Protein : Qrob_P0694560.2 Q. robur
Protein Identifier  ? Qrob_P0694560.2 Organism . Name  Quercus robur
Score  100.0 Score Type  egn
Protein Description  (M=2) K04499 - RuvB-like protein 1 (pontin 52) Code Enzyme  EC:3.6.4.12
Gene Prediction Quality  validated Protein length 

Sequence

Length: 439  
Kegg Orthology  K04499
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0 Synonyms

3 GO Terms

Identifier Name Description
GO:0005524 ATP binding Interacting selectively and non-covalently with ATP, adenosine 5'-triphosphate, a universally important coenzyme and enzyme regulator.
GO:0003678 DNA helicase activity Catalysis of the reaction: NTP + H2O = NDP + phosphate, to drive the unwinding of a DNA helix.
GO:0043141 ATP-dependent 5'-3' DNA helicase activity Catalysis of the reaction: ATP + H2O = ADP + phosphate; drives the unwinding of the DNA helix in the direction 5' to 3'.

33 Blast

Analysis Hit Start End Strand Length Note Hit Coverage Hit Length Hit Pident E Val Hit Description
blastp_kegg lcl|gmx:100809596 1 438 + 438 Gaps:20 100.00 458 88.65 0.0 ruvB-like protein 1-like
blastp_kegg lcl|gmx:102659805 1 438 + 438 Gaps:20 100.00 458 88.65 0.0 ruvB-like protein 1-like
blastp_kegg lcl|pxb:103966378 1 438 + 438 Gaps:20 100.00 458 88.65 0.0 ruvB-like protein 1
blastp_kegg lcl|vvi:100262179 4 438 + 435 Gaps:20 100.00 455 88.57 0.0 ruvB-like 1-like
blastp_kegg lcl|pvu:PHAVU_010G148200g 1 438 + 438 Gaps:20 100.00 458 88.21 0.0 hypothetical protein
blastp_kegg lcl|pmum:103329057 1 438 + 438 Gaps:20 100.00 458 88.65 0.0 ruvB-like protein 1
blastp_kegg lcl|mdm:103441877 1 438 + 438 Gaps:20 100.00 458 88.43 0.0 ruvB-like protein 1
blastp_kegg lcl|csv:101210899 1 438 + 438 Gaps:20 100.00 458 87.55 0.0 ruvB-like 1-like
blastp_kegg lcl|fve:101309228 1 438 + 438 Gaps:20 100.00 458 87.77 0.0 ruvB-like 1-like
blastp_kegg lcl|cmo:103486970 1 438 + 438 Gaps:20 100.00 458 87.34 0.0 ruvB-like protein 1
blastp_pdb 2c9o_C 4 437 + 434 Gaps:21 99.78 456 69.23 0.0 mol:protein length:456 RUVB-LIKE 1
blastp_pdb 2c9o_B 4 437 + 434 Gaps:21 99.78 456 69.23 0.0 mol:protein length:456 RUVB-LIKE 1
blastp_pdb 2c9o_A 4 437 + 434 Gaps:21 99.78 456 69.23 0.0 mol:protein length:456 RUVB-LIKE 1
blastp_pdb 2xsz_C 5 437 + 433 Gaps:16 94.55 367 67.72 2e-104 mol:protein length:367 RUVB-LIKE 1
blastp_pdb 2xsz_B 5 437 + 433 Gaps:16 94.55 367 67.72 2e-104 mol:protein length:367 RUVB-LIKE 1
blastp_pdb 2xsz_A 5 437 + 433 Gaps:16 94.55 367 67.72 2e-104 mol:protein length:367 RUVB-LIKE 1
blastp_pdb 2xsz_F 4 437 + 434 Gaps:22 90.21 378 44.57 7e-54 mol:protein length:378 RUVB-LIKE 2
blastp_pdb 2xsz_E 4 437 + 434 Gaps:22 90.21 378 44.57 7e-54 mol:protein length:378 RUVB-LIKE 2
blastp_pdb 2xsz_D 4 437 + 434 Gaps:22 90.21 378 44.57 7e-54 mol:protein length:378 RUVB-LIKE 2
blastp_uniprot_sprot sp|Q9FMR9|RIN1_ARATH 1 438 + 438 Gaps:20 100.00 458 84.93 0.0 RuvB-like protein 1 OS Arabidopsis thaliana GN RIN1 PE 1 SV 1
blastp_uniprot_sprot sp|Q9DE26|RUVB1_XENLA 4 437 + 434 Gaps:21 99.78 456 69.67 0.0 RuvB-like 1 OS Xenopus laevis GN ruvbl1 PE 2 SV 1
blastp_uniprot_sprot sp|P60123|RUVB1_RAT 4 437 + 434 Gaps:21 99.78 456 69.45 0.0 RuvB-like 1 OS Rattus norvegicus GN Ruvbl1 PE 1 SV 1
blastp_uniprot_sprot sp|P60122|RUVB1_MOUSE 4 437 + 434 Gaps:21 99.78 456 69.45 0.0 RuvB-like 1 OS Mus musculus GN Ruvbl1 PE 1 SV 1
blastp_uniprot_sprot sp|Q9Y265|RUVB1_HUMAN 4 437 + 434 Gaps:21 99.78 456 69.23 0.0 RuvB-like 1 OS Homo sapiens GN RUVBL1 PE 1 SV 1
blastp_uniprot_sprot sp|Q8AWW7|RUVB1_DANRE 4 437 + 434 Gaps:21 99.78 456 69.45 0.0 RuvB-like 1 OS Danio rerio GN ruvbl1 PE 2 SV 1
blastp_uniprot_sprot sp|Q0IFL2|RUVB1_AEDAE 4 437 + 434 Gaps:21 99.78 456 67.91 0.0 RuvB-like helicase 1 OS Aedes aegypti GN pont PE 3 SV 1
blastp_uniprot_sprot sp|Q9VH07|RUVB1_DROME 4 437 + 434 Gaps:21 99.78 456 67.69 0.0 RuvB-like helicase 1 OS Drosophila melanogaster GN pont PE 1 SV 1
blastp_uniprot_sprot sp|Q29AK9|RUVB1_DROPS 4 437 + 434 Gaps:21 99.78 456 67.69 0.0 RuvB-like helicase 1 OS Drosophila pseudoobscura pseudoobscura GN pont PE 3 SV 1
blastp_uniprot_sprot sp|Q4WPW8|RUVB1_ASPFU 4 438 + 435 Gaps:22 99.78 458 66.74 0.0 RuvB-like helicase 1 OS Neosartorya fumigata (strain ATCC MYA-4609 / Af293 / CBS 101355 / FGSC A1100) GN rvb1 PE 3 SV 1
rpsblast_cdd gnl|CDD|147949 17 397 + 381 Gaps:27 99.75 395 61.17 1e-171 pfam06068 TIP49 TIP49 C-terminus. This family consists of the C-terminal region of several eukaryotic and archaeal RuvB-like 1 (Pontin or TIP49a) and RuvB-like 2 (Reptin or TIP49b) proteins. The N-terminal domain contains the pfam00004 domain. In zebrafish the liebeskummer (lik) mutation causes development of hyperplastic embryonic hearts. lik encodes Reptin a component of a DNA-stimulated ATPase complex. Beta-catenin and Pontin a DNA-stimulated ATPase that is often part of complexes with Reptin are in the same genetic pathways. The Reptin/Pontin ratio serves to regulate heart growth during development at least in part via the beta-catenin pathway. TBP-interacting protein 49 (TIP49) was originally identified as a TBP-binding protein and two related proteins are encoded by individual genes tip49a and b. Although the function of this gene family has not been elucidated they are supposed to play a critical role in nuclear events because they interact with various kinds of nuclear factors and have DNA helicase activities.TIP49a has been suggested to act as an autoantigen in some patients with autoimmune diseases.

11 Domain Motifs

Analysis Begin End Length Domain Identifier Cross Ref Description Inter Pro
Gene3D 340 417 78 G3DSA:1.10.8.60 none none none
Gene3D 41 112 72 G3DSA:3.40.50.300 none none IPR027417
Gene3D 280 339 60 G3DSA:3.40.50.300 none none IPR027417
PANTHER 1 437 437 PTHR11093 none none IPR027238
Pfam 17 397 381 PF06068 none TIP49 C-terminus IPR010339
SMART 50 347 298 SM00382 none ATPases associated with a variety of cellular activities IPR003593
SUPERFAMILY 117 192 76 SSF50249 none none IPR012340
SUPERFAMILY 181 419 239 SSF52540 none none IPR027417
SUPERFAMILY 39 126 88 SSF52540 none none IPR027417
PRINTS 58 77 20 PR00830 none Endopeptidase La (Lon) serine protease (S16) signature none
PRINTS 358 376 19 PR00830 none Endopeptidase La (Lon) serine protease (S16) signature none

0 Localization

6 Qtllist

Qtl Name Chromosome Name Linkage Group Prox Marker Dist Marker Position QTL Pos One Pos Two Test Type Test Value R 2
Bourran2_2014_nSecLBD_3P Qrob_Chr08 8 s_1BN2OD_551 s_1B5AYF_599 17,17 0 43,51 lod 1,9229 4,4
Bourran2_2014_nLBD*_3P Qrob_Chr08 8 v_5216_549 v_11837_70 12,25 0 35,55 lod 2,5951 6
Bourran2_2014_nP*_3P Qrob_Chr08 8 v_5216_549 v_11837_70 12,19 0 31,97 lod 2,8472 6
Bourran2_2014_nPriLBD_3P Qrob_Chr08 8 v_5216_549 v_11837_70 12,36 0 30,43 lod 2,5806 5,1
Bourran2_2014_nEpis*_3P Qrob_Chr08 8 s_1DA4QW_688 s_1DNI7D_820 17,96 0 37,75 lod 2,9745 7,5
Bourran2_2014_nPriBD_3P Qrob_Chr11 11 v_11486_194 s_1AT3E_2335 5,54 0,4 20,6 lod 2,6345 5,9

0 Targeting