Blast Analysis : gnl|CDD|162077

Analysis  rpsblast_cdd Start  49
End  231 Strand  +
Length  183 Note  Gaps:15
Hit Coverage  82.76 Hit Length  232
Hit Pident  26.56 E Val  4e-10
Hit Description  TIGR00869 sec62 protein translocation protein Sec62 family. Members of the NSCC2 family have been sequenced from various yeast fungal and animals species including Saccharomyces cerevisiae Drosophila melanogaster and Homo sapiens. These proteins are the Sec62 proteins believed to be associated with the Sec61 and Sec63 constituents of the general protein secretary systems of yeast microsomes. They are also the non-selective cation (NS) channels of the mammalian cytoplasmic membrane. The yeast Sec62 protein has been shown to be essential for cell growth. The mammalian NS channel proteins has been implicated in platelet derived growth factor(PGDF) dependent single channel current in fibroblasts. These channels are essentially closed in serum deprived tissue-culture cells and are specifically opened by exposure to PDGF. These channels are reported to exhibit equal selectivity for Na+ K+ and Cs+ with low permeability to Ca2+ and no permeability to anions. Hit Pcons  18.75
Name  Qrob_P0663920.2

1 Protein

Protein Identifier
Organism . Name
Score Score Type Protein Description Alias (in v1) Code Enzyme Gene Prediction Quality
Qrob_P0663920.2 Quercus robur 100.0 egn (M=1) K12275 - translocation protein SEC62     validated