Blast Analysis : gnl|CDD|187690

Analysis  rpsblast_cdd Start  401
End  524 Strand  +
Length  124 Note  Gaps:1
Hit Coverage  100.00 Hit Length  123
Hit Pident  39.84 E Val  1e-26
Hit Description  cd06222 RNase_H RNase H is an endonuclease that cleaves the RNA strand of an RNA/DNA hybrid in a sequence non-specific manner. Ribonuclease H (RNase H) enzymes are divided into two major families Type 1 and Type 2 based on amino acid sequence similarities and biochemical properties. RNase H is an endonuclease that cleaves the RNA strand of an RNA/DNA hybrid in a sequence non-specific manner in the presence of divalent cations. RNase H is widely present in various organisms including bacteria archaea and eukaryotes. Most prokaryotic and eukaryotic genomes contain multiple RNase H genes. Despite the lack of amino acid sequence homology Type 1 and type 2 RNase H share a main-chain fold and steric configurations of the four acidic active-site residues and have the same catalytic mechanism and functions in cells. RNase H is involved in DNA replication repair and transcription. One of the important functions of RNase H is to remove Okazaki fragments during DNA replication. RNase H inhibitors have been explored as an anti-HIV drug target because RNase H inactivation inhibits reverse transcription. Hit Pcons  17.89
Name  Qrob_P0035690.2
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1 Protein

Protein Identifier
Organism . Name 		Score Score Type Protein Description Alias (in v1) Code Enzyme Gene Prediction Quality
Qrob_P0035690.2 Quercus robur 21.1 egn (M=1) PF00078//PF13456//PF13966 - Reverse transcriptase (RNA-dependent DNA polymerase) // Reverse transcriptase-like // zinc-binding in reverse transcriptase   EC:2.7.7.49 validated