Protein : Qrob_P0674360.2 Q. robur
Protein Identifier  ? Qrob_P0674360.2 Organism . Name  Quercus robur
Score  100.0 Score Type  egn
Protein Description  (M=2) K10843 - DNA excision repair protein ERCC-3 [EC:3.6.4.12] Code Enzyme  EC:3.6.4.12
Gene Prediction Quality  validated Protein length 

Sequence

Length: 525  
Kegg Orthology  K10843
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0 Synonyms

5 GO Terms

Identifier Name Description
GO:0003677 DNA binding Any molecular function by which a gene product interacts selectively and non-covalently with DNA (deoxyribonucleic acid).
GO:0005524 ATP binding Interacting selectively and non-covalently with ATP, adenosine 5'-triphosphate, a universally important coenzyme and enzyme regulator.
GO:0016787 hydrolase activity Catalysis of the hydrolysis of various bonds, e.g. C-O, C-N, C-C, phosphoric anhydride bonds, etc. Hydrolase is the systematic name for any enzyme of EC class 3.
GO:0006289 nucleotide-excision repair A DNA repair process in which a small region of the strand surrounding the damage is removed from the DNA helix as an oligonucleotide. The small gap left in the DNA helix is filled in by the sequential action of DNA polymerase and DNA ligase. Nucleotide excision repair recognizes a wide range of substrates, including damage caused by UV irradiation (pyrimidine dimers and 6-4 photoproducts) and chemicals (intrastrand cross-links and bulky adducts).
GO:0004003 ATP-dependent DNA helicase activity Catalysis of the reaction: ATP + H2O = ADP + phosphate; this reaction drives the unwinding of the DNA helix.

29 Blast

Analysis Hit Start End Strand Length Note Hit Coverage Hit Length Hit Pident E Val Hit Description
blastp_kegg lcl|tcc:TCM_016301 1 513 + 513 Gaps:22 68.61 771 86.39 0.0 Xeroderma pigmentosum complementation group B 1 isoform 1
blastp_kegg lcl|vvi:100250174 1 513 + 513 Gaps:22 68.61 771 85.63 0.0 DNA repair helicase XPB1-like
blastp_kegg lcl|mus:103973317 2 513 + 512 Gaps:24 68.48 774 80.57 0.0 DNA repair helicase XPB1-like
blastp_kegg lcl|sot:102589513 2 513 + 512 Gaps:21 68.62 768 83.49 0.0 DNA repair helicase XPB1-like
blastp_kegg lcl|sly:101251406 2 513 + 512 Gaps:21 68.62 768 83.11 0.0 DNA repair helicase XPB1-like
blastp_kegg lcl|pmum:103337550 1 513 + 513 Gaps:22 68.54 766 86.48 0.0 DNA repair helicase XPB1
blastp_kegg lcl|pper:PRUPE_ppa001762mg 1 513 + 513 Gaps:24 68.62 768 85.96 0.0 hypothetical protein
blastp_kegg lcl|aly:ARALYDRAFT_916071 1 513 + 513 Gaps:26 70.53 767 79.30 0.0 DNA repair and transcription factor XPB1
blastp_kegg lcl|rcu:RCOM_1687530 1 513 + 513 Gaps:25 68.49 768 86.31 0.0 rad25/xp-B DNA repair helicase putative
blastp_kegg lcl|pda:103706419 2 513 + 512 Gaps:24 68.40 769 81.56 0.0 DNA repair helicase XPB1
blastp_pdb 2fwr_D 248 417 + 170 Gaps:25 30.72 472 31.72 5e-08 mol:protein length:472 DNA repair protein RAD25
blastp_pdb 2fwr_C 248 417 + 170 Gaps:25 30.72 472 31.72 5e-08 mol:protein length:472 DNA repair protein RAD25
blastp_pdb 2fwr_B 248 417 + 170 Gaps:25 30.72 472 31.72 5e-08 mol:protein length:472 DNA repair protein RAD25
blastp_pdb 2fwr_A 248 417 + 170 Gaps:25 30.72 472 31.72 5e-08 mol:protein length:472 DNA repair protein RAD25
blastp_uniprot_sprot sp|Q9FUG4|XPB2_ARATH 1 513 + 513 Gaps:26 71.54 766 78.10 0.0 DNA repair helicase XPB2 OS Arabidopsis thaliana GN XPB2 PE 2 SV 1
blastp_uniprot_sprot sp|Q38861|XPB1_ARATH 1 513 + 513 Gaps:21 68.84 767 80.68 0.0 DNA repair helicase XPB1 OS Arabidopsis thaliana GN XPB1 PE 2 SV 3
blastp_uniprot_sprot sp|O00835|ERCC3_DICDI 54 471 + 418 Gaps:51 56.62 800 59.38 8e-151 TFIIH basal transcription factor complex helicase repB subunit OS Dictyostelium discoideum GN repB PE 2 SV 1
blastp_uniprot_sprot sp|P49135|ERCC3_MOUSE 33 496 + 464 Gaps:56 64.11 783 49.00 5e-127 TFIIH basal transcription factor complex helicase XPB subunit OS Mus musculus GN Ercc3 PE 2 SV 1
blastp_uniprot_sprot sp|O13768|ERCC3_SCHPO 46 466 + 421 Gaps:40 55.60 804 53.69 2e-125 Probable DNA repair helicase ercc3 OS Schizosaccharomyces pombe (strain 972 / ATCC 24843) GN ercc3 PE 1 SV 1
blastp_uniprot_sprot sp|Q4G005|ERCC3_RAT 33 496 + 464 Gaps:53 64.07 782 48.10 3e-125 TFIIH basal transcription factor complex helicase XPB subunit OS Rattus norvegicus GN Ercc3 PE 2 SV 1
blastp_uniprot_sprot sp|Q7ZVV1|ERCC3_DANRE 33 496 + 464 Gaps:54 64.19 782 48.01 4e-125 TFIIH basal transcription factor complex helicase XPB subunit OS Danio rerio GN ercc3 PE 2 SV 1
blastp_uniprot_sprot sp|Q1RMT1|ERCC3_BOVIN 33 496 + 464 Gaps:53 64.07 782 48.30 4e-125 TFIIH basal transcription factor complex helicase XPB subunit OS Bos taurus GN ERCC3 PE 2 SV 1
blastp_uniprot_sprot sp|Q5ZKK7|ERCC3_CHICK 33 496 + 464 Gaps:53 63.58 788 48.50 1e-124 TFIIH basal transcription factor complex helicase XPB subunit OS Gallus gallus GN ERCC3 PE 2 SV 1
blastp_uniprot_sprot sp|Q60HG1|ERCC3_MACFA 33 496 + 464 Gaps:53 64.07 782 48.10 2e-124 TFIIH basal transcription factor complex helicase XPB subunit OS Macaca fascicularis GN ERCC3 PE 2 SV 1
rpsblast_cdd gnl|CDD|161952 48 513 + 466 Gaps:56 69.40 732 59.06 1e-180 TIGR00603 rad25 DNA repair helicase rad25. All proteins in this family for which functions are known are DNA-DNA helicases used for the initiation of nucleotide excision repair and transacription as part of the TFIIH complex.This family is based on the phylogenomic analysis of JA Eisen (1999 Ph.D. Thesis Stanford University).
rpsblast_cdd gnl|CDD|31261 237 465 + 229 Gaps:15 46.15 442 36.76 1e-26 COG1061 SSL2 DNA or RNA helicases of superfamily II [Transcription / DNA replication recombination and repair].
rpsblast_cdd gnl|CDD|197756 254 409 + 156 Gaps:21 78.11 201 19.11 7e-14 smart00487 DEXDc DEAD-like helicases superfamily.
rpsblast_cdd gnl|CDD|205803 62 153 + 92 Gaps:3 69.53 128 34.83 2e-12 pfam13625 Helicase_C_3 Helicase conserved C-terminal domain. This domain family is found in a wide variety of helicases and helicase-related proteins.
rpsblast_kog gnl|CDD|36339 30 524 + 495 Gaps:42 68.17 776 58.60 1e-164 KOG1123 KOG1123 KOG1123 RNA polymerase II transcription initiation/nucleotide excision repair factor TFIIH 3'-5' helicase subunit SSL2 [Transcription Replication recombination and repair].

14 Domain Motifs

Analysis Begin End Length Domain Identifier Cross Ref Description Inter Pro
SUPERFAMILY 221 413 193 SSF52540 none none IPR027417
Gene3D 255 413 159 G3DSA:3.40.50.300 none none IPR027417
PANTHER 5 413 409 PTHR11274 none none none
TIGRFAM 203 414 212 TIGR00603 none rad25: DNA repair helicase rad25 IPR001161
Pfam 260 413 154 PF04851 none Type III restriction enzyme, res subunit IPR006935
PANTHER 5 413 409 PTHR11274:SF0 none none none
Pfam 62 153 92 PF13625 none Helicase conserved C-terminal domain none
ProSiteProfiles 272 413 142 PS51192 none Superfamilies 1 and 2 helicase ATP-binding type-1 domain profile. IPR014001
PRINTS 61 81 21 PR00851 none Xeroderma pigmentosum group B protein signature IPR001161
PRINTS 242 268 27 PR00851 none Xeroderma pigmentosum group B protein signature IPR001161
PRINTS 273 295 23 PR00851 none Xeroderma pigmentosum group B protein signature IPR001161
PRINTS 380 400 21 PR00851 none Xeroderma pigmentosum group B protein signature IPR001161
SMART 257 439 183 SM00487 none DEAD-like helicases superfamily IPR014001
Pfam 424 466 43 PF00271 none Helicase conserved C-terminal domain IPR001650

0 Localization

2 Qtllist

Qtl Name Chromosome Name Linkage Group Prox Marker Dist Marker Position QTL Pos One Pos Two Test Type Test Value R 2
Bourran2_2015_nEpis_3P Qrob_Chr12 12 s_1AOES6_1466 s_1B0DDG_1094 28,97 28,55 30,1 lod 3.6 8.4
Bourran2_2015_nP_3P Qrob_Chr12 12 v_10140_295 v_838_303 16 14,69 18,01 lod 5.1 13.7

0 Targeting