Protein : Qrob_P0577520.2 Q. robur
Protein Identifier  ? Qrob_P0577520.2 Organism . Name  Quercus robur
Score  99.1 Score Type  egn
Protein Description  (M=5) 2.3.3.13 - 2-isopropylmalate synthase. Code Enzyme  EC:2.3.3.13
Gene Prediction Quality  validated Protein length 

Sequence

Length: 298  
Kegg Orthology  K01649
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0 Synonyms

3 GO Terms

Identifier Name Description
GO:0003824 catalytic activity Catalysis of a biochemical reaction at physiological temperatures. In biologically catalyzed reactions, the reactants are known as substrates, and the catalysts are naturally occurring macromolecular substances known as enzymes. Enzymes possess specific binding sites for substrates, and are usually composed wholly or largely of protein, but RNA that has catalytic activity (ribozyme) is often also regarded as enzymatic.
GO:0003852 2-isopropylmalate synthase activity Catalysis of the reaction: 3-methyl-2-oxobutanoate + acetyl-CoA + H(2)O = (2S)-2-isopropylmalate + CoA + H(+).
GO:0009098 leucine biosynthetic process The chemical reactions and pathways resulting in the formation of leucine, 2-amino-4-methylpentanoic acid.

41 Blast

Analysis Hit Start End Strand Length Note Hit Coverage Hit Length Hit Pident E Val Hit Description
blastp_kegg lcl|pper:PRUPE_ppa004868mg 2 296 + 295 none 60.45 488 89.15 0.0 hypothetical protein
blastp_kegg lcl|pmum:103331792 2 296 + 295 Gaps:1 46.76 633 88.18 0.0 2-isopropylmalate synthase 1 chloroplastic-like
blastp_kegg lcl|pxb:103942671 2 296 + 295 none 69.91 422 85.08 2e-179 2-isopropylmalate synthase 1 chloroplastic-like
blastp_kegg lcl|cic:CICLE_v10020218mg 2 296 + 295 none 68.13 433 83.05 8e-174 hypothetical protein
blastp_kegg lcl|pop:POPTR_0005s08480g 2 287 + 286 none 58.49 489 83.92 7e-172 POPTRDRAFT_861364 hypothetical protein
blastp_kegg lcl|cit:102620455 2 296 + 295 none 47.58 620 83.05 1e-170 2-isopropylmalate synthase 1 chloroplastic-like
blastp_kegg lcl|tcc:TCM_020103 2 296 + 295 Gaps:33 49.92 657 77.13 3e-169 2-isopropylmalate synthase 1 isoform 1
blastp_kegg lcl|eus:EUTSA_v10007073mg 2 295 + 294 none 47.04 625 80.27 1e-168 hypothetical protein
blastp_kegg lcl|cmo:103496846 2 281 + 280 none 43.68 641 85.00 3e-168 2-isopropylmalate synthase 2 chloroplastic-like
blastp_kegg lcl|csv:101224798 2 281 + 280 none 43.82 639 84.29 1e-167 2-isopropylmalate synthase 2 chloroplastic-like
blastp_pdb 3rmj_B 2 125 + 124 Gaps:6 32.43 370 54.17 1e-30 mol:protein length:370 2-isopropylmalate synthase
blastp_pdb 3rmj_A 2 125 + 124 Gaps:6 32.43 370 54.17 1e-30 mol:protein length:370 2-isopropylmalate synthase
blastp_pdb 3eeg_B 2 75 + 74 Gaps:2 22.15 325 55.56 2e-16 mol:protein length:325 2-isopropylmalate synthase
blastp_pdb 3eeg_A 2 75 + 74 Gaps:2 22.15 325 55.56 2e-16 mol:protein length:325 2-isopropylmalate synthase
blastp_pdb 3mi3_B 32 142 + 111 Gaps:3 25.53 423 32.41 7e-10 mol:protein length:423 Homocitrate synthase mitochondrial
blastp_pdb 3mi3_A 32 142 + 111 Gaps:3 25.53 423 32.41 7e-10 mol:protein length:423 Homocitrate synthase mitochondrial
blastp_pdb 3ivu_B 32 142 + 111 Gaps:3 25.53 423 32.41 7e-10 mol:protein length:423 Homocitrate synthase mitochondrial
blastp_pdb 3ivu_A 32 142 + 111 Gaps:3 25.53 423 32.41 7e-10 mol:protein length:423 Homocitrate synthase mitochondrial
blastp_pdb 3ivt_B 32 142 + 111 Gaps:3 25.53 423 32.41 7e-10 mol:protein length:423 Homocitrate synthase mitochondrial
blastp_pdb 3ivt_A 32 142 + 111 Gaps:3 25.53 423 32.41 7e-10 mol:protein length:423 Homocitrate synthase mitochondrial
blastp_uniprot_sprot sp|Q9LPR4|LEU11_ARATH 2 296 + 295 none 46.75 631 78.64 2e-166 2-isopropylmalate synthase 1 chloroplastic OS Arabidopsis thaliana GN IPMS1 PE 1 SV 2
blastp_uniprot_sprot sp|Q9C550|LEU12_ARATH 2 295 + 294 Gaps:2 46.91 631 79.05 7e-166 2-isopropylmalate synthase 2 chloroplastic OS Arabidopsis thaliana GN IPMS2 PE 1 SV 1
blastp_uniprot_sprot sp|O04974|LEU1B_SOLPN 2 282 + 281 none 45.92 612 73.67 1e-150 2-isopropylmalate synthase B OS Solanum pennellii GN IPMSB PE 2 SV 1
blastp_uniprot_sprot sp|O04973|LEU1A_SOLPN 2 282 + 281 none 47.71 589 71.89 8e-146 2-isopropylmalate synthase A OS Solanum pennellii GN IPMSA PE 2 SV 1
blastp_uniprot_sprot sp|Q39891|LEU1_SOYBN 2 282 + 281 none 49.73 565 64.41 6e-125 Probable 2-isopropylmalate synthase OS Glycine max GN GMN56 PE 2 SV 1
blastp_uniprot_sprot sp|P48576|LEU1_SYNY3 20 286 + 267 Gaps:21 47.65 533 52.36 1e-78 2-isopropylmalate synthase OS Synechocystis sp. (strain PCC 6803 / Kazusa) GN leuA PE 3 SV 1
blastp_uniprot_sprot sp|B7KJX8|LEU1_CYAP7 20 296 + 277 Gaps:18 48.69 536 51.72 1e-75 2-isopropylmalate synthase OS Cyanothece sp. (strain PCC 7424) GN leuA PE 3 SV 1
blastp_uniprot_sprot sp|B7JYP4|LEU1_CYAP8 20 279 + 260 Gaps:17 45.34 536 52.26 3e-75 2-isopropylmalate synthase OS Cyanothece sp. (strain PCC 8801) GN leuA PE 3 SV 1
blastp_uniprot_sprot sp|B1WQQ4|LEU1_CYAA5 20 283 + 264 Gaps:17 46.00 537 52.23 1e-74 2-isopropylmalate synthase OS Cyanothece sp. (strain ATCC 51142) GN leuA PE 3 SV 1
blastp_uniprot_sprot sp|Q7NI93|LEU1_GLOVI 22 277 + 256 Gaps:17 44.42 538 53.14 6e-74 2-isopropylmalate synthase OS Gloeobacter violaceus (strain PCC 7421) GN leuA PE 3 SV 1

7 Domain Motifs

Analysis Begin End Length Domain Identifier Cross Ref Description Inter Pro
Gene3D 2 111 110 G3DSA:3.20.20.70 none none IPR013785
PANTHER 2 278 277 PTHR10277:SF9 none none none
SMART 133 278 146 SM00917 "KEGG:00290+2.3.3.13","KEGG:00620+2.3.3.13","MetaCyc:PWY-6871","UniPathway:UPA00048" LeuA allosteric (dimerisation) domain IPR013709
SUPERFAMILY 155 277 123 SSF110921 "KEGG:00290+2.3.3.13","KEGG:00620+2.3.3.13","MetaCyc:PWY-6871","UniPathway:UPA00048" none IPR013709
PANTHER 2 278 277 PTHR10277 none none none
Coils 98 119 22 Coil none none none
Pfam 134 278 145 PF08502 "KEGG:00290+2.3.3.13","KEGG:00620+2.3.3.13","MetaCyc:PWY-6871","UniPathway:UPA00048" LeuA allosteric (dimerisation) domain IPR013709

0 Localization

1 Qtllist

Qtl Name Chromosome Name Linkage Group Prox Marker Dist Marker Position QTL Pos One Pos Two Test Type Test Value R 2
Champenoux_2015_nPriLBD_3P Qrob_Chr10 10 v_15000_157 v_15000_310 15,68 15,9 15,91 lod 2.4 5.5

0 Targeting