| Analysis | rpsblast_cdd | Start | 22 |
| End | 274 | Strand | + |
| Length | 253 | Note | Gaps:10 |
| Hit Coverage | 93.21 | Hit Length | 280 |
| Hit Pident | 31.80 | E Val | 3e-32 |
| Hit Description | cd08062 MPN_RPN7_8 Mpr1p Pad1p N-terminal (MPN) domains without catalytic isopeptidase activity found in 19S proteasomal subunits Rpn7 and Rpn8. This family includes lid subunits of the 26 S proteasome regulatory particles Rpn7 (PSMD7 proteasome 26S non-ATPase subunit 7 p44) and Rpn8 (PSMD8 proteasome 26S non-ATPase subunit 8 p40 Mov34). Rpn7 is known to be critical for the integrity of the 26 S proteasome complex by establishing a correct lid structure. It is necessary for the incorporation/anchoring of Rpn3 and Rpn12 to the lid and essential for viability and normal mitosis. Rpn7 and Rpn8 are ATP-independent components of the 19S regulator subunit and contain the MPN structural motif on its N-terminal region. However while they show a typical MPN metalloprotease fold they lack the canonical JAMM motif and therefore do not show catalytic isopeptidase activity. It is suggested that Rpn7 function is primarily structural. | Hit Pcons | 18.77 |
| Name | Qrob_P0236660.2 |
| Protein Identifier |
Organism . Name |
Score | Score Type | Protein Description | Alias (in v1) | Code Enzyme | Gene Prediction Quality |
|---|---|---|---|---|---|---|---|
| Qrob_P0236660.2 | Quercus robur | 100.0 | egn | (M=1) K03249 - translation initiation factor eIF-3 subunit 5 | validated |
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