Blast Analysis : gnl|CDD|28920

Analysis	rpsblast_cdd	Start	251
End	372	Strand	+
Length	122	Note	Gaps:16
Hit Coverage	92.17	Hit Length	115
Hit Pident	22.64	E Val	8e-07
Hit Description	cd00038 CAP_ED effector domain of the CAP family of transcription factors members include CAP (or cAMP receptor protein (CRP)) which binds cAMP FNR (fumarate and nitrate reduction) which uses an iron-sulfur cluster to sense oxygen) and CooA a heme containing CO sensor. In all cases binding of the effector leads to conformational changes and the ability to activate transcription. Cyclic nucleotide-binding domain similar to CAP are also present in cAMP- and cGMP-dependent protein kinases (cAPK and cGPK) and vertebrate cyclic nucleotide-gated ion-channels. Cyclic nucleotide-monophosphate binding domain proteins that bind cyclic nucleotides (cAMP or cGMP) share a structural domain of about 120 residues the best studied is the prokaryotic catabolite gene activator CAP where such a domain is known to be composed of three alpha-helices and a distinctive eight-stranded antiparallel beta-barrel structure three conserved glycine residues are thought to be essential for maintenance of the structural integrity of the beta-barrel CooA is a homodimeric transcription factor that belongs to CAP family cAMP- and cGMP-dependent protein kinases (cAPK and cGPK) contain two tandem copies of the cyclic nucleotide-binding domain cAPK's are composed of two different subunits a catalytic chain and a regulatory chain which contains both copies of the domain cGPK's are single chain enzymes that include the two copies of the domain in their N-terminal section also found in vertebrate cyclic nucleotide-gated ion-channels.	Hit Pcons	16.98
Name	Qrob_P0429820.2

1 Protein

Protein Identifier	Organism . Name	Score	Score Type	Protein Description	Alias (in v1)	Code Enzyme	Gene Prediction Quality
Qrob_P0429820.2	Quercus robur	99.3	egn	(M=34) K05391 - cyclic nucleotide gated channel, other eukaryote			validated

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