Protein : Qrob_P0736360.2 Q. robur
Protein Identifier  ? Qrob_P0736360.2 Organism . Name  Quercus robur
Score  100.0 Score Type  egn
Protein Description  (M=1) KOG0253//KOG0254//KOG0255//KOG0569//KOG1330//KOG2532 - Synaptic vesicle transporter SV2 (major facilitator superfamily) [General function prediction only]. // Predicted transporter (major facilitator superfamily) [General function prediction only]. // Synaptic vesicle transporter SVOP and related transporters (major facilitator superfamily) [General function prediction only]. // Permease of the major facilitator superfamily [Carbohydrate transport and metabolism]. // Sugar transporter/spinster transmembrane protein [Carbohydrate transport and metabolism]. // Permease of the major facilitator superfamily [Carbohydrate transport and metabolism]. Gene Prediction Quality  validated
Protein length 

Sequence

Length: 422  
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0 Synonyms

6 GO Terms

Identifier Name Description
GO:0016020 membrane A lipid bilayer along with all the proteins and protein complexes embedded in it an attached to it.
GO:0055085 transmembrane transport The process in which a solute is transported from one side of a membrane to the other.
GO:0016021 integral component of membrane The component of a membrane consisting of the gene products and protein complexes having at least some part of their peptide sequence embedded in the hydrophobic region of the membrane.
GO:0022857 transmembrane transporter activity Enables the transfer of a substance from one side of a membrane to the other.
GO:0022891 substrate-specific transmembrane transporter activity Enables the transfer of a specific substance or group of related substances from one side of a membrane to the other.
GO:0005215 transporter activity Enables the directed movement of substances (such as macromolecules, small molecules, ions) into, out of or within a cell, or between cells.

36 Blast

Analysis Hit Start End Strand Length Note Hit Coverage Hit Length Hit Pident E Val Hit Description
blastp_kegg lcl|tcc:TCM_025451 1 413 + 413 Gaps:1 82.24 501 85.92 0.0 Major facilitator superfamily protein
blastp_kegg lcl|pmum:103333505 1 413 + 413 Gaps:2 82.20 500 84.91 0.0 D-xylose-proton symporter-like 2
blastp_kegg lcl|pper:PRUPE_ppa004602mg 1 413 + 413 Gaps:2 82.20 500 84.67 0.0 hypothetical protein
blastp_kegg lcl|pxb:103943298 1 413 + 413 Gaps:1 82.24 501 85.19 0.0 D-xylose-proton symporter-like 2
blastp_kegg lcl|cic:CICLE_v10019791mg 1 413 + 413 Gaps:4 92.46 451 84.17 0.0 hypothetical protein
blastp_kegg lcl|pxb:103951509 1 413 + 413 Gaps:1 82.24 501 84.95 0.0 D-xylose-proton symporter-like 2
blastp_kegg lcl|cit:102610785 1 413 + 413 Gaps:4 82.41 506 84.17 0.0 D-xylose-proton symporter-like 2-like
blastp_kegg lcl|mdm:103426510 1 413 + 413 Gaps:1 82.24 501 83.98 0.0 D-xylose-proton symporter-like 2
blastp_kegg lcl|mdm:103440015 1 413 + 413 Gaps:1 82.24 501 84.47 0.0 D-xylose-proton symporter-like 2
blastp_kegg lcl|pop:POPTR_0019s08330g 1 381 + 381 none 85.43 446 87.66 0.0 POPTRDRAFT_1108211 hypothetical protein
blastp_uniprot_sprot sp|Q6AWX0|XYLL2_ARATH 1 413 + 413 Gaps:3 82.31 503 76.09 0.0 D-xylose-proton symporter-like 2 OS Arabidopsis thaliana GN At5g17010 PE 1 SV 1
blastp_uniprot_sprot sp|Q8L6Z8|XYLL1_ARATH 1 413 + 413 Gaps:3 82.31 503 70.05 0.0 D-xylose-proton symporter-like 1 OS Arabidopsis thaliana GN At3g03090 PE 2 SV 1
blastp_uniprot_sprot sp|Q0WWW9|XYLL3_ARATH 18 413 + 396 Gaps:3 71.51 558 61.40 5e-164 D-xylose-proton symporter-like 3 chloroplastic OS Arabidopsis thaliana GN At5g59250 PE 1 SV 2
blastp_uniprot_sprot sp|C0SPB2|YWTG_BACSU 50 398 + 349 Gaps:27 70.90 457 36.73 7e-52 Putative metabolite transport protein YwtG OS Bacillus subtilis (strain 168) GN ywtG PE 3 SV 1
blastp_uniprot_sprot sp|Q9BE72|GTR12_MACFA 54 388 + 335 Gaps:24 50.72 621 37.14 1e-46 Solute carrier family 2 facilitated glucose transporter member 12 OS Macaca fascicularis GN SLC2A12 PE 2 SV 1
blastp_uniprot_sprot sp|O34718|IOLT_BACSU 51 409 + 359 Gaps:26 72.94 473 33.91 4e-46 Major myo-inositol transporter IolT OS Bacillus subtilis (strain 168) GN iolT PE 2 SV 1
blastp_uniprot_sprot sp|Q8TD20|GTR12_HUMAN 54 388 + 335 Gaps:24 51.05 617 36.51 5e-46 Solute carrier family 2 facilitated glucose transporter member 12 OS Homo sapiens GN SLC2A12 PE 2 SV 1
blastp_uniprot_sprot sp|P30605|ITR1_YEAST 4 394 + 391 Gaps:44 67.64 584 31.39 3e-45 Myo-inositol transporter 1 OS Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN ITR1 PE 1 SV 2
blastp_uniprot_sprot sp|Q8VZ80|PLT5_ARATH 14 413 + 400 Gaps:27 74.77 539 28.78 6e-45 Polyol transporter 5 OS Arabidopsis thaliana GN PLT5 PE 1 SV 2
blastp_uniprot_sprot sp|Q94CI6|EDL18_ARATH 25 412 + 388 Gaps:37 77.20 478 35.23 4e-44 Sugar transporter ERD6-like 18 OS Arabidopsis thaliana GN SFP2 PE 2 SV 1
rpsblast_cdd gnl|CDD|200987 51 412 + 362 Gaps:27 79.96 449 35.65 4e-53 pfam00083 Sugar_tr Sugar (and other) transporter.
rpsblast_cdd gnl|CDD|162084 51 412 + 362 Gaps:26 76.09 481 32.79 8e-47 TIGR00879 SP MFS transporter sugar porter (SP) family. This model represent the sugar porter subfamily of the major facilitator superfamily (pfam00083).
rpsblast_cdd gnl|CDD|182225 51 409 + 359 Gaps:43 75.16 479 32.78 9e-44 PRK10077 xylE D-xylose transporter XylE Provisional.
rpsblast_cdd gnl|CDD|162097 93 404 + 312 Gaps:33 57.62 505 28.18 2e-17 TIGR00898 2A0119 cation transport protein.
rpsblast_cdd gnl|CDD|162095 47 392 + 346 Gaps:54 84.92 398 22.78 2e-16 TIGR00895 2A0115 benzoate transport.
rpsblast_cdd gnl|CDD|119392 42 231 + 190 Gaps:10 100.00 352 32.95 8e-16 cd06174 MFS The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters symporters and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of substrates including ions sugar phosphates drugs neurotransmitters nucleosides amino acids and peptides. They do so using the electrochemical potential of the transported substrates. Uniporters transport a single substrate while symporters and antiporters transport two substrates in the same or in opposite directions respectively across membranes. MFS proteins are typically 400 to 600 amino acids in length and the majority contain 12 transmembrane alpha helices (TMs) connected by hydrophilic loops. The N- and C-terminal halves of these proteins display weak similarity and may be the result of a gene duplication/fusion event. Based on kinetic studies and the structures of a few bacterial superfamily members GlpT (glycerol-3-phosphate transporter) LacY (lactose permease) and EmrD (multidrug transporter) MFS proteins are thought to function through a single substrate binding site alternating-access mechanism involving a rocker-switch type of movement. Bacterial members function primarily for nutrient uptake and as drug-efflux pumps to confer antibiotic resistance. Some MFS proteins have medical significance in humans such as the glucose transporter Glut4 which is impaired in type II diabetes and glucose-6-phosphate transporter (G6PT) which causes glycogen storage disease when mutated..
rpsblast_cdd gnl|CDD|191813 85 230 + 146 Gaps:1 41.91 346 31.03 2e-12 pfam07690 MFS_1 Major Facilitator Superfamily.
rpsblast_cdd gnl|CDD|183191 85 237 + 153 Gaps:10 37.68 406 32.03 2e-10 PRK11551 PRK11551 putative 3-hydroxyphenylpropionic transporter MhpT Provisional.
rpsblast_cdd gnl|CDD|32643 88 230 + 143 Gaps:1 36.04 394 29.58 2e-10 COG2814 AraJ Arabinose efflux permease [Carbohydrate transport and metabolism].
rpsblast_cdd gnl|CDD|162092 85 236 + 152 Gaps:17 37.78 405 24.18 4e-08 TIGR00891 2A0112 putative sialic acid transporter.

37 Domain Motifs

Analysis Begin End Length Domain Identifier Cross Ref Description Inter Pro
PRINTS 57 67 11 PR00171 "Reactome:REACT_15518" Sugar transporter signature IPR003663
PRINTS 147 166 20 PR00171 "Reactome:REACT_15518" Sugar transporter signature IPR003663
PRINTS 315 325 11 PR00171 "Reactome:REACT_15518" Sugar transporter signature IPR003663
Gene3D 311 410 100 G3DSA:1.20.1250.20 none none none
Phobius 1 40 40 NON_CYTOPLASMIC_DOMAIN none Region of a membrane-bound protein predicted to be outside the membrane, in the extracellular region. none
Phobius 397 415 19 TRANSMEMBRANE none Region of a membrane-bound protein predicted to be embedded in the membrane. none
PANTHER 4 413 410 PTHR24063 none none none
Phobius 41 62 22 TRANSMEMBRANE none Region of a membrane-bound protein predicted to be embedded in the membrane. none
ProSiteProfiles 49 421 373 PS50850 none Major facilitator superfamily (MFS) profile. IPR020846
Phobius 365 370 6 CYTOPLASMIC_DOMAIN none Region of a membrane-bound protein predicted to be outside the membrane, in the cytoplasm. none
Phobius 371 391 21 TRANSMEMBRANE none Region of a membrane-bound protein predicted to be embedded in the membrane. none
Phobius 304 327 24 TRANSMEMBRANE none Region of a membrane-bound protein predicted to be embedded in the membrane. none
Pfam 51 413 363 PF00083 none Sugar (and other) transporter IPR005828
ProSitePatterns 110 127 18 PS00216 none Sugar transport proteins signature 1. IPR005829
ProSitePatterns 360 376 17 PS00216 none Sugar transport proteins signature 1. IPR005829
Phobius 347 364 18 TRANSMEMBRANE none Region of a membrane-bound protein predicted to be embedded in the membrane. none
Phobius 170 180 11 CYTOPLASMIC_DOMAIN none Region of a membrane-bound protein predicted to be outside the membrane, in the cytoplasm. none
Phobius 392 396 5 NON_CYTOPLASMIC_DOMAIN none Region of a membrane-bound protein predicted to be outside the membrane, in the extracellular region. none
ProSitePatterns 152 177 26 PS00217 none Sugar transport proteins signature 2. IPR005829
Phobius 92 111 20 TRANSMEMBRANE none Region of a membrane-bound protein predicted to be embedded in the membrane. none
Phobius 328 346 19 NON_CYTOPLASMIC_DOMAIN none Region of a membrane-bound protein predicted to be outside the membrane, in the extracellular region. none
Phobius 123 141 19 TRANSMEMBRANE none Region of a membrane-bound protein predicted to be embedded in the membrane. none
Phobius 142 146 5 NON_CYTOPLASMIC_DOMAIN none Region of a membrane-bound protein predicted to be outside the membrane, in the extracellular region. none
Phobius 112 122 11 CYTOPLASMIC_DOMAIN none Region of a membrane-bound protein predicted to be outside the membrane, in the cytoplasm. none
Gene3D 85 236 152 G3DSA:1.20.1250.20 none none none
PANTHER 4 413 410 PTHR24063:SF320 none none none
Phobius 63 68 6 CYTOPLASMIC_DOMAIN none Region of a membrane-bound protein predicted to be outside the membrane, in the cytoplasm. none
Phobius 416 421 6 CYTOPLASMIC_DOMAIN none Region of a membrane-bound protein predicted to be outside the membrane, in the cytoplasm. none
Phobius 181 199 19 TRANSMEMBRANE none Region of a membrane-bound protein predicted to be embedded in the membrane. none
Phobius 211 230 20 TRANSMEMBRANE none Region of a membrane-bound protein predicted to be embedded in the membrane. none

10 Localization

Analysis Start End Length
TMHMM 397 416 19
TMHMM 342 364 22
TMHMM 92 114 22
TMHMM 217 239 22
TMHMM 146 168 22
TMHMM 40 62 22
TMHMM 305 327 22
TMHMM 180 202 22
TMHMM 371 393 22
TMHMM 123 141 18

0 Qtllist

0 Targeting