| Analysis | rpsblast_cdd | Start | 21 |
| End | 397 | Strand | + |
| Length | 377 | Note | Gaps:47 |
| Hit Coverage | 100.00 | Hit Length | 390 |
| Hit Pident | 50.00 | E Val | 1e-138 |
| Hit Description | cd07322 PriL_PriS_Eukaryotic Eukaryotic core primase: Large subunit PriL. Primases synthesize the RNA primers required for DNA replication. Primases are grouped into two classes bacteria/bacteriophage and archaeal/eukaryotic. The proteins in the two classes differ in structure and the replication apparatus components. Archaeal/eukaryotic core primase is a heterodimeric enzyme consisting of a small catalytic subunit (PriS) and a large subunit (PriL). In eukaryotic organisms a heterotetrameric enzyme formed by DNA polymerase alpha the B subunit and two primase subunits has primase activity. Although the catalytic activity resides within PriS the PriL subunit is essential for primase function as disruption of the PriL gene in yeast is lethal. PriL is composed of two structural domains. Several functions have been proposed for PriL such as stabilization of the PriS involvement in synthesis initiation improvement of primase processivity determination of product size and transfer of the products to DNA polymerase alpha. | Hit Pcons | 17.18 |
| Name | Qrob_P0343710.2 |
| Protein Identifier |
Organism . Name |
Score | Score Type | Protein Description | Alias (in v1) | Code Enzyme | Gene Prediction Quality |
|---|---|---|---|---|---|---|---|
| Qrob_P0343710.2 | Quercus robur | 97.1 | egn | (M=1) K02685 - DNA primase large subunit [EC:2.7.7.-] | validated |
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