Blast Analysis : gnl|CDD|30093

Analysis	rpsblast_cdd	Start	99
End	164	Strand	+
Length	66	Note	Gaps:1
Hit Coverage	20.12	Hit Length	333
Hit Pident	34.33	E Val	5e-07
Hit Description	cd01371 KISc_KIF3 Kinesin motor domain kinesins II or KIF3_like proteins. Subgroup of kinesins which form heterotrimers composed of 2 kinesins and one non-motor accessory subunit. Kinesins II play important roles in ciliary transport and have been implicated in neuronal transport melanosome transport the secretory pathway and mitosis. This catalytic (head) domain has ATPase activity and belongs to the larger group of P-loop NTPases. Kinesins are microtubule-dependent molecular motors that play important roles in intracellular transport and in cell division. In this group the motor domain is found at the N-terminus (N-type). N-type kinesins are (+) end-directed motors i.e. they transport cargo towards the (+) end of the microtubule. Kinesin motor domains hydrolyze ATP at a rate of about 80 per second and move along the microtubule at a speed of about 6400 Angstroms per second. To achieve that kinesin head groups work in pairs. Upon replacing ADP with ATP a kinesin motor domain increases its affinity for microtubule binding and locks in place. Also the neck linker binds to the motor domain which repositions the other head domain through the coiled-coil domain close to a second tubulin dimer about 80 Angstroms along the microtubule. Meanwhile ATP hydrolysis takes place and when the second head domain binds to the microtubule the first domain again replaces ADP with ATP triggering a conformational change that pulls the first domain forward..	Hit Pcons	25.37
Name	Qrob_P0292080.2

1 Protein

Protein Identifier	Organism . Name	Score	Score Type	Protein Description	Alias (in v1)	Code Enzyme	Gene Prediction Quality
Qrob_P0292080.2	Quercus robur	81.6	egn	(M=1) KOG0242//KOG4280 - Kinesin-like protein [Cytoskeleton]. // Kinesin-like protein [Cytoskeleton].		EC:3.6.4.4	validated

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