Blast Analysis : gnl|CDD|153137

Analysis  rpsblast_cdd Start  43
End  302 Strand  +
Length  260 Note  Gaps:26
Hit Coverage  85.23 Hit Length  298
Hit Pident  25.20 E Val  6e-28
Hit Description  cd06269 PBP1_glutamate_receptors_like Family C G-protein couples receptors (GPCRs) membrane bound guanylyl cyclases such as the family of natriuretic peptide receptors (NPRs) and the N-terminal leucine/isoleucine/valine- binding protein (LIVBP)-like domain of the ionotropic glutamate receptors. This CD represents the ligand-binding domain of the family C G-protein couples receptors (GPCRs) membrane bound guanylyl cyclases such as the family of natriuretic peptide receptors (NPRs) and the N-terminal leucine/isoleucine/valine- binding protein (LIVBP)-like domain of the ionotropic glutamate receptors all of which are structurally similar and related to the periplasmic-binding fold type I family. The family C GPCRs consist of metabotropic glutamate receptor (mGluR) receptors a calcium-sensing receptor (CaSR) gamma-aminobutyric receptors (GABAb) the promiscuous L-alpha-amino acid receptor GPR6A families of taste and pheromone receptors and orphan receptors. Truncated splicing variants of the orphan receptors are not included in this CD. The family C GPCRs are activated by endogenous agonists such as amino acids ions and sugar based molecules. Their amino terminal ligand-binding region is homologous to the bacterial leucine-isoleucine-valine binding protein (LIVBP) and a leucine binding protein (LBP). The ionotropic glutamate receptors (iGluRs) have an integral ion channel and are subdivided into three major groups based on their pharmacology and structural similarities: NMDA receptors AMPA receptors and kainate receptors. The family of membrane bound guanylyl cyclases is further divided into three subfamilies: the ANP receptor (GC-A)/C-type natriuretic peptide receptor (GC-B) the heat-stable enterotoxin receptor (GC-C)/sensory organ specific membrane GCs such as retinal receptors (GC-E GC-F) and olfactory receptors (GC-D and GC-G). Hit Pcons  20.47
Name  Qrob_P0311250.2
Paste the following link
Lists
This BlastAnalysis isn't in any lists. Upload a list.

1 Protein

Protein Identifier
Organism . Name 		Score Score Type Protein Description Alias (in v1) Code Enzyme Gene Prediction Quality
Qrob_P0311250.2 Quercus robur 3.1 egn (M=11) KOG1052//KOG1053//KOG1054//KOG1055//KOG1056//KOG4440 - Glutamate-gated kainate-type ion channel receptor subunit GluR5 and related subunits [Inorganic ion transport and metabolism Amino acid transport and metabolism Signal transduction mechanisms]. // Glutamate-gated NMDA-type ion channel receptor subunit GRIN2A and related subunits [Inorganic ion transport and metabolism Amino acid transport and metabolism Signal transduction mechanisms]. // Glutamate-gated AMPA-type ion channel receptor subunit GluR2 and related subunits [Inorganic ion transport and metabolism Amino acid transport and metabolism Signal transduction mechanisms]. // GABA-B ion channel receptor subunit GABABR1 and related subunits G-protein coupled receptor superfamily [Inorganic ion transport and metabolism Amino acid transport and metabolism Signal transduction mechanisms]. // Glutamate-gated metabotropic ion channel receptor subunit GRM2 and related subunits G-protein coupled receptor superfamily [Inorganic ion transport and metabolism Signal transduction mechanisms]. // NMDA selective glutamate-gated ion channel receptor subunit GRIN1 [Inorganic ion transport and metabolism Amino acid transport and metabolism Signal transduction mechanisms].     validated