| Analysis | rpsblast_cdd | Start | 1 |
| End | 225 | Strand | + |
| Length | 225 | Note | Gaps:65 |
| Hit Coverage | 94.64 | Hit Length | 224 |
| Hit Pident | 41.51 | E Val | 9e-45 |
| Hit Description | cd01851 GBP Guanylate-binding protein (GBP) family (N-terminal domain). Guanylate-binding protein (GBP) N-terminal domain. Guanylate-binding proteins (GBPs) define a group of proteins that are synthesized after activation of the cell by interferons. The biochemical properties of GBPs are clearly different from those of Ras-like and heterotrimeric GTP-binding proteins. They bind guanine nucleotides with low affinity (micromolar range) are stable in their absence and have a high turnover GTPase. In addition to binding GDP/GTP they have the unique ability to bind GMP with equal affinity and hydrolyze GTP not only to GDP but also to GMP. Furthermore two unique regions around the base and the phosphate-binding areas the guanine and the phosphate caps respectively give the nucleotide-binding site a unique appearance not found in the canonical GTP-binding proteins. The phosphate cap which constitutes the region analogous to switch I completely shields the phosphate-binding site from solvent such that a potential GTPase-activating protein (GAP) cannot approach. | Hit Pcons | 12.74 |
| Name | Qrob_P0085910.2 |
| Protein Identifier |
Organism . Name |
Score | Score Type | Protein Description | Alias (in v1) | Code Enzyme | Gene Prediction Quality |
|---|---|---|---|---|---|---|---|
| Qrob_P0085910.2 | Quercus robur | 69.2 | egn | (M=2) PTHR11649:SF62 - PROTEIN SEY1 HOMOLOG (PTHR11649:SF62) | validated |
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