| Analysis | rpsblast_cdd | Start | 178 |
| End | 250 | Strand | + |
| Length | 73 | Note | Gaps:1 |
| Hit Coverage | 98.67 | Hit Length | 75 |
| Hit Pident | 29.73 | E Val | 3e-08 |
| Hit Description | cd03418 GRX_GRXb_1_3_like Glutaredoxin (GRX) family GRX bacterial class 1 and 3 (b_1_3)-like subfamily composed of bacterial GRXs approximately 10 kDa in size and proteins containing a GRX or GRX-like domain. GRX is a glutathione (GSH) dependent reductase catalyzing the disulfide reduction of target proteins such as ribonucleotide reductase. It contains a redox active CXXC motif in a TRX fold and uses a similar dithiol mechanism employed by TRXs for intramolecular disulfide bond reduction of protein substrates. Unlike TRX GRX has preference for mixed GSH disulfide substrates in which it uses a monothiol mechanism where only the N-terminal cysteine is required. The flow of reducing equivalents in the GRX system goes from NADPH -> GSH reductase -> GSH -> GRX -> protein substrates. By altering the redox state of target proteins GRX is involved in many cellular functions including DNA synthesis signal transduction and the defense against oxidative stress. Different classes are known including E. coli GRX1 and GRX3 which are members of this subfamily.. | Hit Pcons | 21.62 |
| Name | Qrob_P0500140.2 |
| Protein Identifier |
Organism . Name |
Score | Score Type | Protein Description | Alias (in v1) | Code Enzyme | Gene Prediction Quality |
|---|---|---|---|---|---|---|---|
| Qrob_P0500140.2 | Quercus robur | (M=1) PF00610 - Domain found in Dishevelled, Egl-10, and Pleckstrin (DEP) | Qrob_P0939260.1 | manual_v1 |
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