Protein : Qrob_P0664340.2 Q. robur
Protein Identifier  ? Qrob_P0664340.2 Organism . Name  Quercus robur
Score  100.0 Score Type  egn
Protein Description  (M=3) K12817 - pre-mRNA-splicing factor 18 Gene Prediction Quality  validated
Protein length 

Sequence

Length: 289  
Kegg Orthology  K12817
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0 Synonyms

2 GO Terms

Identifier Name Description
GO:0005681 spliceosomal complex Any of a series of ribonucleoprotein complexes that contain snRNA(s) and small nuclear ribonucleoproteins (snRNPs), and are formed sequentially during the spliceosomal splicing of one or more substrate RNAs, and which also contain the RNA substrate(s) from the initial target RNAs of splicing, the splicing intermediate RNA(s), to the final RNA products. During cis-splicing, the initial target RNA is a single, contiguous RNA transcript, whether mRNA, snoRNA, etc., and the released products are a spliced RNA and an excised intron, generally as a lariat structure. During trans-splicing, there are two initial substrate RNAs, the spliced leader RNA and a pre-mRNA.
GO:0008380 RNA splicing The process of removing sections of the primary RNA transcript to remove sequences not present in the mature form of the RNA and joining the remaining sections to form the mature form of the RNA.

20 Blast

Analysis Hit Start End Strand Length Note Hit Coverage Hit Length Hit Pident E Val Hit Description
blastp_kegg lcl|gmx:100798833 1 275 + 275 Gaps:5 66.83 413 72.46 1e-129 pre-mRNA-splicing factor 18-like
blastp_kegg lcl|gmx:100785799 1 275 + 275 Gaps:4 66.91 411 73.45 4e-128 pre-mRNA-splicing factor 18-like
blastp_kegg lcl|csv:101228027 1 275 + 275 Gaps:14 67.38 420 69.96 4e-123 pre-mRNA-splicing factor 18-like
blastp_kegg lcl|csv:101204146 1 275 + 275 Gaps:14 67.38 420 69.96 4e-123 pre-mRNA-splicing factor 18-like
blastp_kegg lcl|pmum:103334132 1 275 + 275 Gaps:10 67.87 417 69.61 7e-123 pre-mRNA-splicing factor 18
blastp_kegg lcl|tcc:TCM_004356 1 275 + 275 Gaps:7 67.47 415 75.36 8e-123 Splicing factor Prp18 family protein isoform 1
blastp_kegg lcl|pper:PRUPE_ppa006327mg 1 275 + 275 Gaps:10 67.87 417 69.26 4e-122 hypothetical protein
blastp_kegg lcl|rcu:RCOM_0557340 1 275 + 275 Gaps:8 67.39 417 72.24 2e-120 potassium channel regulatory factor putative
blastp_kegg lcl|cic:CICLE_v10020348mg 1 275 + 275 Gaps:9 67.31 416 72.50 1e-118 hypothetical protein
blastp_kegg lcl|cit:102611778 1 275 + 275 Gaps:9 67.31 416 72.50 1e-118 pre-mRNA-splicing factor 18-like
blastp_uniprot_sprot sp|Q8BM39|PRP18_MOUSE 1 274 + 274 Gaps:50 70.18 342 35.00 9e-14 Pre-mRNA-splicing factor 18 OS Mus musculus GN Prpf18 PE 2 SV 1
blastp_uniprot_sprot sp|Q99633|PRP18_HUMAN 1 274 + 274 Gaps:50 70.18 342 35.00 3e-13 Pre-mRNA-splicing factor 18 OS Homo sapiens GN PRPF18 PE 1 SV 1
blastp_uniprot_sprot sp|Q2HJ41|PRP18_BOVIN 1 274 + 274 Gaps:50 70.18 342 35.00 4e-13 Pre-mRNA-splicing factor 18 OS Bos taurus GN PRPF18 PE 2 SV 1
blastp_uniprot_sprot sp|Q5RE03|PRP18_PONAB 1 274 + 274 Gaps:50 70.18 342 35.00 4e-13 Pre-mRNA-splicing factor 18 OS Pongo abelii GN PRPF18 PE 2 SV 1
blastp_uniprot_sprot sp|Q9JKB8|PRP18_RAT 1 274 + 274 Gaps:50 70.18 342 34.58 8e-13 Pre-mRNA-splicing factor 18 OS Rattus norvegicus GN Prpf18 PE 2 SV 1
blastp_uniprot_sprot sp|Q5EAV6|PRP18_XENLA 1 274 + 274 Gaps:54 70.18 342 33.75 3e-10 Pre-mRNA-splicing factor 18 OS Xenopus laevis GN prpf18 PE 2 SV 1
blastp_uniprot_sprot sp|Q6GMH0|PRP18_DANRE 1 274 + 274 Gaps:76 70.18 342 32.50 3e-09 Pre-mRNA-splicing factor 18 OS Danio rerio GN prpf18 PE 2 SV 1
rpsblast_cdd gnl|CDD|202426 223 274 + 52 none 36.11 144 44.23 5e-10 pfam02840 Prp18 Prp18 domain. The splicing factor Prp18 is required for the second step of pre-mRNA splicing. The structure of a large fragment of the Saccharomyces cerevisiae Prp18 is known. This fragment is fully active in yeast splicing in vitro and includes the sequences of Prp18 that have been evolutionarily conserved. The core structure consists of five alpha-helices that adopt a novel fold. The most highly conserved region of Prp18 a nearly invariant stretch of 19 aa forms part of a loop between two alpha-helices and may interact with the U5 small nuclear ribonucleoprotein particles.
rpsblast_cdd gnl|CDD|128776 95 139 + 45 Gaps:1 100.00 44 56.82 1e-07 smart00500 SFM Splicing Factor Motif present in Prp18 and Pr04.
rpsblast_kog gnl|CDD|38019 1 274 + 274 Gaps:43 69.50 341 38.82 2e-37 KOG2808 KOG2808 KOG2808 U5 snRNP-associated RNA splicing factor [RNA processing and modification].

8 Domain Motifs

Analysis Begin End Length Domain Identifier Cross Ref Description Inter Pro
SUPERFAMILY 88 130 43 SSF158230 none none none
PANTHER 1 274 274 PTHR13007:SF19 none none none
Pfam 222 274 53 PF02840 none Prp18 domain IPR004098
PANTHER 1 274 274 PTHR13007 none none none
SMART 95 146 52 SM00500 none Splicing Factor Motif, present in Prp18 and Pr04 IPR003648
Pfam 100 129 30 PF08799 none pre-mRNA processing factor 4 (PRP4) like IPR014906
SUPERFAMILY 197 274 78 SSF47938 none none IPR004098
Gene3D 201 274 74 G3DSA:1.20.940.10 none none IPR004098

0 Localization

4 Qtllist

Qtl Name Chromosome Name Linkage Group Prox Marker Dist Marker Position QTL Pos One Pos Two Test Type Test Value R 2
Bourran2_2015_nEpiBC_3P Qrob_Chr12 12 s_1B73S5_217 v_7050_211 28,31 26,37 28,45 lod 4.5 11.6
Bourran2_2015_nP_3P Qrob_Chr12 12 v_10140_295 v_838_303 16 14,69 18,01 lod 5.1 13.7
Bourran2_2015_nSecLBD_3P Qrob_Chr12 12 s_A4YYC_633 s_2F1IZB_703 18,64 18,01 21,53 lod 6.5 17.2
Bourran2_2014_nSeqBC_3P Qrob_Chr12 12 s_1EO8V5_710 s_1A2VMU_355 11,04 0 32,58 lod 1,7196 4,7

0 Targeting