Protein : Qrob_P0612380.2 Q. robur
Protein Identifier  ? Qrob_P0612380.2 Organism . Name  Quercus robur
Score  0.0 Score Type  egn
Protein Description  (M=4) 1.14.13.132 - Squalene monooxygenase. Code Enzyme  EC:1.14.13.132
Gene Prediction Quality  validated Protein length 

Sequence

Length: 459  
Kegg Orthology  K00511
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0 Synonyms

4 GO Terms

Identifier Name Description
GO:0055114 oxidation-reduction process A metabolic process that results in the removal or addition of one or more electrons to or from a substance, with or without the concomitant removal or addition of a proton or protons.
GO:0050660 flavin adenine dinucleotide binding Interacting selectively and non-covalently with FAD, flavin-adenine dinucleotide, the coenzyme or the prosthetic group of various flavoprotein oxidoreductase enzymes, in either the oxidized form, FAD, or the reduced form, FADH2.
GO:0016021 integral component of membrane The component of a membrane consisting of the gene products and protein complexes having at least some part of their peptide sequence embedded in the hydrophobic region of the membrane.
GO:0004506 squalene monooxygenase activity Catalysis of the reaction: H(+) + NADPH + O(2) + squalene = (S)-2,3-epoxysqualene + H(2)O + NADP(+).

28 Blast

Analysis Hit Start End Strand Length Note Hit Coverage Hit Length Hit Pident E Val Hit Description
blastp_kegg lcl|rcu:RCOM_0859900 9 455 + 447 none 69.63 642 91.28 0.0 Squalene monooxygenase putative (EC:1.14.99.7)
blastp_kegg lcl|cit:102616721 9 455 + 447 none 72.80 614 90.38 0.0 squalene epoxidase 3-like
blastp_kegg lcl|tcc:TCM_000850 8 454 + 447 none 73.64 607 90.38 0.0 Squalene monooxygenase isoform 1
blastp_kegg lcl|cic:CICLE_v10025367mg 8 455 + 448 none 86.15 520 89.73 0.0 hypothetical protein
blastp_kegg lcl|pop:POPTR_0007s14670g 8 454 + 447 none 73.04 612 89.49 0.0 POPTRDRAFT_832433 hypothetical protein
blastp_kegg lcl|tcc:TCM_034641 2 455 + 454 none 86.81 523 87.22 0.0 Squalene monooxygenase isoform 1
blastp_kegg lcl|vvi:100262930 2 455 + 454 none 86.97 522 88.11 0.0 squalene monooxygenase-like
blastp_kegg lcl|csv:101204949 2 454 + 453 none 86.45 524 86.53 0.0 squalene monooxygenase-like
blastp_kegg lcl|cmo:103493632 2 454 + 453 none 86.45 524 86.31 0.0 squalene monooxygenase-like
blastp_kegg lcl|pper:PRUPE_ppa003991mg 8 452 + 445 none 83.02 536 88.09 0.0 hypothetical protein
blastp_uniprot_sprot sp|O48651|ERG1_PANGI 2 454 + 453 none 84.04 539 80.35 0.0 Squalene monooxygenase OS Panax ginseng PE 2 SV 1
blastp_uniprot_sprot sp|Q9SM02|ERG14_ARATH 2 454 + 453 Gaps:1 85.50 531 79.30 0.0 Squalene epoxidase 1 OS Arabidopsis thaliana GN SQE1 PE 1 SV 1
blastp_uniprot_sprot sp|Q8VYH2|ERG16_ARATH 8 451 + 444 none 84.57 525 81.53 0.0 Squalene epoxidase 3 OS Arabidopsis thaliana GN SQE3 PE 1 SV 1
blastp_uniprot_sprot sp|O81000|ERG15_ARATH 2 452 + 451 none 77.09 585 79.38 0.0 Squalene epoxidase 2 mitochondrial OS Arabidopsis thaliana GN SQE2 PE 1 SV 1
blastp_uniprot_sprot sp|O65404|ERG11_ARATH 2 451 + 450 Gaps:3 87.79 516 50.33 5e-163 Squalene epoxidase 5 OS Arabidopsis thaliana GN SQE5 PE 2 SV 2
blastp_uniprot_sprot sp|O65402|ERG12_ARATH 2 451 + 450 Gaps:4 87.81 517 48.90 5e-159 Squalene epoxidase 6 OS Arabidopsis thaliana GN SQE6 PE 2 SV 1
blastp_uniprot_sprot sp|O65726|ERG12_BRANA 2 451 + 450 Gaps:2 87.26 518 47.12 9e-155 Squalene monooxygenase 1 2 OS Brassica napus GN SQP1 2 PE 2 SV 1
blastp_uniprot_sprot sp|O65727|ERG11_BRANA 2 451 + 450 Gaps:13 87.15 506 50.34 9e-154 Squalene monooxygenase 1 1 OS Brassica napus GN SQP1 1 PE 2 SV 1
blastp_uniprot_sprot sp|O65403|ERG13_ARATH 9 450 + 442 Gaps:5 86.63 516 46.98 7e-145 Squalene epoxidase 4 OS Arabidopsis thaliana GN SQE4 PE 2 SV 1
blastp_uniprot_sprot sp|Q14534|ERG1_HUMAN 1 434 + 434 Gaps:13 75.78 574 46.44 1e-116 Squalene monooxygenase OS Homo sapiens GN SQLE PE 1 SV 3
rpsblast_cdd gnl|CDD|178566 9 451 + 443 Gaps:3 86.77 514 50.22 1e-148 PLN02985 PLN02985 squalene monooxygenase.
rpsblast_cdd gnl|CDD|192047 141 414 + 274 Gaps:4 100.00 276 60.51 1e-132 pfam08491 SE Squalene epoxidase. This domain is found in squalene epoxidase (SE) and related proteins which are found in taxonomically diverse groups of eukaryotes and also in bacteria. SE was first cloned from Saccharomyces cerevisiae where it was named ERG1. It contains a putative FAD binding site and is a key enzyme in the sterol biosynthetic pathway. Putative transmembrane regions are found to the protein's C-terminus.
rpsblast_cdd gnl|CDD|185578 9 437 + 429 Gaps:78 84.48 567 38.62 1e-113 PTZ00367 PTZ00367 squalene epoxidase Provisional.
rpsblast_cdd gnl|CDD|30999 13 368 + 356 Gaps:16 89.92 387 22.99 3e-29 COG0654 UbiH 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases [Coenzyme metabolism / Energy production and conversion].
rpsblast_cdd gnl|CDD|30989 13 346 + 334 Gaps:38 83.33 396 20.61 7e-09 COG0644 FixC Dehydrogenases (flavoproteins) [Energy production and conversion].
rpsblast_cdd gnl|CDD|180451 94 158 + 65 Gaps:2 15.97 407 35.38 3e-08 PRK06185 PRK06185 hypothetical protein Provisional.
rpsblast_cdd gnl|CDD|136171 9 341 + 333 Gaps:36 85.31 388 24.47 9e-08 PRK07045 PRK07045 putative monooxygenase Reviewed.
rpsblast_kog gnl|CDD|36512 9 452 + 444 Gaps:1 87.43 509 70.79 0.0 KOG1298 KOG1298 KOG1298 Squalene monooxygenase [Lipid transport and metabolism].

14 Domain Motifs

Analysis Begin End Length Domain Identifier Cross Ref Description Inter Pro
Gene3D 281 300 20 G3DSA:3.50.50.60 none none none
Gene3D 12 165 154 G3DSA:3.50.50.60 none none none
SUPERFAMILY 256 366 111 SSF51905 none none none
SUPERFAMILY 12 162 151 SSF51905 none none none
Phobius 413 431 19 TRANSMEMBRANE none Region of a membrane-bound protein predicted to be embedded in the membrane. none
Phobius 363 381 19 TRANSMEMBRANE none Region of a membrane-bound protein predicted to be embedded in the membrane. none
PANTHER 9 452 444 PTHR10835 none none none
Phobius 388 407 20 TRANSMEMBRANE none Region of a membrane-bound protein predicted to be embedded in the membrane. none
Phobius 382 387 6 CYTOPLASMIC_DOMAIN none Region of a membrane-bound protein predicted to be outside the membrane, in the cytoplasm. none
Phobius 408 412 5 NON_CYTOPLASMIC_DOMAIN none Region of a membrane-bound protein predicted to be outside the membrane, in the extracellular region. none
Phobius 1 362 362 NON_CYTOPLASMIC_DOMAIN none Region of a membrane-bound protein predicted to be outside the membrane, in the extracellular region. none
Gene3D 224 280 57 G3DSA:3.30.9.10 none none none
Pfam 142 414 273 PF08491 "KEGG:00100+1.14.13.132","KEGG:00909+1.14.13.132","MetaCyc:PWY-5670","MetaCyc:PWY-6098","UniPathway:UPA00767" Squalene epoxidase IPR013698
Phobius 432 458 27 CYTOPLASMIC_DOMAIN none Region of a membrane-bound protein predicted to be outside the membrane, in the cytoplasm. none

0 Localization

0 Qtllist

0 Targeting