| Analysis | rpsblast_cdd | Start | 2016 |
| End | 2315 | Strand | + |
| Length | 300 | Note | none |
| Hit Coverage | 100.00 | Hit Length | 222 |
| Hit Pident | 51.35 | E Val | 1e-37 |
| Hit Description | cd05164 PIKKc Phosphoinositide 3-kinase-related protein kinase (PIKK) subfamily catalytic domain The PIKK catalytic domain subfamily is part of a larger superfamily that includes the catalytic domains of other kinases such as the typical serine/threonine/tyrosine protein kinases (PKs) aminoglycoside phosphotransferase choline kinase and RIO kinases. Members include ATM (Ataxia telangiectasia mutated) ATR (Ataxia telangiectasia and Rad3-related) TOR (Target of rapamycin) SMG-1 (Suppressor of morphogenetic effect on genitalia-1) and DNA-PK (DNA-dependent protein kinase). PIKKs have intrinsic serine/threonine kinase activity and are distinguished from other PKs by their unique catalytic domain similar to that of lipid PI3K and their large molecular weight (240-470 kDa). They show strong preference for phosphorylating serine/threonine residues followed by a glutamine and are also referred to as (S/T)-Q-directed kinases. They all contain a FATC (FRAP ATM and TRRAP C-terminal) domain. PIKKs have diverse functions including cell-cycle checkpoints genome surveillance mRNA surveillance and translation control.. | Hit Pcons | 17.57 |
| Name | Qrob_P0010570.2 |
| Protein Identifier |
Organism . Name |
Score | Score Type | Protein Description | Alias (in v1) | Code Enzyme | Gene Prediction Quality |
|---|---|---|---|---|---|---|---|
| Qrob_P0010570.2 | Quercus robur | 100.0 | egn | (M=1) K08873 - PI-3-kinase-related kinase SMG-1 | EC:2.7.11.1 | validated |
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