| Analysis | rpsblast_cdd | Start | 427 |
| End | 586 | Strand | + |
| Length | 160 | Note | Gaps:23 |
| Hit Coverage | 100.00 | Hit Length | 181 |
| Hit Pident | 54.14 | E Val | 2e-61 |
| Hit Description | pfam11916 Vac14_Fig4_bd Vacuolar protein 14 C-terminal Fig4p binding. Vac14 is a scaffold for the Fab1 kinase complex a complex that allows for the dynamic interconversion of PI3P and PI(3 5)P2p (phosphoinositide phosphate (PIP) lipids that are generated transiently on the cytoplasmic face of selected intracellular membranes). This interconversion is regulated by at least five proteins in yeast: the lipid kinase Fab1p lipid phosphatase Fig4p the Fab1p activator Vac7p the Fab1p inhibitor Atg18p and Vac14p a protein required for the activity of both Fab1p and Fig4p. The C-terminal region of Vac14 binds to Fig4p. The full length Vac14 in yeasts is likely to be a protein carrying a succession of HEAT repeats most of which have now degenerated. This regulatory system is crucial for the proper functioning of the mammalian nervous system. | Hit Pcons | 14.92 |
| Name | Qrob_P0600570.2 |
| Protein Identifier |
Organism . Name |
Score | Score Type | Protein Description | Alias (in v1) | Code Enzyme | Gene Prediction Quality |
|---|---|---|---|---|---|---|---|
| Qrob_P0600570.2 | Quercus robur | 100.0 | egn | (M=1) K15305 - vacuole morphology and inheritance protein 14 | validated |
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