Blast Analysis : gnl|CDD|176646

Analysis  rpsblast_cdd Start  1149
End  1257 Strand  +
Length  109 Note  Gaps:5
Hit Coverage  52.26 Hit Length  199
Hit Pident  35.58 E Val  3e-08
Hit Description  cd05160 DEDDy_DNA_polB_exo DEDDy 3'-5' exonuclease domain of family-B DNA polymerases. The 3'-5' exonuclease domain of family-B DNA polymerases. This domain has a fundamental role in reducing polymerase errors and is involved in proofreading activity. Family-B DNA polymerases contain an N-terminal DEDDy DnaQ-like exonuclease domain in the same polypeptide chain as the polymerase domain similar to family-A DNA polymerases. This domain contains three sequence motifs termed ExoI ExoII and ExoIII with a specific YX(3)D pattern at ExoIII. These motifs are clustered around the active site and contain four conserved acidic residues that serve as ligands for the two metal ions required for catalysis. The exonuclease domain of family B polymerase also contains a beta hairpin structure that plays an important role in active site switching in the event of nucleotide misincorporation. Members include Escherichia coli DNA polymerase II some eubacterial phage DNA polymerases nuclear replicative DNA polymerases (alpha delta epsilon and zeta) and eukaryotic viral and plasmid-borne enzymes. Nuclear DNA polymerases alpha and zeta lack the four conserved acidic metal-binding residues. Family-B DNA polymerases are predominantly involved in DNA replication and DNA repair. Hit Pcons  15.38
Name  Qrob_P0591810.2
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1 Protein

Protein Identifier
Organism . Name 		Score Score Type Protein Description Alias (in v1) Code Enzyme Gene Prediction Quality
Qrob_P0591810.2 Quercus robur 0.0 egn (M=1) KOG0968//KOG0969 - DNA polymerase zeta catalytic subunit [Replication recombination and repair]. // DNA polymerase delta catalytic subunit [Replication recombination and repair].   EC:2.7.7.7 validated