Protein : Qrob_P0577510.2 Q. robur
Protein Identifier  ? Qrob_P0577510.2 Organism . Name  Quercus robur
Score  90.2 Score Type  egn
Protein Description  (M=5) 2.3.3.13 - 2-isopropylmalate synthase. Code Enzyme  EC:2.3.3.13
Gene Prediction Quality  validated Protein length 

Sequence

Length: 377  
Kegg Orthology  K01649
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0 Synonyms

3 GO Terms

Identifier Name Description
GO:0003824 catalytic activity Catalysis of a biochemical reaction at physiological temperatures. In biologically catalyzed reactions, the reactants are known as substrates, and the catalysts are naturally occurring macromolecular substances known as enzymes. Enzymes possess specific binding sites for substrates, and are usually composed wholly or largely of protein, but RNA that has catalytic activity (ribozyme) is often also regarded as enzymatic.
GO:0046912 transferase activity, transferring acyl groups, acyl groups converted into alkyl on transfer Catalysis of the transfer of an acyl group from one compound (donor) to another (acceptor), with the acyl group being converted into alkyl on transfer.
GO:0019752 carboxylic acid metabolic process The chemical reactions and pathways involving carboxylic acids, any organic acid containing one or more carboxyl (COOH) groups or anions (COO-).

41 Blast

Analysis Hit Start End Strand Length Note Hit Coverage Hit Length Hit Pident E Val Hit Description
blastp_kegg lcl|pvu:PHAVU_007G004600g 22 363 + 342 Gaps:29 73.33 435 79.00 1e-170 hypothetical protein
blastp_kegg lcl|cit:102620455 14 363 + 350 Gaps:38 50.65 620 82.17 1e-168 2-isopropylmalate synthase 1 chloroplastic-like
blastp_kegg lcl|fve:101309776 26 363 + 338 Gaps:38 47.77 628 83.67 3e-168 2-isopropylmalate synthase 2 chloroplastic-like
blastp_kegg lcl|pmum:103331792 53 363 + 311 Gaps:33 45.18 633 86.01 3e-166 2-isopropylmalate synthase 1 chloroplastic-like
blastp_kegg lcl|mdm:103454775 1 363 + 363 Gaps:61 71.73 474 75.00 2e-165 2-isopropylmalate synthase 2 chloroplastic-like
blastp_kegg lcl|ath:AT1G74040 62 363 + 302 Gaps:26 43.74 631 85.87 4e-165 IMS1 2-isopropylmalate synthase 2
blastp_kegg lcl|cmo:103496846 52 363 + 312 Gaps:29 44.15 641 86.22 5e-165 2-isopropylmalate synthase 2 chloroplastic-like
blastp_kegg lcl|csv:101224798 38 363 + 326 Gaps:40 47.57 639 81.91 5e-164 2-isopropylmalate synthase 2 chloroplastic-like
blastp_kegg lcl|rcu:RCOM_1267040 32 363 + 332 Gaps:29 48.89 632 79.61 5e-164 isopropylmalate synthase putative (EC:2.3.3.13)
blastp_kegg lcl|mdm:103405612 1 363 + 363 Gaps:42 71.43 469 74.93 5e-164 2-isopropylmalate synthase 1 chloroplastic-like
blastp_pdb 3rmj_B 80 363 + 284 Gaps:35 67.30 370 59.04 2e-83 mol:protein length:370 2-isopropylmalate synthase
blastp_pdb 3rmj_A 80 363 + 284 Gaps:35 67.30 370 59.04 2e-83 mol:protein length:370 2-isopropylmalate synthase
blastp_pdb 3ewb_X 89 365 + 277 Gaps:35 82.59 293 53.72 5e-78 mol:protein length:293 2-isopropylmalate synthase
blastp_pdb 3eeg_B 91 363 + 273 Gaps:35 73.23 325 52.52 9e-72 mol:protein length:325 2-isopropylmalate synthase
blastp_pdb 3eeg_A 91 363 + 273 Gaps:35 73.23 325 52.52 9e-72 mol:protein length:325 2-isopropylmalate synthase
blastp_pdb 3mi3_B 62 356 + 295 Gaps:47 60.52 423 34.38 2e-19 mol:protein length:423 Homocitrate synthase mitochondrial
blastp_pdb 3mi3_A 62 356 + 295 Gaps:47 60.52 423 34.38 2e-19 mol:protein length:423 Homocitrate synthase mitochondrial
blastp_pdb 3ivu_B 62 356 + 295 Gaps:47 60.52 423 34.38 2e-19 mol:protein length:423 Homocitrate synthase mitochondrial
blastp_pdb 3ivu_A 62 356 + 295 Gaps:47 60.52 423 34.38 2e-19 mol:protein length:423 Homocitrate synthase mitochondrial
blastp_pdb 3ivt_B 62 356 + 295 Gaps:47 60.52 423 34.38 2e-19 mol:protein length:423 Homocitrate synthase mitochondrial
blastp_uniprot_sprot sp|Q9C550|LEU12_ARATH 62 363 + 302 Gaps:26 43.74 631 85.87 1e-166 2-isopropylmalate synthase 2 chloroplastic OS Arabidopsis thaliana GN IPMS2 PE 1 SV 1
blastp_uniprot_sprot sp|Q9LPR4|LEU11_ARATH 35 363 + 329 Gaps:28 47.70 631 79.40 3e-161 2-isopropylmalate synthase 1 chloroplastic OS Arabidopsis thaliana GN IPMS1 PE 1 SV 2
blastp_uniprot_sprot sp|O04973|LEU1A_SOLPN 74 363 + 290 Gaps:26 44.82 589 82.20 3e-156 2-isopropylmalate synthase A OS Solanum pennellii GN IPMSA PE 2 SV 1
blastp_uniprot_sprot sp|O04974|LEU1B_SOLPN 1 363 + 363 Gaps:50 52.12 612 72.10 1e-149 2-isopropylmalate synthase B OS Solanum pennellii GN IPMSB PE 2 SV 1
blastp_uniprot_sprot sp|Q39891|LEU1_SOYBN 57 363 + 307 Gaps:27 49.56 565 75.00 4e-139 Probable 2-isopropylmalate synthase OS Glycine max GN GMN56 PE 2 SV 1
blastp_uniprot_sprot sp|Q9FG67|MAM1_ARATH 19 363 + 345 Gaps:41 60.47 506 59.15 1e-118 Methylthioalkylmalate synthase 1 chloroplastic OS Arabidopsis thaliana GN MAM1 PE 1 SV 1
blastp_uniprot_sprot sp|Q9FN52|MAM3_ARATH 54 363 + 310 Gaps:27 56.66 503 60.00 1e-116 Methylthioalkylmalate synthase 3 chloroplastic OS Arabidopsis thaliana GN MAM3 PE 1 SV 1
blastp_uniprot_sprot sp|Q8VX04|MAM2_ARATH 19 363 + 345 Gaps:41 60.47 506 58.50 4e-116 Methylthioalkylmalate synthase 2 chloroplastic OS Arabidopsis thaliana GN MAM2 PE 2 SV 1
blastp_uniprot_sprot sp|Q8DJ32|LEU1_THEEB 75 363 + 289 Gaps:35 47.48 535 66.93 1e-98 2-isopropylmalate synthase OS Thermosynechococcus elongatus (strain BP-1) GN leuA PE 3 SV 1
blastp_uniprot_sprot sp|B7JYP4|LEU1_CYAP8 84 363 + 280 Gaps:32 46.27 536 66.53 1e-97 2-isopropylmalate synthase OS Cyanothece sp. (strain PCC 8801) GN leuA PE 3 SV 1

15 Domain Motifs

Analysis Begin End Length Domain Identifier Cross Ref Description Inter Pro
ProSitePatterns 96 112 17 PS00815 "KEGG:00290+2.3.3.13","KEGG:00620+2.3.3.13","MetaCyc:PWY-6871","UniPathway:UPA00048" Alpha-isopropylmalate and homocitrate synthases signature 1. IPR002034
PANTHER 336 363 28 PTHR10277:SF9 none none none
PANTHER 49 309 261 PTHR10277:SF9 none none none
Phobius 323 376 54 CYTOPLASMIC_DOMAIN none Region of a membrane-bound protein predicted to be outside the membrane, in the cytoplasm. none
Phobius 1 299 299 NON_CYTOPLASMIC_DOMAIN none Region of a membrane-bound protein predicted to be outside the membrane, in the extracellular region. none
Gene3D 333 363 31 G3DSA:3.20.20.70 none none IPR013785
Gene3D 85 308 224 G3DSA:3.20.20.70 none none IPR013785
Phobius 300 322 23 TRANSMEMBRANE none Region of a membrane-bound protein predicted to be embedded in the membrane. none
SUPERFAMILY 333 363 31 SSF51569 none none none
SUPERFAMILY 85 308 224 SSF51569 none none none
PANTHER 336 363 28 PTHR10277 none none none
PANTHER 49 309 261 PTHR10277 none none none
Pfam 335 363 29 PF00682 none HMGL-like IPR000891
Pfam 97 308 212 PF00682 none HMGL-like IPR000891
ProSiteProfiles 89 376 288 PS50991 none Pyruvate carboxyltransferase domain. IPR000891

1 Localization

Analysis Start End Length
SignalP_GRAM_POSITIVE 1 19 18

1 Qtllist

Qtl Name Chromosome Name Linkage Group Prox Marker Dist Marker Position QTL Pos One Pos Two Test Type Test Value R 2
Champenoux_2015_nPriLBD_3P Qrob_Chr10 10 v_15000_157 v_15000_310 15,68 15,9 15,91 lod 2.4 5.5

0 Targeting