| Analysis | rpsblast_cdd | Start | 14 |
| End | 172 | Strand | + |
| Length | 159 | Note | Gaps:25 |
| Hit Coverage | 94.87 | Hit Length | 156 |
| Hit Pident | 31.08 | E Val | 1e-10 |
| Hit Description | cd06130 DNA_pol_III_epsilon_like an uncharacterized bacterial subgroup of the DEDDh 3'-5' exonuclease domain family with similarity to the epsilon subunit of DNA polymerase III. This subfamily is composed of uncharacterized bacterial proteins with similarity to the epsilon subunit of DNA polymerase III (Pol III) a multisubunit polymerase which is the main DNA replicating enzyme in bacteria functioning as the chromosomal replicase. The Pol III holoenzyme is a complex of ten different subunits three of which (alpha epsilon and theta) compose the catalytic core. The Pol III epsilon subunit encoded by the dnaQ gene is a DEDDh-type 3'-5' exonuclease which is responsible for the proofreading activity of the polymerase increasing the fidelity of DNA synthesis. It contains three conserved sequence motifs termed ExoI ExoII and ExoIII with a specific Hx(4)D conserved pattern at ExoIII. These motifs are clustered around the active site and contain four conserved acidic residues that serve as ligands for the two metal ions required for catalysis. The epsilon subunit of Pol III also functions as a stabilizer of the holoenzyme complex. | Hit Pcons | 17.57 |
| Name | Qrob_P0183300.2 |
| Protein Identifier |
Organism . Name |
Score | Score Type | Protein Description | Alias (in v1) | Code Enzyme | Gene Prediction Quality |
|---|---|---|---|---|---|---|---|
| Qrob_P0183300.2 | Quercus robur | 100.0 | egn | (M=3) PTHR30231 - DNA POLYMERASE III SUBUNIT EPSILON | EC:2.7.7.7 | validated |
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