Blast Analysis : gnl|CDD|117723

Analysis  rpsblast_cdd Start  509
End  576 Strand  +
Length  68 Note  none
Hit Coverage  34.87 Hit Length  195
Hit Pident  42.65 E Val  4e-13
Hit Description  pfam09169 BRCA-2_helical BRCA2 helical. Members of this family adopt a helical structure consisting of a four-helix cluster core (alpha 1 alpha 8 alpha 9 alpha 10) and two successive beta-hairpins (beta 1 to beta 4). An approx. 50-amino acid segment that contains four short helices (alpha 2 to alpha 4) meanders around the surface of the core structure. In BRCA2 the alpha 9 and alpha 10 helices pack with BRCA-2_OB1 (pfam09103) through van der Waals contacts involving hydrophobic and aromatic residues and also through side-chain and backbone hydrogen bonds. The domain binds the 70-amino acid DSS1 (deleted in split-hand/split foot syndrome) protein which was originally identified as one of three genes that map to a 1.5-Mb locus deleted in an inherited developmental malformation syndrome. Hit Pcons  16.18
Name  Qrob_P0383020.2

1 Protein

Protein Identifier
Organism . Name
Score Score Type Protein Description Alias (in v1) Code Enzyme Gene Prediction Quality
Qrob_P0383020.2 Quercus robur 96.1 egn (M=1) K08775 - breast cancer 2 susceptibility protein     validated