Protein : Qrob_P0632270.2 Q. robur
Protein Identifier  ? Qrob_P0632270.2 Organism . Name  Quercus robur
Score  100.0 Score Type  egn
Protein Description  (M=1) 1.1.1.34 - Hydroxymethylglutaryl-CoA reductase (NADPH). Code Enzyme  EC:1.1.1.34
Gene Prediction Quality  validated Protein length 

Sequence

Length: 578  
Kegg Orthology  K00021
Paste the following link
Lists
This Protein isn't in any lists. Upload a list.

Sequence Feature Displayer

Protein Sequence Displayer

J Browse Displayer

0 Synonyms

8 GO Terms

Identifier Name Description
GO:0055114 oxidation-reduction process A metabolic process that results in the removal or addition of one or more electrons to or from a substance, with or without the concomitant removal or addition of a proton or protons.
GO:0016021 integral component of membrane The component of a membrane consisting of the gene products and protein complexes having at least some part of their peptide sequence embedded in the hydrophobic region of the membrane.
GO:0008299 isoprenoid biosynthetic process The chemical reactions and pathways resulting in the formation of any isoprenoid compound, isoprene (2-methylbuta-1,3-diene) or compounds containing or derived from linked isoprene (3-methyl-2-butenylene) residues.
GO:0016616 oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor Catalysis of an oxidation-reduction (redox) reaction in which a CH-OH group acts as a hydrogen or electron donor and reduces NAD+ or NADP.
GO:0050661 NADP binding Interacting selectively and non-covalently with nicotinamide-adenine dinucleotide phosphate, a coenzyme involved in many redox and biosynthetic reactions; binding may be to either the oxidized form, NADP+, or the reduced form, NADPH.
GO:0050662 coenzyme binding Interacting selectively and non-covalently with a coenzyme, any of various nonprotein organic cofactors that are required, in addition to an enzyme and a substrate, for an enzymatic reaction to proceed.
GO:0004420 hydroxymethylglutaryl-CoA reductase (NADPH) activity Catalysis of the reaction: (R)-mevalonate + CoA + 2 NADP(+) = (S)-3-hydroxy-3-methylglutaryl-CoA + 2 H(+) + 2 NADPH.
GO:0015936 coenzyme A metabolic process The chemical reactions and pathways involving coenzyme A, 3'-phosphoadenosine-(5')diphospho(4')pantatheine, an acyl carrier in many acylation and acyl-transfer reactions in which the intermediate is a thiol ester.

38 Blast

Analysis Hit Start End Strand Length Note Hit Coverage Hit Length Hit Pident E Val Hit Description
blastp_kegg lcl|rcu:RCOM_1602200 1 577 + 577 Gaps:13 100.00 576 82.81 0.0 hmg-CoA reductase putative (EC:1.1.1.34)
blastp_kegg lcl|pop:POPTR_0002s00570g 1 577 + 577 Gaps:17 100.00 588 79.59 0.0 POPTRDRAFT_829982 hydroxymethylglutaryl-CoA reductase family protein
blastp_kegg lcl|vvi:100265082 30 577 + 548 Gaps:10 94.10 593 81.36 0.0 3-hydroxy-3-methylglutaryl-coenzyme A reductase 1-like
blastp_kegg lcl|aly:ARALYDRAFT_316570 1 573 + 573 Gaps:19 91.34 635 79.14 0.0 HMG1 3-hydroxy-3-methylglutaryl CoA reductase
blastp_kegg lcl|gmx:100784330 1 576 + 576 Gaps:26 100.00 556 81.83 0.0 3-hydroxy-3-methylglutaryl-coenzyme A reductase 1-like
blastp_kegg lcl|cam:101507469 1 577 + 577 Gaps:12 100.00 575 78.26 0.0 3-hydroxy-3-methylglutaryl-coenzyme A reductase 1-like
blastp_kegg lcl|cmo:103502601 24 577 + 554 Gaps:11 96.25 587 79.65 0.0 Cm-HMGR HMG-CoA 3-hydroxy-3-methylglutaryl-coenzyme A reductase 1 (EC:1.1.1.34)
blastp_kegg lcl|csv:101225491 27 577 + 551 Gaps:4 94.07 590 80.36 0.0 3-hydroxy-3-methylglutaryl-coenzyme A reductase 1-like
blastp_kegg lcl|csv:101210779 27 577 + 551 Gaps:4 94.07 590 80.36 0.0 3-hydroxy-3-methylglutaryl-coenzyme A reductase 1-like
blastp_kegg lcl|ath:AT1G76490 1 573 + 573 Gaps:15 90.65 642 77.49 0.0 HMG1 3-hydroxy-3-methylglutaryl-coenzyme A reductase 1
blastp_pdb 1hwl_D 134 575 + 442 Gaps:14 95.93 467 53.12 2e-165 mol:protein length:467 HMG-COA REDUCTASE
blastp_pdb 1hwl_C 134 575 + 442 Gaps:14 95.93 467 53.12 2e-165 mol:protein length:467 HMG-COA REDUCTASE
blastp_pdb 1hwl_B 134 575 + 442 Gaps:14 95.93 467 53.12 2e-165 mol:protein length:467 HMG-COA REDUCTASE
blastp_pdb 1hwl_A 134 575 + 442 Gaps:14 95.93 467 53.12 2e-165 mol:protein length:467 HMG-COA REDUCTASE
blastp_pdb 1hwk_D 134 575 + 442 Gaps:14 95.93 467 53.12 2e-165 mol:protein length:467 HMG-COA REDUCTASE
blastp_pdb 1hwk_C 134 575 + 442 Gaps:14 95.93 467 53.12 2e-165 mol:protein length:467 HMG-COA REDUCTASE
blastp_pdb 1hwk_B 134 575 + 442 Gaps:14 95.93 467 53.12 2e-165 mol:protein length:467 HMG-COA REDUCTASE
blastp_pdb 1hwk_A 134 575 + 442 Gaps:14 95.93 467 53.12 2e-165 mol:protein length:467 HMG-COA REDUCTASE
blastp_pdb 1hwj_D 134 575 + 442 Gaps:14 95.93 467 53.12 2e-165 mol:protein length:467 HMG-COA REDUCTASE
blastp_pdb 1hwj_C 134 575 + 442 Gaps:14 95.93 467 53.12 2e-165 mol:protein length:467 HMG-COA REDUCTASE
blastp_uniprot_sprot sp|P29057|HMDH1_HEVBR 33 577 + 545 Gaps:10 96.52 575 83.96 0.0 3-hydroxy-3-methylglutaryl-coenzyme A reductase 1 OS Hevea brasiliensis GN HMGR1 PE 2 SV 1
blastp_uniprot_sprot sp|P14891|HMDH1_ARATH 1 573 + 573 Gaps:15 98.31 592 77.49 0.0 3-hydroxy-3-methylglutaryl-coenzyme A reductase 1 OS Arabidopsis thaliana GN HMG1 PE 1 SV 1
blastp_uniprot_sprot sp|Q01559|HMDH_NICSY 1 577 + 577 Gaps:31 100.00 604 75.17 0.0 3-hydroxy-3-methylglutaryl-coenzyme A reductase OS Nicotiana sylvestris GN HMGR PE 2 SV 1
blastp_uniprot_sprot sp|P48020|HMDH1_SOLTU 1 574 + 574 Gaps:34 100.00 596 74.50 0.0 3-hydroxy-3-methylglutaryl-coenzyme A reductase 1 OS Solanum tuberosum GN HMG1 PE 2 SV 1
blastp_uniprot_sprot sp|Q03163|HMDH_CATRO 1 577 + 577 Gaps:31 98.84 601 73.23 0.0 3-hydroxy-3-methylglutaryl-coenzyme A reductase OS Catharanthus roseus GN HMGR PE 2 SV 1
blastp_uniprot_sprot sp|Q41438|HMDH3_SOLTU 1 574 + 574 Gaps:8 100.00 574 75.09 0.0 3-hydroxy-3-methylglutaryl-coenzyme A reductase 3 OS Solanum tuberosum GN HMG3 PE 2 SV 1
blastp_uniprot_sprot sp|Q9XEL8|HMDH2_CAPAN 26 577 + 552 Gaps:24 95.36 604 74.83 0.0 3-hydroxy-3-methylglutaryl-coenzyme A reductase 2 OS Capsicum annuum GN HMGR2 PE 2 SV 1
blastp_uniprot_sprot sp|P48022|HMDH2_SOLLC 1 577 + 577 Gaps:31 100.00 602 73.59 0.0 3-hydroxy-3-methylglutaryl-coenzyme A reductase 2 OS Solanum lycopersicum GN HMG2 PE 3 SV 1
blastp_uniprot_sprot sp|Q41437|HMDH2_SOLTU 1 570 + 570 Gaps:32 99.50 595 73.31 0.0 3-hydroxy-3-methylglutaryl-coenzyme A reductase 2 OS Solanum tuberosum GN HMG2 PE 2 SV 1
blastp_uniprot_sprot sp|O64967|HMDH2_GOSHI 1 577 + 577 Gaps:69 100.00 628 70.22 0.0 3-hydroxy-3-methylglutaryl-coenzyme A reductase 2 OS Gossypium hirsutum GN HMG2 PE 3 SV 1

28 Domain Motifs

Analysis Begin End Length Domain Identifier Cross Ref Description Inter Pro
SUPERFAMILY 284 400 117 SSF55035 "KEGG:00900+1.1.1.34","MetaCyc:PWY-6174","MetaCyc:PWY-7391","MetaCyc:PWY-7524","MetaCyc:PWY-922","UniPathway:UPA00058" none IPR009023
Gene3D 284 399 116 G3DSA:3.30.70.420 "KEGG:00900+1.1.1.34","MetaCyc:PWY-6174","MetaCyc:PWY-7391","MetaCyc:PWY-7524","MetaCyc:PWY-922","UniPathway:UPA00058" none IPR009023
Phobius 1 43 43 NON_CYTOPLASMIC_DOMAIN none Region of a membrane-bound protein predicted to be outside the membrane, in the extracellular region. none
Phobius 106 532 427 NON_CYTOPLASMIC_DOMAIN none Region of a membrane-bound protein predicted to be outside the membrane, in the extracellular region. none
Phobius 86 105 20 TRANSMEMBRANE none Region of a membrane-bound protein predicted to be embedded in the membrane. none
Pfam 188 567 380 PF00368 "KEGG:00900+1.1.1.34","MetaCyc:PWY-6174","MetaCyc:PWY-7391","MetaCyc:PWY-7524","MetaCyc:PWY-922","UniPathway:UPA00058" Hydroxymethylglutaryl-coenzyme A reductase IPR002202
PANTHER 39 577 539 PTHR10572 "KEGG:00900+1.1.1.34","MetaCyc:PWY-6174","MetaCyc:PWY-7391","MetaCyc:PWY-7524","MetaCyc:PWY-922","UniPathway:UPA00058";signature_desc=3-HYDROXY-3-METHYLGLUTARYL-COENZYME A REDUCTASE none IPR002202
Phobius 533 559 27 TRANSMEMBRANE none Region of a membrane-bound protein predicted to be embedded in the membrane. none
Gene3D 400 569 170 G3DSA:3.90.770.10 "KEGG:00900+1.1.1.34","MetaCyc:PWY-6174","MetaCyc:PWY-7391","MetaCyc:PWY-7524","MetaCyc:PWY-922","UniPathway:UPA00058" none IPR023074
Gene3D 234 280 47 G3DSA:3.90.770.10 "KEGG:00900+1.1.1.34","MetaCyc:PWY-6174","MetaCyc:PWY-7391","MetaCyc:PWY-7524","MetaCyc:PWY-922","UniPathway:UPA00058" none IPR023074
ProSitePatterns 343 357 15 PS00066 "KEGG:00900+1.1.1.34","MetaCyc:PWY-6174","MetaCyc:PWY-7391","MetaCyc:PWY-7524","MetaCyc:PWY-922","UniPathway:UPA00058" Hydroxymethylglutaryl-coenzyme A reductases signature 1. IPR023076
SUPERFAMILY 159 281 123 SSF56542 "KEGG:00900+1.1.1.34","MetaCyc:PWY-6174","MetaCyc:PWY-7391","MetaCyc:PWY-7524","MetaCyc:PWY-922","UniPathway:UPA00058" none IPR009029
SUPERFAMILY 398 556 159 SSF56542 "KEGG:00900+1.1.1.34","MetaCyc:PWY-6174","MetaCyc:PWY-7391","MetaCyc:PWY-7524","MetaCyc:PWY-922","UniPathway:UPA00058" none IPR009029
Gene3D 158 233 76 G3DSA:1.10.3270.10 "KEGG:00900+1.1.1.34","MetaCyc:PWY-6174","MetaCyc:PWY-7391","MetaCyc:PWY-7524","MetaCyc:PWY-922","UniPathway:UPA00058" none IPR023282
TIGRFAM 163 567 405 TIGR00533 "KEGG:00900+1.1.1.34","MetaCyc:PWY-6174","MetaCyc:PWY-7391","MetaCyc:PWY-7524","MetaCyc:PWY-922","UniPathway:UPA00058" HMG_CoA_R_NADP: hydroxymethylglutaryl-CoA reductase (NADPH) IPR004554
Phobius 560 577 18 CYTOPLASMIC_DOMAIN none Region of a membrane-bound protein predicted to be outside the membrane, in the cytoplasm. none
Phobius 66 85 20 CYTOPLASMIC_DOMAIN none Region of a membrane-bound protein predicted to be outside the membrane, in the cytoplasm. none
ProSitePatterns 498 505 8 PS00318 "KEGG:00900+1.1.1.34","MetaCyc:PWY-6174","MetaCyc:PWY-7391","MetaCyc:PWY-7524","MetaCyc:PWY-922","UniPathway:UPA00058" Hydroxymethylglutaryl-coenzyme A reductases signature 2. IPR023076
PANTHER 39 577 539 PTHR10572:SF2 none none none
ProSiteProfiles 163 567 405 PS50065 "KEGG:00900+1.1.1.34","MetaCyc:PWY-6174","MetaCyc:PWY-7391","MetaCyc:PWY-7524","MetaCyc:PWY-922","UniPathway:UPA00058" Hydroxymethylglutaryl-coenzyme A reductases family profile. IPR002202
ProSitePatterns 552 565 14 PS01192 "KEGG:00900+1.1.1.34","MetaCyc:PWY-6174","MetaCyc:PWY-7391","MetaCyc:PWY-7524","MetaCyc:PWY-922","UniPathway:UPA00058" Hydroxymethylglutaryl-coenzyme A reductases signature 3. IPR023076
Phobius 44 65 22 TRANSMEMBRANE none Region of a membrane-bound protein predicted to be embedded in the membrane. none
PRINTS 341 359 19 PR00071 "KEGG:00900+1.1.1.34","MetaCyc:PWY-6174","MetaCyc:PWY-7391","MetaCyc:PWY-7524","MetaCyc:PWY-922","UniPathway:UPA00058" Hydroxymethylglutaryl-coenzyme A reductase signature IPR002202
PRINTS 381 406 26 PR00071 "KEGG:00900+1.1.1.34","MetaCyc:PWY-6174","MetaCyc:PWY-7391","MetaCyc:PWY-7524","MetaCyc:PWY-922","UniPathway:UPA00058" Hydroxymethylglutaryl-coenzyme A reductase signature IPR002202
PRINTS 486 507 22 PR00071 "KEGG:00900+1.1.1.34","MetaCyc:PWY-6174","MetaCyc:PWY-7391","MetaCyc:PWY-7524","MetaCyc:PWY-922","UniPathway:UPA00058" Hydroxymethylglutaryl-coenzyme A reductase signature IPR002202
PRINTS 223 244 22 PR00071 "KEGG:00900+1.1.1.34","MetaCyc:PWY-6174","MetaCyc:PWY-7391","MetaCyc:PWY-7524","MetaCyc:PWY-922","UniPathway:UPA00058" Hydroxymethylglutaryl-coenzyme A reductase signature IPR002202
PRINTS 250 270 21 PR00071 "KEGG:00900+1.1.1.34","MetaCyc:PWY-6174","MetaCyc:PWY-7391","MetaCyc:PWY-7524","MetaCyc:PWY-922","UniPathway:UPA00058" Hydroxymethylglutaryl-coenzyme A reductase signature IPR002202
PRINTS 432 458 27 PR00071 "KEGG:00900+1.1.1.34","MetaCyc:PWY-6174","MetaCyc:PWY-7391","MetaCyc:PWY-7524","MetaCyc:PWY-922","UniPathway:UPA00058" Hydroxymethylglutaryl-coenzyme A reductase signature IPR002202

3 Localization

Analysis Start End Length
TMHMM 537 559 22
TMHMM 86 108 22
TMHMM 43 65 22

16 Qtllist

Qtl Name Chromosome Name Linkage Group Prox Marker Dist Marker Position QTL Pos One Pos Two Test Type Test Value R 2
Bourran1_2003_QTL2_peak_Bud_burst_A4 Qrob_Chr02 2 s_1B0H8U_259 s_1CB1VL_554 17 0 87 lod 3,3 8,7
NancyGreenhouseCO2_2001_ambient_elevated_leaf_cellulose_QTL2_d13Cf Qrob_Chr02 2 s_1AQA4Z_1644 s_1AK5QX_947 53.67 14,01 79,68 lod 5.6594 0.03
Bourran1_2004_QTL2_peak_Bud_burst_3P Qrob_Chr02 2 s_1AW12F_382 s_1A77MR_223 42 6 64 lod 3,6 9,6
Bourran2_2002_QTL9_peak_Bud_burst_A4 Qrob_Chr02 2 s_1BFNDA_375 s_1A3VA1_2139 32,5 17 62 lod 3,1 4,2
Bourran2_2003_QTL8_peak_Bud_burst_3P Qrob_Chr02 2 s_1ANG6_1446 v_11270_161 40 0 72 lod 4,4 9,9
Bourran2_2014_nP_A4 Qrob_Chr11 11 s_1B58GB_1413 s_1A5BYY_1671 11,15 0 42,38 lod 1,8913 4,5
Bourran2_2015_nP_A4 Qrob_Chr02 2 s_1A0FUE_1868 s_1A1UAI_500 20,64 20,47 21,36 lod 5.8 10.9
Bourran2_2015_nPriLBD_A4 Qrob_Chr02 2 s_1CP5DI_1183 s_1A63ZX_1277 24,87 24,63 26,18 lod 3.8 7
Bourran2_2015_nEpis_A4 Qrob_Chr09 9 v_15847_485 v_8329_369 34,94 34,88 37,45 lod 3.1 7
Bourran1_2003_QTL1_peak_Bud_burst_3P Qrob_Chr02 2 s_1AR8KI_1183 s_1B0QB1_473 22 6 41 lod 4,2 11,5
Bourran1_2004_QTL3_peak_Bud_burst_A4 Qrob_Chr02 2 s_1B0H8U_259 s_1CB1VL_554 17 0 46 lod 2,9 6,4
Bourran2_2015_nEpiBC_A4 Qrob_Chr07 7 s_1DP9TW_798 v_8128_173 22,61 22,14 22,73 lod 3.1 8.5
Champenoux_2015_nEpis_A4 Qrob_Chr02 2 s_1BAGIZ_823 s_1BN4CB_644 23,06 23,06 23,06 lod 4.9 11
Champenoux_2015_nP_A4 Qrob_Chr02 2 s_1BN4CB_644 v_508_128 23,76 23,06 24,51 lod 2.8 6.2
Champenoux_2015_nPriLBD_A4 Qrob_Chr02 2 s_1CP5DI_1183 s_1A63ZX_1277 25,35 24,63 26,18 lod 4.0 8.7
Champenoux_2015_nSecLBD_A4 Qrob_Chr02 2 s_1AN4ZM_1665 v_8587_238 18,52 18,89 18,27 lod 3.2 7.4

0 Targeting