| Analysis | rpsblast_cdd | Start | 53 |
| End | 361 | Strand | + |
| Length | 309 | Note | Gaps:28 |
| Hit Coverage | 100.00 | Hit Length | 120 |
| Hit Pident | 57.50 | E Val | 1e-32 |
| Hit Description | cd04048 C2A_Copine C2 domain first repeat in Copine. There are 2 copies of the C2 domain present in copine a protein involved in membrane trafficking protein-protein interactions and perhaps even cell division and growth. C2 domains fold into an 8-standed beta-sandwich that can adopt 2 structural arrangements: Type I and Type II distinguished by a circular permutation involving their N- and C-terminal beta strands. Many C2 domains are Ca2+-dependent membrane-targeting modules that bind a wide variety of substances including bind phospholipids inositol polyphosphates and intracellular proteins. Most C2 domain proteins are either signal transduction enzymes that contain a single C2 domain such as protein kinase C or membrane trafficking proteins which contain at least two C2 domains such as synaptotagmin 1. However there are a few exceptions to this including RIM isoforms and some splice variants of piccolo/aczonin and intersectin which only have a single C2 domain. C2 domains with a calcium binding region have negatively charged residues primarily aspartates that serve as ligands for calcium ions. This cd contains the first C2 repeat C2A and has a type-I topology. | Hit Pcons | 14.17 |
| Name | Qrob_P0027210.2 |
| Protein Identifier |
Organism . Name |
Score | Score Type | Protein Description | Alias (in v1) | Code Enzyme | Gene Prediction Quality |
|---|---|---|---|---|---|---|---|
| Qrob_P0027210.2 | Quercus robur | 93.0 | egn | (M=8) PTHR10857//PTHR10857:SF24 - COPINE // SUBFAMILY NOT NAMED | validated |
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