Blast Analysis : gnl|CDD|119424

Analysis  rpsblast_cdd Start  403
End  671 Strand  +
Length  269 Note  Gaps:49
Hit Coverage  99.10 Hit Length  222
Hit Pident  49.55 E Val  1e-71
Hit Description  cd05164 PIKKc Phosphoinositide 3-kinase-related protein kinase (PIKK) subfamily catalytic domain The PIKK catalytic domain subfamily is part of a larger superfamily that includes the catalytic domains of other kinases such as the typical serine/threonine/tyrosine protein kinases (PKs) aminoglycoside phosphotransferase choline kinase and RIO kinases. Members include ATM (Ataxia telangiectasia mutated) ATR (Ataxia telangiectasia and Rad3-related) TOR (Target of rapamycin) SMG-1 (Suppressor of morphogenetic effect on genitalia-1) and DNA-PK (DNA-dependent protein kinase). PIKKs have intrinsic serine/threonine kinase activity and are distinguished from other PKs by their unique catalytic domain similar to that of lipid PI3K and their large molecular weight (240-470 kDa). They show strong preference for phosphorylating serine/threonine residues followed by a glutamine and are also referred to as (S/T)-Q-directed kinases. They all contain a FATC (FRAP ATM and TRRAP C-terminal) domain. PIKKs have diverse functions including cell-cycle checkpoints genome surveillance mRNA surveillance and translation control.. Hit Pcons  17.27
Name  Qrob_P0005700.2
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1 Protein

Protein Identifier
Organism . Name 		Score Score Type Protein Description Alias (in v1) Code Enzyme Gene Prediction Quality
Qrob_P0005700.2 Quercus robur 18.0 egn (M=1) KOG0889//KOG0890//KOG0891//KOG0892//KOG0903//KOG0904//KOG0905//KOG0906 - Histone acetyltransferase SAGA TRRAP/TRA1 component PI-3 kinase superfamily [Signal transduction mechanisms Chromatin structure and dynamics Replication recombination and repair Cell cycle control cell division chromosome partitioning]. // Protein kinase of the PI-3 kinase family involved in mitotic growth DNA repair and meiotic recombination [Signal transduction mechanisms Chromatin structure and dynamics Replication recombination and repair Cell cycle control cell division chromosome partitioning]. // DNA-dependent protein kinase [Replication recombination and repair]. // Protein kinase ATM/Tel1 involved in telomere length regulation and DNA repair [Signal transduction mechanisms Chromatin structure and dynamics Replication recombination and repair Cell cycle control cell division chromosome partitioning]. // Phosphatidylinositol 4-kinase involved in intracellular trafficking and secretion [Signal transduction mechanisms Intracellular trafficking secretion and vesicular transport]. // Phosphatidylinositol 3-kinase catalytic subunit (p110) [Signal transduction mechanisms]. // Phosphoinositide 3-kinase [Signal transduction mechanisms]. // Phosphatidylinositol 3-kinase VPS34 involved in signal transduction [Signal transduction mechanisms Intracellular trafficking secretion and vesicular transport].   EC:2.7.11.1 validated