Protein : Qrob_P0699430.2 Q. robur

Protein Identifier  ? Qrob_P0699430.2 Organism . Name  Quercus robur
Score  100.0 Score Type  egn
Protein Description  (M=2) PTHR11122:SF10 - APOSPORY-ASSOCIATED PROTEIN C-RELATED (PTHR11122:SF10) Code Enzyme  EC:5.1.3.15
Gene Prediction Quality  validated Protein length 

Sequence

Length: 305  
Kegg Orthology  K01792

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0 Synonyms

4 GO Terms

Identifier Name Description
GO:0003824 catalytic activity Catalysis of a biochemical reaction at physiological temperatures. In biologically catalyzed reactions, the reactants are known as substrates, and the catalysts are naturally occurring macromolecular substances known as enzymes. Enzymes possess specific binding sites for substrates, and are usually composed wholly or largely of protein, but RNA that has catalytic activity (ribozyme) is often also regarded as enzymatic.
GO:0005975 carbohydrate metabolic process The chemical reactions and pathways involving carbohydrates, any of a group of organic compounds based of the general formula Cx(H2O)y. Includes the formation of carbohydrate derivatives by the addition of a carbohydrate residue to another molecule.
GO:0030246 carbohydrate binding Interacting selectively and non-covalently with any carbohydrate, which includes monosaccharides, oligosaccharides and polysaccharides as well as substances derived from monosaccharides by reduction of the carbonyl group (alditols), by oxidation of one or more hydroxy groups to afford the corresponding aldehydes, ketones, or carboxylic acids, or by replacement of one or more hydroxy group(s) by a hydrogen atom. Cyclitols are generally not regarded as carbohydrates.
GO:0016853 isomerase activity Catalysis of the geometric or structural changes within one molecule. Isomerase is the systematic name for any enzyme of EC class 5.

31 Blast

Analysis Hit Start End Strand Length Note Hit Coverage Hit Length Hit Pident E Val Hit Description
blastp_kegg lcl|cic:CICLE_v10021324mg 1 304 + 304 none 100.00 304 81.58 0.0 hypothetical protein
blastp_kegg lcl|rcu:RCOM_1690740 1 304 + 304 Gaps:1 100.00 305 80.66 0.0 aldose 1-epimerase putative
blastp_kegg lcl|cit:102624498 1 304 + 304 none 100.00 304 81.25 0.0 putative glucose-6-phosphate 1-epimerase-like
blastp_kegg lcl|pper:PRUPE_ppa009170mg 1 304 + 304 Gaps:1 100.00 303 82.51 0.0 hypothetical protein
blastp_kegg lcl|tcc:TCM_016391 1 304 + 304 none 100.00 304 81.58 0.0 Galactose mutarotase-like superfamily protein
blastp_kegg lcl|cam:101510208 1 304 + 304 Gaps:2 100.00 304 84.21 0.0 putative glucose-6-phosphate 1-epimerase-like
blastp_kegg lcl|pmum:103337689 1 304 + 304 Gaps:1 100.00 303 81.85 0.0 putative glucose-6-phosphate 1-epimerase
blastp_kegg lcl|mtr:MTR_5g009670 1 304 + 304 Gaps:2 100.00 304 84.21 0.0 Apospory-associated protein C
blastp_kegg lcl|vvi:100243178 1 304 + 304 none 97.44 312 79.93 0.0 putative glucose-6-phosphate 1-epimerase-like
blastp_kegg lcl|sly:101265664 1 304 + 304 Gaps:1 100.00 303 79.54 0.0 putative glucose-6-phosphate 1-epimerase-like
blastp_pdb 2cis_A 25 294 + 270 Gaps:32 92.26 297 33.94 1e-36 mol:protein length:297 GLUCOSE-6-PHOSPHATE 1-EPIMERASE
blastp_pdb 2cir_A 25 294 + 270 Gaps:32 92.26 297 33.94 1e-36 mol:protein length:297 HEXOSE-6-PHOSPHATE MUTAROTASE
blastp_pdb 2ciq_A 25 294 + 270 Gaps:32 92.26 297 33.94 1e-36 mol:protein length:297 HEXOSE-6-PHOSPHATE MUTAROTASE
blastp_pdb 2htb_D 26 283 + 258 Gaps:16 79.61 309 32.11 2e-30 mol:protein length:309 Putative enzyme related to aldose 1-epimerase
blastp_pdb 2htb_C 26 283 + 258 Gaps:16 79.61 309 32.11 2e-30 mol:protein length:309 Putative enzyme related to aldose 1-epimerase
blastp_pdb 2htb_B 26 283 + 258 Gaps:16 79.61 309 32.11 2e-30 mol:protein length:309 Putative enzyme related to aldose 1-epimerase
blastp_pdb 2htb_A 26 283 + 258 Gaps:16 79.61 309 32.11 2e-30 mol:protein length:309 Putative enzyme related to aldose 1-epimerase
blastp_pdb 2hta_B 26 283 + 258 Gaps:16 79.61 309 32.11 2e-30 mol:protein length:309 Putative enzyme related to aldose 1-epimerase
blastp_pdb 2hta_A 26 283 + 258 Gaps:16 79.61 309 32.11 2e-30 mol:protein length:309 Putative enzyme related to aldose 1-epimerase
blastp_pdb 1jov_A 19 281 + 263 Gaps:42 87.78 270 29.54 5e-20 mol:protein length:270 HI1317
blastp_uniprot_sprot sp|Q40784|AAPC_CENCI 14 304 + 291 Gaps:3 88.75 329 64.38 3e-139 Putative glucose-6-phosphate 1-epimerase OS Cenchrus ciliaris PE 2 SV 1
blastp_uniprot_sprot sp|Q03161|YMY9_YEAST 25 294 + 270 Gaps:32 92.26 297 33.94 5e-36 Glucose-6-phosphate 1-epimerase OS Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN YMR099C PE 1 SV 1
blastp_uniprot_sprot sp|P39173|YEAD_ECOLI 26 278 + 253 Gaps:16 81.97 294 33.20 1e-31 Putative glucose-6-phosphate 1-epimerase OS Escherichia coli (strain K12) GN yeaD PE 1 SV 2
blastp_uniprot_sprot sp|P44160|Y1317_HAEIN 54 281 + 228 Gaps:40 74.54 271 29.21 4e-14 Putative glucose-6-phosphate 1-epimerase OS Haemophilus influenzae (strain ATCC 51907 / DSM 11121 / KW20 / Rd) GN HI_1317 PE 3 SV 1
rpsblast_cdd gnl|CDD|185697 26 299 + 274 Gaps:12 99.63 269 44.40 2e-89 cd09020 D-hex-6-P-epi_like D-hexose-6-phosphate epimerase-like. D-Hexose-6-phosphate epimerase Ymr099c from Saccharomyces cerevisiae belongs to the large superfamily of aldose-1-epimerases. Its active site is very similar to the catalytic site of galactose mutarotase the best studied member of the superfamily. It also contains the conserved glutamate and histidine residues that have been shown in galactose mutarotase to be critical for catalysis the glutamate serving as the active site base to initiate the reaction by removing the proton from the C-1 hydroxyl group of the sugar substrate and the histidine as the active site acid to protonate the C-5 ring oxygen. In addition Ymr099c contains 2 conserved arginine residues which are involved in phosphate binding and exhibits hexose-6-phosphate mutarotase activity on glucose-6-P galactose-6-P and mannose-6-P.
rpsblast_cdd gnl|CDD|201693 25 299 + 275 Gaps:47 99.67 301 25.33 5e-52 pfam01263 Aldose_epim Aldose 1-epimerase.
rpsblast_cdd gnl|CDD|31020 21 302 + 282 Gaps:21 92.33 287 35.47 2e-49 COG0676 COG0676 Uncharacterized enzymes related to aldose 1-epimerase [Carbohydrate transport and metabolism].
rpsblast_cdd gnl|CDD|185702 34 251 + 218 Gaps:31 80.81 271 28.31 1e-20 cd09025 Aldose_epim_Slr1438 Aldose 1-epimerase similar to Synechocystis Slr1438. Proteins similar to Synechocystis Slr1438 are uncharacterized members of aldose-1-epimerase superfamily. Aldose 1-epimerases or mutarotases are key enzymes of carbohydrate metabolism catalyzing the interconversion of the alpha- and beta-anomers of hexose sugars such as glucose and galactose. This interconversion is an important step that allows anomer specific metabolic conversion of sugars. Studies of the catalytic mechanism of the best known member of the family galactose mutarotase have shown a glutamate and a histidine residue to be critical for catalysis the glutamate serves as the active site base to initiate the reaction by removing the proton from the C-1 hydroxyl group of the sugar substrate and the histidine as the active site acid to protonate the C-5 ring oxygen.
rpsblast_cdd gnl|CDD|185695 36 253 + 218 Gaps:44 84.51 284 17.08 1e-09 cd01081 Aldose_epim aldose 1-epimerase superfamily. Aldose 1-epimerases or mutarotases are key enzymes of carbohydrate metabolism they catalyze the interconversion of the alpha- and beta-anomers of hexose sugars such as glucose and galactose. This interconversion is an important step that allows anomer specific metabolic conversion of sugars. Studies of the catalytic mechanism of the best known member of the family galactose mutarotase have shown a glutamate and a histidine residue to be critical for catalysis the glutamate serves as the active site base to initiate the reaction by removing the proton from the C-1 hydroxyl group of the sugar substrate and the histidine as the active site acid to protonate the C-5 ring oxygen.
rpsblast_cdd gnl|CDD|185701 35 300 + 266 Gaps:90 97.22 288 21.79 4e-07 cd09024 Aldose_epim_lacX Aldose 1-epimerase similar to Lactococcus lactis lacX. Proteins similar to Lactococcus lactis lacX are uncharacterized members of aldose-1-epimerase superfamily. Aldose 1-epimerases or mutarotases are key enzymes of carbohydrate metabolism catalyzing the interconversion of the alpha- and beta-anomers of hexose sugars such as glucose and galactose. This interconversion is an important step that allows anomer specific metabolic conversion of sugars. Studies of the catalytic mechanism of the best known member of the family galactose mutarotase have shown a glutamate and a histidine residue to be critical for catalysis the glutamate serves as the active site base to initiate the reaction by removing the proton from the C-1 hydroxyl group of the sugar substrate and the histidine as the active site acid to protonate the C-5 ring oxygen.

6 Domain Motifs

Analysis Begin End Length Domain Identifier Cross Ref Description Inter Pro
Gene3D 7 300 294 G3DSA:2.70.98.10 none none IPR014718
Pfam 25 298 274 PF01263 none Aldose 1-epimerase IPR008183
PANTHER 9 304 296 PTHR11122:SF10 none none none
PIRSF 1 303 303 PIRSF016020 "KEGG:00010+5.1.3.15","MetaCyc:PWY-2723","MetaCyc:PWY-5384","MetaCyc:PWY-5940","MetaCyc:PWY-621","MetaCyc:PWY-622","MetaCyc:PWY-6731","MetaCyc:PWY-6737","MetaCyc:PWY-6981","MetaCyc:PWY-7238","MetaCyc:PWY-7343" none IPR025532
PANTHER 9 304 296 PTHR11122 none none none
SUPERFAMILY 19 298 280 SSF74650 none none IPR011013

0 Localization

0 Qtllist

0 Targeting