001771
regulates GO:0001771 GO:2000520
negatively regulates GO:0001771 GO:2000521
regulates GO:0001771 GO:2000521
positively regulates GO:0001771 GO:2000522
regulates GO:0001771 GO:2000522
part of GO:0001771 GO:2000526

1 Synonyms

Name Type
formation of immunological synapse synonym